Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001224![]() ((8-Methoxy-quinolin-4-yl)-o-tolyl-amine | CHEMBL11...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001235![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-propan-...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001259![]() (4-o-Tolylamino-quinoline-3-carboxylic acid ethyl e...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001247![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of gastric H+/K+ ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001240![]() (1-(4-o-Tolylamino-quinolin-3-yl)-butan-1-one | CHE...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001254![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-butan-1...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001232![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-2-methy...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001239![]() (CHEMBL116272 | Cyclobutyl-(8-methoxy-4-o-tolylamin...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001257![]() (CHEMBL545745 | Quinolin-4-yl-o-tolyl-amine; hydroc...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001258![]() (CHEMBL326168 | Cyclopentyl-(8-methoxy-4-o-tolylami...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001237![]() (2-Ethyl-1-(8-methoxy-4-o-tolylamino-quinolin-3-yl)...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001243![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-2,2-dim...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001230![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-hexan-1...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001227![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001253![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001234![]() (8-Methoxy-4-phenylamino-quinoline-3-carboxylic aci...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001255![]() (CHEMBL115240 | Cyclohexyl-(8-methoxy-4-o-tolylamin...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001231![]() (1-(8-Methoxy-4-phenylamino-quinolin-3-yl)-butan-1-...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001236![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-ethanon...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001226![]() ((3-Propylsulfanyl-quinolin-4-yl)-o-tolyl-amine | C...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001244![]() ((8-Methoxy-3-methyl-quinolin-4-yl)-o-tolyl-amine |...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001242![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of gastric H+/K+ ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001225![]() ((8-Methoxy-3-propyl-quinolin-4-yl)-o-tolyl-amine(0...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001249![]() ((8-Methoxy-4-o-tolylamino-quinolin-3-yl)-methanol ...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of gastric H+/K+ ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001246![]() (CHEMBL543879 | [3-(1-Methyl-1H-tetrazol-5-yl)-quin...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50406683![]() (CHEMBL2111758) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001238![]() ((3-Bromo-quinolin-4-yl)-o-tolyl-amine | CHEMBL1152...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001229![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of gastric H+/K+ ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001233![]() ((8-Methoxy-4-o-tolylamino-quinolin-3-yl)-phenyl-me...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001223![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-ethanon...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001256![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001250![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-ethanol...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50368384![]() (CHEMBL1203150) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001241![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001245![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001251![]() (1-(8-Methoxy-4-o-tolylamino-quinolin-3-yl)-butan-1...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001228![]() (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium-transporting ATPase (Sus scrofa (Pig)) | BDBM50001248![]() (8-Methoxy-4-(methyl-phenyl-amino)-quinoline-3-carb...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL | Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase | J Med Chem 35: 3413-22 (1992) Article DOI: 10.1021/jm00096a018 BindingDB Entry DOI: 10.7270/Q2CN74J2 | |||||||||||
More data for this Ligand-Target Pair |