Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50013584
LigandPNGBDBM50132175(2-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  440nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132169((3-Chloro-phenyl)-(3-isopropyl-1H-pyrazolo[4,3-d]p...)
Affinity DataIC50:  900nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132178(5-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132183((3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)-pen...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132185(Benzyl-(3-isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132172(3-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132179(4-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132174((3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)-(4-...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132167(CHEMBL103206 | Furan-2-ylmethyl-(3-isopropyl-1H-py...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132177(3-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-phenol...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM10641(6-(benzylamino)-9-isopropylpurine | CHEMBL85015 | ...)
Affinity DataIC50:  3.60E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132176((9-Isopropyl-9H-purin-6-yl)-(4-methoxy-benzyl)-ami...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132171(4-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-phenol...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132170(2-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-phenol...)
Affinity DataIC50:  4.40E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132186(5-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-2-meth...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132180((3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)-(3-...)
Affinity DataIC50:  4.50E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132173((3-Chloro-phenyl)-(9-isopropyl-9H-purin-6-yl)-amin...)
Affinity DataIC50:  5.90E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132182((9-Isopropyl-9H-purin-6-yl)-pentyl-amine | CHEMBL9...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132168(CHEMBL103798 | Furan-2-ylmethyl-(9-isopropyl-9H-pu...)
Affinity DataIC50:  9.10E+3nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132187((2-Bromo-benzyl)-(3-isopropyl-1H-pyrazolo[4,3-d]py...)
Affinity DataIC50:  1.10E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132184((9-Isopropyl-9H-purin-6-yl)-(3-methyl-but-2-enyl)-...)
Affinity DataIC50:  1.70E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132169((3-Chloro-phenyl)-(3-isopropyl-1H-pyrazolo[4,3-d]p...)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132181((2-Bromo-benzyl)-(9-isopropyl-9H-purin-6-yl)-amine...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132178(5-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132187((2-Bromo-benzyl)-(3-isopropyl-1H-pyrazolo[4,3-d]py...)
Affinity DataIC50:  2.90E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132174((3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)-(4-...)
Affinity DataIC50:  4.60E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132181((2-Bromo-benzyl)-(9-isopropyl-9H-purin-6-yl)-amine...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132175(2-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132173((3-Chloro-phenyl)-(9-isopropyl-9H-purin-6-yl)-amin...)
Affinity DataIC50:  5.40E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132183((3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)-pen...)
Affinity DataIC50:  6.10E+4nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132185(Benzyl-(3-isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-...)
Affinity DataIC50:  6.60E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132172(3-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132186(5-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-2-meth...)
Affinity DataIC50:  1.04E+5nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132179(4-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  1.12E+5nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM10641(6-(benzylamino)-9-isopropylpurine | CHEMBL85015 | ...)
Affinity DataIC50:  1.13E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132170(2-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-phenol...)
Affinity DataIC50:  1.25E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132182((9-Isopropyl-9H-purin-6-yl)-pentyl-amine | CHEMBL9...)
Affinity DataIC50:  1.44E+5nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132180((3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)-(3-...)
Affinity DataIC50:  1.52E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50:  1.63E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132171(4-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-phenol...)
Affinity DataIC50: >1.67E+5nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132167(CHEMBL103206 | Furan-2-ylmethyl-(3-isopropyl-1H-py...)
Affinity DataIC50: >1.67E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132177(3-[(9-Isopropyl-9H-purin-6-ylamino)-methyl]-phenol...)
Affinity DataIC50: >1.67E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132168(CHEMBL103798 | Furan-2-ylmethyl-(9-isopropyl-9H-pu...)
Affinity DataIC50: >1.67E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132176((9-Isopropyl-9H-purin-6-yl)-(4-methoxy-benzyl)-ami...)
Affinity DataIC50: >1.67E+5nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132184((9-Isopropyl-9H-purin-6-yl)-(3-methyl-but-2-enyl)-...)
Affinity DataIC50: >1.67E+5nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed