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PubMed code 12904063

Compile data set for download or QSAR
Found 69 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28701
PNG
(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)
Show SMILES CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)
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n/an/an/an/a>7.80E+4n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131737
PNG
(2-{4-Methoxy-3-[3-(4-trifluoromethyl-phenyl)-propy...)
Show SMILES CCC(Cc1ccc(OC)c(CCCc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C22H25F3O3/c1-3-17(21(26)27)13-16-9-12-20(28-2)18(14-16)6-4-5-15-7-10-19(11-8-15)22(23,24)25/h7-12,14,17H,3-6,13H2,1-2H3,(H,26,27)
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n/an/an/an/a 640n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50107546
PNG
(2-(3-((4-(trifluoromethyl)benzyl)carbamoyl)-4-meth...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-15(20(27)28)10-14-6-9-18(29-2)17(11-14)19(26)25-12-13-4-7-16(8-5-13)21(22,23)24/h4-9,11,15H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 3.60E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131750
PNG
(2-[4-Methoxy-3-(4-phenethyloxy-benzylcarbamoyl)-be...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(OCCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C28H31NO5/c1-3-23(28(31)32)17-22-11-14-26(33-2)25(18-22)27(30)29-19-21-9-12-24(13-10-21)34-16-15-20-7-5-4-6-8-20/h4-14,18,23H,3,15-17,19H2,1-2H3,(H,29,30)(H,31,32)
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n/an/an/an/a 2.70E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM28701
PNG
(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)
Show SMILES CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)
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n/an/an/an/a>1.37E+5n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131744
PNG
(2-Ethylsulfanyl-3-[4-methoxy-3-(4-trifluoromethyl-...)
Show SMILES CCSC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4S/c1-3-30-18(20(27)28)11-14-6-9-17(29-2)16(10-14)19(26)25-12-13-4-7-15(8-5-13)21(22,23)24/h4-10,18H,3,11-12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 2.80E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50107541
PNG
(2-Ethoxy-3-[4-methoxy-3-(4-trifluoromethyl-benzylc...)
Show SMILES CCOC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO5/c1-3-30-18(20(27)28)11-14-6-9-17(29-2)16(10-14)19(26)25-12-13-4-7-15(8-5-13)21(22,23)24/h4-10,18H,3,11-12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 3.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50107545
PNG
(3-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES COc1ccc(CC(C)C(O)=O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H20F3NO4/c1-12(19(26)27)9-14-5-8-17(28-2)16(10-14)18(25)24-11-13-3-6-15(7-4-13)20(21,22)23/h3-8,10,12H,9,11H2,1-2H3,(H,24,25)(H,26,27)
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n/an/an/an/a 2.80E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107542
PNG
(3-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES COc1ccc(CCC(O)=O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C19H18F3NO4/c1-27-16-8-4-12(5-9-17(24)25)10-15(16)18(26)23-11-13-2-6-14(7-3-13)19(20,21)22/h2-4,6-8,10H,5,9,11H2,1H3,(H,23,26)(H,24,25)
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n/an/an/an/a 1.30E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131740
PNG
(2-[4-Methoxy-3-(3-methoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1cccc(OC)c1)C(O)=O
Show InChI InChI=1S/C21H25NO5/c1-4-16(21(24)25)10-14-8-9-19(27-3)18(12-14)20(23)22-13-15-6-5-7-17(11-15)26-2/h5-9,11-12,16H,4,10,13H2,1-3H3,(H,22,23)(H,24,25)
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n/an/an/an/a 3.10E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131745
PNG
(2-{4-Methoxy-3-[3-(4-trifluoromethyl-phenyl)-propi...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)CCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C22H23F3O4/c1-3-16(21(27)28)12-15-7-11-20(29-2)18(13-15)19(26)10-6-14-4-8-17(9-5-14)22(23,24)25/h4-5,7-9,11,13,16H,3,6,10,12H2,1-2H3,(H,27,28)
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n/an/an/an/a 320n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131749
PNG
(2-[4-Methoxy-3-(4-phenoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(Oc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C26H27NO5/c1-3-20(26(29)30)15-19-11-14-24(31-2)23(16-19)25(28)27-17-18-9-12-22(13-10-18)32-21-7-5-4-6-8-21/h4-14,16,20H,3,15,17H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 2.40E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107543
PNG
(4-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES COc1ccc(CCCC(O)=O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H20F3NO4/c1-28-17-10-7-13(3-2-4-18(25)26)11-16(17)19(27)24-12-14-5-8-15(9-6-14)20(21,22)23/h5-11H,2-4,12H2,1H3,(H,24,27)(H,25,26)
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n/an/an/an/a 2.20E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131742
PNG
(2-{4-Methoxy-3-[2-(4-trifluoromethyl-phenyl)-ethyl...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C22H24F3NO4/c1-3-16(21(28)29)12-15-6-9-19(30-2)18(13-15)20(27)26-11-10-14-4-7-17(8-5-14)22(23,24)25/h4-9,13,16H,3,10-12H2,1-2H3,(H,26,27)(H,28,29)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131754
PNG
(2-[4-Methoxy-3-(4-trifluoromethyl-phenylcarbamoyl)...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)Nc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C20H20F3NO4/c1-3-13(19(26)27)10-12-4-9-17(28-2)16(11-12)18(25)24-15-7-5-14(6-8-15)20(21,22)23/h4-9,11,13H,3,10H2,1-2H3,(H,24,25)(H,26,27)
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n/an/an/an/a 6.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131743
PNG
(2-{4-Methoxy-3-[2-(4-trifluoromethyl-phenyl)-ethox...)
Show SMILES CCC(Cc1ccc(OC)c(OCCc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H23F3O4/c1-3-16(20(25)26)12-15-6-9-18(27-2)19(13-15)28-11-10-14-4-7-17(8-5-14)21(22,23)24/h4-9,13,16H,3,10-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 400n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50075315
PNG
(5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...)
Show SMILES COc1ccc(Cc2sc(=O)[nH]c2O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H17F3N2O4S/c1-29-15-7-4-12(9-16-18(27)25-19(28)30-16)8-14(15)17(26)24-10-11-2-5-13(6-3-11)20(21,22)23/h2-8,27H,9-10H2,1H3,(H,24,26)(H,25,28)
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n/an/an/an/a 1.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131743
PNG
(2-{4-Methoxy-3-[2-(4-trifluoromethyl-phenyl)-ethox...)
Show SMILES CCC(Cc1ccc(OC)c(OCCc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H23F3O4/c1-3-16(20(25)26)12-15-6-9-18(27-2)19(13-15)28-11-10-14-4-7-17(8-5-14)21(22,23)24/h4-9,13,16H,3,10-12H2,1-2H3,(H,25,26)
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n/an/an/an/a 680n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131742
PNG
(2-{4-Methoxy-3-[2-(4-trifluoromethyl-phenyl)-ethyl...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C22H24F3NO4/c1-3-16(21(28)29)12-15-6-9-19(30-2)18(13-15)20(27)26-11-10-14-4-7-17(8-5-14)22(23,24)25/h4-9,13,16H,3,10-12H2,1-2H3,(H,26,27)(H,28,29)
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n/an/an/an/a 740n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107541
PNG
(2-Ethoxy-3-[4-methoxy-3-(4-trifluoromethyl-benzylc...)
Show SMILES CCOC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO5/c1-3-30-18(20(27)28)11-14-6-9-17(29-2)16(10-14)19(26)25-12-13-4-7-15(8-5-13)21(22,23)24/h4-10,18H,3,11-12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131747
PNG
(2-[4-Methoxy-3-(3-phenoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C26H27NO5/c1-3-20(26(29)30)14-18-12-13-24(31-2)23(16-18)25(28)27-17-19-8-7-11-22(15-19)32-21-9-5-4-6-10-21/h4-13,15-16,20H,3,14,17H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 6.20E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131753
PNG
(2-[4-Methoxy-3-(4-phenethyl-benzylcarbamoyl)-benzy...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(CCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C28H31NO4/c1-3-24(28(31)32)17-23-15-16-26(33-2)25(18-23)27(30)29-19-22-13-11-21(12-14-22)10-9-20-7-5-4-6-8-20/h4-8,11-16,18,24H,3,9-10,17,19H2,1-2H3,(H,29,30)(H,31,32)
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n/an/an/an/a 5.60E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131753
PNG
(2-[4-Methoxy-3-(4-phenethyl-benzylcarbamoyl)-benzy...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(CCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C28H31NO4/c1-3-24(28(31)32)17-23-15-16-26(33-2)25(18-23)27(30)29-19-22-13-11-21(12-14-22)10-9-20-7-5-4-6-8-20/h4-8,11-16,18,24H,3,9-10,17,19H2,1-2H3,(H,29,30)(H,31,32)
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n/an/an/an/a 5.40E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131738
PNG
(2-[4-Methoxy-3-(4-trifluoromethoxy-benzylcarbamoyl...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(OC(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C21H22F3NO5/c1-3-15(20(27)28)10-14-6-9-18(29-2)17(11-14)19(26)25-12-13-4-7-16(8-5-13)30-21(22,23)24/h4-9,11,15H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 900n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107551
PNG
(2-Methoxy-3-[4-methoxy-3-(4-trifluoromethyl-benzyl...)
Show SMILES COC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C20H20F3NO5/c1-28-16-8-5-13(10-17(29-2)19(26)27)9-15(16)18(25)24-11-12-3-6-14(7-4-12)20(21,22)23/h3-9,17H,10-11H2,1-2H3,(H,24,25)(H,26,27)
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n/an/an/an/a 230n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131747
PNG
(2-[4-Methoxy-3-(3-phenoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1cccc(Oc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C26H27NO5/c1-3-20(26(29)30)14-18-12-13-24(31-2)23(16-18)25(28)27-17-19-8-7-11-22(15-19)32-21-9-5-4-6-10-21/h4-13,15-16,20H,3,14,17H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 400n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50107549
PNG
(2-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES CCCCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C23H26F3NO4/c1-3-4-5-17(22(29)30)12-16-8-11-20(31-2)19(13-16)21(28)27-14-15-6-9-18(10-7-15)23(24,25)26/h6-11,13,17H,3-5,12,14H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 2.50E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50085042
PNG
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
Show SMILES CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
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n/an/an/an/a 4.10E+4n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107547
PNG
(2-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES COc1ccc(CC(C(C)C)C(O)=O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H24F3NO4/c1-13(2)17(21(28)29)10-15-6-9-19(30-3)18(11-15)20(27)26-12-14-4-7-16(8-5-14)22(23,24)25/h4-9,11,13,17H,10,12H2,1-3H3,(H,26,27)(H,28,29)
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n/an/an/an/a 290n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107545
PNG
(3-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES COc1ccc(CC(C)C(O)=O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H20F3NO4/c1-12(19(26)27)9-14-5-8-17(28-2)16(10-14)18(25)24-11-13-3-6-15(7-4-13)20(21,22)23/h3-8,10,12H,9,11H2,1-2H3,(H,24,25)(H,26,27)
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n/an/an/an/a 240n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50075315
PNG
(5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(...)
Show SMILES COc1ccc(Cc2sc(=O)[nH]c2O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H17F3N2O4S/c1-29-15-7-4-12(9-16-18(27)25-19(28)30-16)8-14(15)17(26)24-10-11-2-5-13(6-3-11)20(21,22)23/h2-8,27H,9-10H2,1H3,(H,24,26)(H,25,28)
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n/an/an/an/a 800n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107546
PNG
(2-(3-((4-(trifluoromethyl)benzyl)carbamoyl)-4-meth...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-15(20(27)28)10-14-6-9-18(29-2)17(11-14)19(26)25-12-13-4-7-16(8-5-13)21(22,23)24/h4-9,11,15H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 40n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131751
PNG
(2-[4-Methoxy-3-(4-methoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(OC)cc1)C(O)=O
Show InChI InChI=1S/C21H25NO5/c1-4-16(21(24)25)11-15-7-10-19(27-3)18(12-15)20(23)22-13-14-5-8-17(26-2)9-6-14/h5-10,12,16H,4,11,13H2,1-3H3,(H,22,23)(H,24,25)
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n/an/an/an/a 1.20E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131752
PNG
(2-{4-Methoxy-3-[(4-trifluoromethyl-phenylcarbamoyl...)
Show SMILES CCC(Cc1ccc(OC)c(CC(=O)Nc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-14(20(27)28)10-13-4-9-18(29-2)15(11-13)12-19(26)25-17-7-5-16(6-8-17)21(22,23)24/h4-9,11,14H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 20n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131751
PNG
(2-[4-Methoxy-3-(4-methoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(OC)cc1)C(O)=O
Show InChI InChI=1S/C21H25NO5/c1-4-16(21(24)25)11-15-7-10-19(27-3)18(12-15)20(23)22-13-14-5-8-17(26-2)9-6-14/h5-10,12,16H,4,11,13H2,1-3H3,(H,22,23)(H,24,25)
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n/an/an/an/a 6.60E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131738
PNG
(2-[4-Methoxy-3-(4-trifluoromethoxy-benzylcarbamoyl...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(OC(F)(F)F)cc1)C(O)=O
Show InChI InChI=1S/C21H22F3NO5/c1-3-15(20(27)28)10-14-6-9-18(29-2)17(11-14)19(26)25-12-13-4-7-16(8-5-13)30-21(22,23)24/h4-9,11,15H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 43n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131741
PNG
(2-[4-Methoxy-3-(3-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1cccc(c1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-15(20(27)28)9-13-7-8-18(29-2)17(11-13)19(26)25-12-14-5-4-6-16(10-14)21(22,23)24/h4-8,10-11,15H,3,9,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 1.80E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131739
PNG
((+/-)-2-(4-methoxy-3-((4-(trifluoromethyl)benzamid...)
Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-14(20(27)28)10-13-4-9-18(29-2)16(11-13)12-25-19(26)15-5-7-17(8-6-15)21(22,23)24/h4-9,11,14H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 40n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131736
PNG
(2-{3-[(Biphenyl-4-ylmethyl)-carbamoyl]-4-methoxy-b...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C26H27NO4/c1-3-20(26(29)30)15-19-11-14-24(31-2)23(16-19)25(28)27-17-18-9-12-22(13-10-18)21-7-5-4-6-8-21/h4-14,16,20H,3,15,17H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 110n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131735
PNG
(2-{4-Methoxy-3-[(4-trifluoromethyl-benzylamino)-me...)
Show SMILES CCC(Cc1ccc(OC)c(CNCc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H24F3NO3/c1-3-16(20(26)27)10-15-6-9-19(28-2)17(11-15)13-25-12-14-4-7-18(8-5-14)21(22,23)24/h4-9,11,16,25H,3,10,12-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 8.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50107546
PNG
(2-(3-((4-(trifluoromethyl)benzyl)carbamoyl)-4-meth...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-15(20(27)28)10-14-6-9-18(29-2)17(11-14)19(26)25-12-13-4-7-16(8-5-13)21(22,23)24/h4-9,11,15H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 400n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131748
PNG
(2-(3-Benzylcarbamoyl-4-methoxy-benzyl)-butyric aci...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccccc1)C(O)=O
Show InChI InChI=1S/C20H23NO4/c1-3-16(20(23)24)11-15-9-10-18(25-2)17(12-15)19(22)21-13-14-7-5-4-6-8-14/h4-10,12,16H,3,11,13H2,1-2H3,(H,21,22)(H,23,24)
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n/an/an/an/a 2.30E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131737
PNG
(2-{4-Methoxy-3-[3-(4-trifluoromethyl-phenyl)-propy...)
Show SMILES CCC(Cc1ccc(OC)c(CCCc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C22H25F3O3/c1-3-17(21(26)27)13-16-9-12-20(28-2)18(14-16)6-4-5-15-7-10-19(11-8-15)22(23,24)25/h7-12,14,17H,3-6,13H2,1-2H3,(H,26,27)
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n/an/an/an/a 860n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131744
PNG
(2-Ethylsulfanyl-3-[4-methoxy-3-(4-trifluoromethyl-...)
Show SMILES CCSC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4S/c1-3-30-18(20(27)28)11-14-6-9-17(29-2)16(10-14)19(26)25-12-13-4-7-15(8-5-13)21(22,23)24/h4-10,18H,3,11-12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 3.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM28701
PNG
(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)
Show SMILES CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(O)=O
Show InChI InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)
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n/an/an/an/a>1.43E+5n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107544
PNG
(3-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES COc1ccc(CC(C)(C)C(O)=O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C21H22F3NO4/c1-20(2,19(27)28)11-14-6-9-17(29-3)16(10-14)18(26)25-12-13-4-7-15(8-5-13)21(22,23)24/h4-10H,11-12H2,1-3H3,(H,25,26)(H,27,28)
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n/an/an/an/a 2.90E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131735
PNG
(2-{4-Methoxy-3-[(4-trifluoromethyl-benzylamino)-me...)
Show SMILES CCC(Cc1ccc(OC)c(CNCc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H24F3NO3/c1-3-16(20(26)27)10-15-6-9-19(28-2)17(11-15)13-25-12-14-4-7-18(8-5-14)21(22,23)24/h4-9,11,16,25H,3,10,12-13H2,1-2H3,(H,26,27)
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n/an/an/an/a 4.90E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131736
PNG
(2-{3-[(Biphenyl-4-ylmethyl)-carbamoyl]-4-methoxy-b...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C26H27NO4/c1-3-20(26(29)30)15-19-11-14-24(31-2)23(16-19)25(28)27-17-18-9-12-22(13-10-18)21-7-5-4-6-8-21/h4-14,16,20H,3,15,17H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 4.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131748
PNG
(2-(3-Benzylcarbamoyl-4-methoxy-benzyl)-butyric aci...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccccc1)C(O)=O
Show InChI InChI=1S/C20H23NO4/c1-3-16(20(23)24)11-15-9-10-18(25-2)17(12-15)19(22)21-13-14-7-5-4-6-8-14/h4-10,12,16H,3,11,13H2,1-2H3,(H,21,22)(H,23,24)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107550
PNG
(2-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES CCCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C22H24F3NO4/c1-3-4-16(21(28)29)11-15-7-10-19(30-2)18(12-15)20(27)26-13-14-5-8-17(9-6-14)22(23,24)25/h5-10,12,16H,3-4,11,13H2,1-2H3,(H,26,27)(H,28,29)
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n/an/an/an/a 360n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50107543
PNG
(4-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES COc1ccc(CCCC(O)=O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C20H20F3NO4/c1-28-17-10-7-13(3-2-4-18(25)26)11-16(17)19(27)24-12-14-5-8-15(9-6-14)20(21,22)23/h5-11H,2-4,12H2,1H3,(H,24,27)(H,25,26)
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n/an/an/an/a 3.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131745
PNG
(2-{4-Methoxy-3-[3-(4-trifluoromethyl-phenyl)-propi...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)CCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C22H23F3O4/c1-3-16(21(27)28)12-15-7-11-20(29-2)18(13-15)19(26)10-6-14-4-8-17(9-5-14)22(23,24)25/h4-5,7-9,11,13,16H,3,6,10,12H2,1-2H3,(H,27,28)
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n/an/an/an/a 7.40E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131739
PNG
((+/-)-2-(4-methoxy-3-((4-(trifluoromethyl)benzamid...)
Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-14(20(27)28)10-13-4-9-18(29-2)16(11-13)12-25-19(26)15-5-7-17(8-6-15)21(22,23)24/h4-9,11,14H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131746
PNG
(2-[4-Methoxy-3-(2-methoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccccc1OC)C(O)=O
Show InChI InChI=1S/C21H25NO5/c1-4-15(21(24)25)11-14-9-10-19(27-3)17(12-14)20(23)22-13-16-7-5-6-8-18(16)26-2/h5-10,12,15H,4,11,13H2,1-3H3,(H,22,23)(H,24,25)
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n/an/an/an/a 9.40E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107548
PNG
(2-Ethyl-2-[4-methoxy-3-(4-trifluoromethyl-benzylca...)
Show SMILES CCC(CC)(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C23H26F3NO4/c1-4-22(5-2,21(29)30)13-16-8-11-19(31-3)18(12-16)20(28)27-14-15-6-9-17(10-7-15)23(24,25)26/h6-12H,4-5,13-14H2,1-3H3,(H,27,28)(H,29,30)
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n/an/an/an/a 2.80E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50107549
PNG
(2-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES CCCCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C23H26F3NO4/c1-3-4-5-17(22(29)30)12-16-8-11-20(31-2)19(13-16)21(28)27-14-15-6-9-18(10-7-15)23(24,25)26/h6-11,13,17H,3-5,12,14H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 1.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131749
PNG
(2-[4-Methoxy-3-(4-phenoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(Oc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C26H27NO5/c1-3-20(26(29)30)15-19-11-14-24(31-2)23(16-19)25(28)27-17-18-9-12-22(13-10-18)32-21-7-5-4-6-8-21/h4-14,16,20H,3,15,17H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 3.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50131739
PNG
((+/-)-2-(4-methoxy-3-((4-(trifluoromethyl)benzamid...)
Show SMILES CCC(Cc1ccc(OC)c(CNC(=O)c2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-14(20(27)28)10-13-4-9-18(29-2)16(11-13)12-25-19(26)15-5-7-17(8-6-15)21(22,23)24/h4-9,11,14H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 120n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Rattus norvegicus)
BDBM50085042
PNG
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
Show SMILES CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
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n/an/an/an/a 4.90E+4n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on rat Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected C...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta


(Homo sapiens (Human))
BDBM50107550
PNG
(2-[4-Methoxy-3-(4-trifluoromethyl-benzylcarbamoyl)...)
Show SMILES CCCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C22H24F3NO4/c1-3-4-16(21(28)29)11-15-7-10-19(30-2)18(12-15)20(27)26-13-14-5-8-17(9-6-14)22(23,24)25/h5-10,12,16H,3-4,11,13H2,1-2H3,(H,26,27)(H,28,29)
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n/an/an/an/a 2.40E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50131750
PNG
(2-[4-Methoxy-3-(4-phenethyloxy-benzylcarbamoyl)-be...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(OCCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C28H31NO5/c1-3-23(28(31)32)17-22-11-14-26(33-2)25(18-22)27(30)29-19-21-9-12-24(13-10-21)34-16-15-20-7-5-4-6-8-20/h4-14,18,23H,3,15-17,19H2,1-2H3,(H,29,30)(H,31,32)
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n/an/an/an/a 3.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131749
PNG
(2-[4-Methoxy-3-(4-phenoxy-benzylcarbamoyl)-benzyl]...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(Oc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C26H27NO5/c1-3-20(26(29)30)15-19-11-14-24(31-2)23(16-19)25(28)27-17-18-9-12-22(13-10-18)32-21-7-5-4-6-8-21/h4-14,16,20H,3,15,17H2,1-2H3,(H,27,28)(H,29,30)
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n/an/an/an/a 90n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131744
PNG
(2-Ethylsulfanyl-3-[4-methoxy-3-(4-trifluoromethyl-...)
Show SMILES CCSC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4S/c1-3-30-18(20(27)28)11-14-6-9-17(29-2)16(10-14)19(26)25-12-13-4-7-15(8-5-13)21(22,23)24/h4-10,18H,3,11-12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50107541
PNG
(2-Ethoxy-3-[4-methoxy-3-(4-trifluoromethyl-benzylc...)
Show SMILES CCOC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO5/c1-3-30-18(20(27)28)11-14-6-9-17(29-2)16(10-14)19(26)25-12-13-4-7-15(8-5-13)21(22,23)24/h4-10,18H,3,11-12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 2.80E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cells


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131755
PNG
(2-[3-(4-Benzyloxy-benzylcarbamoyl)-4-methoxy-benzy...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(OCc2ccccc2)cc1)C(O)=O
Show InChI InChI=1S/C27H29NO5/c1-3-22(27(30)31)15-21-11-14-25(32-2)24(16-21)26(29)28-17-19-9-12-23(13-10-19)33-18-20-7-5-4-6-8-20/h4-14,16,22H,3,15,17-18H2,1-2H3,(H,28,29)(H,30,31)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131757
PNG
(2-{4-Methoxy-3-[2-(4-trifluoromethyl-phenyl)-acety...)
Show SMILES CCC(Cc1ccc(OC)c(NC(=O)Cc2ccc(cc2)C(F)(F)F)c1)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-15(20(27)28)10-14-6-9-18(29-2)17(11-14)25-19(26)12-13-4-7-16(8-5-13)21(22,23)24/h4-9,11,15H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)
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n/an/an/an/a 130n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50085042
PNG
(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic a...)
Show SMILES CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
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n/an/an/an/a 5.00E+4n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on dog Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected C...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50131756
PNG
(2-[3-(4-Chloro-benzylcarbamoyl)-4-methoxy-benzyl]-...)
Show SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C20H22ClNO4/c1-3-15(20(24)25)10-14-6-9-18(26-2)17(11-14)19(23)22-12-13-4-7-16(21)8-5-13/h4-9,11,15H,3,10,12H2,1-2H3,(H,22,23)(H,24,25)
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n/an/an/an/a 3.00E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha


(Rattus norvegicus)
BDBM50109110
PNG
((S)-2-(4-methoxy-3-(4-(trifluoromethyl)benzylcarba...)
Show SMILES CC[C@@H](Cc1ccc(OC)c(c1)C(=O)NCc1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C21H22F3NO4/c1-3-15(20(27)28)10-14-6-9-18(29-2)17(11-14)19(26)25-12-13-4-7-16(8-5-13)21(22,23)24/h4-9,11,15H,3,10,12H2,1-2H3,(H,25,26)(H,27,28)/t15-/m0/s1
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n/an/an/an/a 5.20E+3n/an/an/an/a



Kyorin Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
In vitro effective concentration for agonist activity on rat Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected C...


J Med Chem 46: 3581-99 (2003)


Article DOI: 10.1021/jm0205144
BindingDB Entry DOI: 10.7270/Q2R78DMX
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%