Affinity Data by PubMed id=1310117

PubMed code 1310117

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate-NMDA (RAT)	BDBM18133 (2-aminoacetic acid \| CHEMBL773 \| Glycine \| [14C]Gl...) Show SMILES NCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000101 (2,5-Dihydro-1H-pyrrole-3-carboxylic acid \| CHEMBL3...) Show SMILES OC(=O)C1=CCNC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000102 (3-aminopropanoic acidbeta-alanine \| Alanine-beta \|...) Show SMILES NCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord ...				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000105 (CHEMBL72275 \| Hpro \| Prolin \| prolina \| proline \| ...) Show SMILES OC(=O)C1CCCN1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000104 (Azetidine-3-carboxylic acid \| CHEMBL310435) Show SMILES OC(=O)C1CNC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000109 ((2R)-2-aminopropanoic acid \| (R)-2-aminopropanoic ...) Show SMILES C[C@@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	9.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1 of rat spinal cord ...				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000106 (4-CARBOXYPIPERIDINE \| CHEMBL279998 \| Piperidine-4-...) Show SMILES OC(=O)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	PubMed	n/a	n/a	9.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000099 ((2S)-2-aminopropanoic acid \| (S)-2-aminopropanoic ...) Show SMILES C[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000103 (2,5-Dihydro-1H-pyrrole-2-carboxylic acid \| CHEMBL3...) Show SMILES OC(=O)C1NCC=C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000108 (CHEMBL33592 \| azetidine-2-carboxylic acid) Show SMILES OC(=O)C1CCN1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.99E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000100 ((-)-(S)-proline \| (-)-2-pyrrolidinecarboxylic acid...) Show SMILES OC(=O)[C@@H]1CCCN1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	4.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate-NMDA (RAT)	BDBM50000107 (1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic ...) Show SMILES CN1CCC=C(C1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound required to inhibit [3H]-strychnine binding to N-methyl-D-aspartate glutamate receptor 1				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%