Affinity Data by PubMed id=1310116

PubMed code 1310116

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
DNA topoisomerase II (Homo sapiens (Human))	BDBM50229974 (CHEMBL178077) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM21690 (1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM50229967 (CHEMBL263944) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM50229970 (CHEMBL367876) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM50229969 (CHEMBL554645) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM50229972 (CHEMBL174721) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM50229966 (DESMETHYL-OFLOXACIN \| Desmethyl-Ofloxacin (5%)) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
DNA topoisomerase II (Homo sapiens (Human))	BDBM50229965 (CHEMBL174892) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.930	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Ltd. Curated by ChEMBL					Assay Description The inhibitory activity was measured for the supercoiling activity of DNA gyrase isolated from Escherichia coli K-12 C600.				J Med Chem 35: 94-9 (1992) Article DOI: 10.1021/jm00079a011 BindingDB Entry DOI: 10.7270/Q2D79DNN
Kanebo Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%