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PubMed code 1319493

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma


(HUMAN)
BDBM50037480
PNG
((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)
Show SMILES CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21
Show InChI InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1
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0.290n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000776
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperaz...)
Show SMILES CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C15H22Cl2N2/c1-2-6-18-8-10-19(11-9-18)7-5-13-3-4-14(16)15(17)12-13/h3-4,12H,2,5-11H2,1H3
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0.310n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000069
PNG
(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3
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0.340n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000773
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...)
Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2
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0.390n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000769
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(5-fluoro-pent...)
Show SMILES FCCCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-9-22-12-10-21(11-13-22)8-3-1-2-7-20/h4-5,14H,1-3,6-13H2
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0.520n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000771
PNG
(CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethy...)
Show SMILES CN(CCN1CCCC1)CCc1cc(Cl)c(Cl)cc1I
Show InChI InChI=1S/C15H21Cl2IN2/c1-19(8-9-20-5-2-3-6-20)7-4-12-10-13(16)14(17)11-15(12)18/h10-11H,2-9H2,1H3
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0.540n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000769
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(5-fluoro-pent...)
Show SMILES FCCCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-9-22-12-10-21(11-13-22)8-3-1-2-7-20/h4-5,14H,1-3,6-13H2
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0.860n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000774
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-iodo-propyl...)
Show SMILES Clc1ccc(CCN2CCN(CCCI)CC2)cc1Cl
Show InChI InChI=1S/C15H21Cl2IN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2
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1.20n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000771
PNG
(CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethy...)
Show SMILES CN(CCN1CCCC1)CCc1cc(Cl)c(Cl)cc1I
Show InChI InChI=1S/C15H21Cl2IN2/c1-19(8-9-20-5-2-3-6-20)7-4-12-10-13(16)14(17)11-15(12)18/h10-11H,2-9H2,1H3
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1.20n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000774
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-iodo-propyl...)
Show SMILES Clc1ccc(CCN2CCN(CCCI)CC2)cc1Cl
Show InChI InChI=1S/C15H21Cl2IN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2
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1.30n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000772
PNG
(CHEMBL70861 | [2-(3,4-Dichloro-phenyl)-ethyl]-(3-f...)
Show SMILES FCCCN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-11-22(10-3-7-20)13-12-21-8-1-2-9-21/h4-5,14H,1-3,6-13H2
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4.20n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000773
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...)
Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2
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4.20n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000772
PNG
(CHEMBL70861 | [2-(3,4-Dichloro-phenyl)-ethyl]-(3-f...)
Show SMILES FCCCN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-11-22(10-3-7-20)13-12-21-8-1-2-9-21/h4-5,14H,1-3,6-13H2
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5.10n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50037480
PNG
((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)
Show SMILES CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21
Show InChI InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1
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11n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-pentazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000770
PNG
(3-(5-Fluoro-pentyl)-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCCCCF
Show InChI InChI=1S/C19H28FNO/c1-14-18-12-15-6-7-16(22)13-17(15)19(14,2)8-11-21(18)10-5-3-4-9-20/h6-7,13-14,18,22H,3-5,8-12H2,1-2H3/t14-,18+,19-/m0/s1
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74n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Sigma


(HUMAN)
BDBM50000770
PNG
(3-(5-Fluoro-pentyl)-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Show SMILES C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCCCCF
Show InChI InChI=1S/C19H28FNO/c1-14-18-12-15-6-7-16(22)13-17(15)19(14,2)8-11-21(18)10-5-3-4-9-20/h6-7,13-14,18,22H,3-5,8-12H2,1-2H3/t14-,18+,19-/m0/s1
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74n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50000069
PNG
(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3
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1.11E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50000771
PNG
(CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethy...)
Show SMILES CN(CCN1CCCC1)CCc1cc(Cl)c(Cl)cc1I
Show InChI InChI=1S/C15H21Cl2IN2/c1-19(8-9-20-5-2-3-6-20)7-4-12-10-13(16)14(17)11-15(12)18/h10-11H,2-9H2,1H3
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1.31E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
mu/kappa opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50037480
PNG
((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)
Show SMILES CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21
Show InChI InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1
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1.99E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa from guinea pig brain, using [3H](-)-bremazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50037480
PNG
((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)
Show SMILES CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21
Show InChI InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1
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2.53E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50000776
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperaz...)
Show SMILES CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C15H22Cl2N2/c1-2-6-18-8-10-19(11-9-18)7-5-13-3-4-14(16)15(17)12-13/h3-4,12H,2,5-11H2,1H3
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2.90E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50000772
PNG
(CHEMBL70861 | [2-(3,4-Dichloro-phenyl)-ethyl]-(3-f...)
Show SMILES FCCCN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-11-22(10-3-7-20)13-12-21-8-1-2-9-21/h4-5,14H,1-3,6-13H2
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3.11E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against Dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C)


(Rattus norvegicus (Rat))
BDBM50037480
PNG
((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...)
Show SMILES CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21
Show InChI InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1
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9.04E+3n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against PCP receptor from guinea pig brain, using [3H]TCP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
mu/kappa opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50000772
PNG
(CHEMBL70861 | [2-(3,4-Dichloro-phenyl)-ethyl]-(3-f...)
Show SMILES FCCCN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-11-22(10-3-7-20)13-12-21-8-1-2-9-21/h4-5,14H,1-3,6-13H2
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1.05E+4n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against Opioid receptor kappa 1 from guinea pig brain, using [3H](-)-bremazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50000773
PNG
(1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-prop...)
Show SMILES FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2
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1.20E+4n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against dopamine receptor D2 from rat brain, using [3H](-)-sulpiride as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
mu/kappa opioid receptor


(Cavia porcellus (domestic guinea pig))
BDBM50000771
PNG
(CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethy...)
Show SMILES CN(CCN1CCCC1)CCc1cc(Cl)c(Cl)cc1I
Show InChI InChI=1S/C15H21Cl2IN2/c1-19(8-9-20-5-2-3-6-20)7-4-12-10-13(16)14(17)11-15(12)18/h10-11H,2-9H2,1H3
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1.85E+4n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against Opioid receptor kappa 1 from guinea pig brain, using [3H](-)-bremazocine as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C)


(Rattus norvegicus (Rat))
BDBM50000771
PNG
(CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethy...)
Show SMILES CN(CCN1CCCC1)CCc1cc(Cl)c(Cl)cc1I
Show InChI InChI=1S/C15H21Cl2IN2/c1-19(8-9-20-5-2-3-6-20)7-4-12-10-13(16)14(17)11-15(12)18/h10-11H,2-9H2,1H3
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2.49E+4n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity against phencyclidine (PCP) receptor from guinea pig brain, using [3H]TCP as radioligand.


J Med Chem 35: 2221-30 (1992)


Article DOI: 10.1021/jm00090a012
BindingDB Entry DOI: 10.7270/Q24B31ZD
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%