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PubMed code 1375964

Compile data set for download or QSAR
Found 112 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002514
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1ccc2cc(OS(O)(=O)=O)ccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O13S/c1-46(2,3)65-45(61)53-37(24-31-26-49-34-14-8-7-13-33(31)34)43(59)50-35(42(58)52-38(25-39(54)55)44(60)51-36(40(47)56)21-27-11-5-4-6-12-27)15-9-10-20-48-41(57)30-17-16-29-23-32(66-67(62,63)64)19-18-28(29)22-30/h4-8,11-14,16-19,22-23,26,35-38,49H,9-10,15,20-21,24-25H2,1-3H3,(H2,47,56)(H,48,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)(H,62,63,64)/t35-,36-,37-,38-/m0/s1
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n/an/a 2.90n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002523
PNG
(3-{6-[(6-Acetoxy-naphthalene-2-carbonyl)-amino]-2-...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)c1ccc2cc(OC(C)=O)ccc2c1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C49H57N7O11/c1-29(57)66-35-21-20-31-24-33(19-18-32(31)25-35)44(61)51-22-12-11-17-38(45(62)54-40(27-42(58)59)47(64)56(5)41(43(50)60)23-30-13-7-6-8-14-30)53-46(63)39(55-48(65)67-49(2,3)4)26-34-28-52-37-16-10-9-15-36(34)37/h6-10,13-16,18-21,24-25,28,38-41,52H,11-12,17,22-23,26-27H2,1-5H3,(H2,50,60)(H,51,61)(H,53,63)(H,54,62)(H,55,65)(H,58,59)/t38-,39-,40-,41-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002528
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)c1ccc2cc(O)ccc2c1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C47H55N7O10/c1-47(2,3)64-46(63)53-37(25-32-27-50-35-15-9-8-14-34(32)35)44(61)51-36(16-10-11-21-49-42(59)31-18-17-30-24-33(55)20-19-29(30)23-31)43(60)52-38(26-40(56)57)45(62)54(4)39(41(48)58)22-28-12-6-5-7-13-28/h5-9,12-15,17-20,23-24,27,36-39,50,55H,10-11,16,21-22,25-26H2,1-4H3,(H2,48,58)(H,49,59)(H,51,61)(H,52,60)(H,53,63)(H,56,57)/t36-,37-,38-,39-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002485
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H55N7O10/c1-45(2,3)62-44(61)51-35(25-30-27-48-33-15-9-8-14-32(30)33)42(59)49-34(16-10-11-23-47-38(54)22-19-28-17-20-31(53)21-18-28)41(58)50-36(26-39(55)56)43(60)52(4)37(40(46)57)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,48,53H,10-11,16,23-26H2,1-4H3,(H2,46,57)(H,47,54)(H,49,59)(H,50,58)(H,51,61)(H,55,56)/b22-19+/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002529
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1ccc2cc(O)ccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O10/c1-46(2,3)63-45(62)53-37(24-31-26-49-34-14-8-7-13-33(31)34)43(60)50-35(15-9-10-20-48-41(58)30-17-16-29-23-32(54)19-18-28(29)22-30)42(59)52-38(25-39(55)56)44(61)51-36(40(47)57)21-27-11-5-4-6-12-27/h4-8,11-14,16-19,22-23,26,35-38,49,54H,9-10,15,20-21,24-25H2,1-3H3,(H2,47,57)(H,48,58)(H,50,60)(H,51,61)(H,52,59)(H,53,62)(H,55,56)/t35-,36-,37-,38-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002498
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cnc2cccc(O)c2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H52N8O10/c1-45(2,3)63-44(62)53-35(22-27-24-48-31-15-8-7-14-29(27)31)42(60)50-33(16-9-10-19-47-40(58)28-21-30-32(49-25-28)17-11-18-37(30)54)41(59)52-36(23-38(55)56)43(61)51-34(39(46)57)20-26-12-5-4-6-13-26/h4-8,11-15,17-18,21,24-25,33-36,48,54H,9-10,16,19-20,22-23H2,1-3H3,(H2,46,57)(H,47,58)(H,50,60)(H,51,61)(H,52,59)(H,53,62)(H,55,56)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002516
PNG
(3-{6-[(6-Acetoxy-naphthalene-2-carbonyl)-amino]-2-...)
Show SMILES CC(=O)Oc1ccc2cc(ccc2c1)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C48H55N7O11/c1-28(56)65-34-20-19-30-23-32(18-17-31(30)24-34)43(60)50-21-11-10-16-37(44(61)54-40(26-41(57)58)46(63)53-38(42(49)59)22-29-12-6-5-7-13-29)52-45(62)39(55-47(64)66-48(2,3)4)25-33-27-51-36-15-9-8-14-35(33)36/h5-9,12-15,17-20,23-24,27,37-40,51H,10-11,16,21-22,25-26H2,1-4H3,(H2,49,59)(H,50,60)(H,52,62)(H,53,63)(H,54,61)(H,55,64)(H,57,58)/t37-,38-,39-,40-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002490
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(OS(O)(=O)=O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(57)48-33(15-9-10-22-46-37(52)21-18-27-16-19-30(20-17-27)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,47H,9-10,15,22-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002504
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1ccc2ccccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O9/c1-46(2,3)62-45(61)53-37(25-32-27-49-34-18-10-9-17-33(32)34)43(59)50-35(19-11-12-22-48-41(57)31-21-20-29-15-7-8-16-30(29)24-31)42(58)52-38(26-39(54)55)44(60)51-36(40(47)56)23-28-13-5-4-6-14-28/h4-10,13-18,20-21,24,27,35-38,49H,11-12,19,22-23,25-26H2,1-3H3,(H2,47,56)(H,48,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t35-,36-,37-,38-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002484
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cc2cc(O)ccc2[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52N8O10/c1-44(2,3)62-43(61)52-35(22-27-24-47-31-14-8-7-13-29(27)31)41(59)49-32(15-9-10-18-46-39(57)34-21-26-20-28(53)16-17-30(26)48-34)40(58)51-36(23-37(54)55)42(60)50-33(38(45)56)19-25-11-5-4-6-12-25/h4-8,11-14,16-17,20-21,24,32-33,35-36,47-48,53H,9-10,15,18-19,22-23H2,1-3H3,(H2,45,56)(H,46,57)(H,49,59)(H,50,60)(H,51,58)(H,52,61)(H,54,55)/t32-,33-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002519
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H54ClN7O9/c1-45(2,3)62-44(61)52-35(25-30-27-49-33-15-9-8-14-32(30)33)42(59)50-34(16-10-11-23-48-38(54)22-19-28-17-20-31(46)21-18-28)41(58)51-36(26-39(55)56)43(60)53(4)37(40(47)57)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,49H,10-11,16,23-26H2,1-4H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,58)(H,52,61)(H,55,56)/b22-19+/t34-,35-,36-,37-/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002521
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(58)48-33(15-9-10-22-46-37(53)21-18-27-16-19-30(52)20-17-27)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,47,52H,9-10,15,22-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002511
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)C=Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H54N8O9/c1-46(2,3)63-45(62)54-37(24-30-27-50-34-18-10-8-16-32(30)34)43(60)51-35(19-11-12-22-48-39(55)21-20-29-26-49-33-17-9-7-15-31(29)33)42(59)53-38(25-40(56)57)44(61)52-36(41(47)58)23-28-13-5-4-6-14-28/h4-10,13-18,20-21,26-27,35-38,49-50H,11-12,19,22-25H2,1-3H3,(H2,47,58)(H,48,55)(H,51,60)(H,52,61)(H,53,59)(H,54,62)(H,56,57)/b21-20+/t35-,36-,37-,38-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002483
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)C=Cc1cccnc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C43H52N8O9/c1-43(2,3)60-42(59)51-34(23-29-26-47-31-16-8-7-15-30(29)31)40(57)48-32(17-9-10-21-46-36(52)19-18-28-14-11-20-45-25-28)39(56)50-35(24-37(53)54)41(58)49-33(38(44)55)22-27-12-5-4-6-13-27/h4-8,11-16,18-20,25-26,32-35,47H,9-10,17,21-24H2,1-3H3,(H2,44,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/b19-18+/t32-,33-,34-,35-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002481
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1cccc(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(58)48-33(18-9-10-21-46-37(53)20-19-28-14-11-15-30(52)22-28)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-27-12-5-4-6-13-27/h4-8,11-17,19-20,22,26,33-36,47,52H,9-10,18,21,23-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b20-19-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002501
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H55N7O13S/c1-45(2,3)64-44(60)51-35(25-30-27-48-33-15-9-8-14-32(30)33)42(58)49-34(16-10-11-23-47-38(53)22-19-28-17-20-31(21-18-28)65-66(61,62)63)41(57)50-36(26-39(54)55)43(59)52(4)37(40(46)56)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,48H,10-11,16,23-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,57)(H,51,60)(H,54,55)(H,61,62,63)/b22-19+/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002477
PNG
((S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H...)
Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C34H44N6O8S/c1-34(2,3)48-33(47)40-26(17-21-19-36-23-13-9-8-12-22(21)23)31(45)37-24(14-15-49-4)30(44)39-27(18-28(41)42)32(46)38-25(29(35)43)16-20-10-6-5-7-11-20/h5-13,19,24-27,36H,14-18H2,1-4H3,(H2,35,43)(H,37,45)(H,38,46)(H,39,44)(H,40,47)(H,41,42)/t24-,25-,26-,27-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002482
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1cccnc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H54N8O9/c1-44(2,3)61-43(60)51-34(24-30-27-48-32-17-9-8-16-31(30)32)41(58)49-33(18-10-11-22-47-37(53)20-19-29-15-12-21-46-26-29)40(57)50-35(25-38(54)55)42(59)52(4)36(39(45)56)23-28-13-6-5-7-14-28/h5-9,12-17,19-21,26-27,33-36,48H,10-11,18,22-25H2,1-4H3,(H2,45,56)(H,47,53)(H,49,58)(H,50,57)(H,51,60)(H,54,55)/b20-19+/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002496
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H55N7O10/c1-45(2,3)62-44(60)52-36(25-30-27-48-33-15-9-8-14-32(30)33)42(58)49-34(16-10-11-23-47-38(53)22-19-28-17-20-31(61-4)21-18-28)41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,48H,10-11,16,23-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b22-19-/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002499
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)CCc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H57N7O10/c1-45(2,3)62-44(61)51-35(25-30-27-48-33-15-9-8-14-32(30)33)42(59)49-34(16-10-11-23-47-38(54)22-19-28-17-20-31(53)21-18-28)41(58)50-36(26-39(55)56)43(60)52(4)37(40(46)57)24-29-12-6-5-7-13-29/h5-9,12-15,17-18,20-21,27,34-37,48,53H,10-11,16,19,22-26H2,1-4H3,(H2,46,57)(H,47,54)(H,49,59)(H,50,58)(H,51,61)(H,55,56)/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002524
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cnc2ccccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H52N8O9/c1-45(2,3)62-44(61)53-36(23-29-25-49-33-18-10-8-16-31(29)33)42(59)50-34(19-11-12-20-47-40(57)30-22-28-15-7-9-17-32(28)48-26-30)41(58)52-37(24-38(54)55)43(60)51-35(39(46)56)21-27-13-5-4-6-14-27/h4-10,13-18,22,25-26,34-37,49H,11-12,19-21,23-24H2,1-3H3,(H2,46,56)(H,47,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002513
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(O)c(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O11/c1-44(2,3)62-43(61)51-33(23-28-25-47-30-14-8-7-13-29(28)30)41(59)48-31(15-9-10-20-46-37(54)19-17-27-16-18-35(52)36(53)22-27)40(58)50-34(24-38(55)56)42(60)49-32(39(45)57)21-26-11-5-4-6-12-26/h4-8,11-14,16-19,22,25,31-34,47,52-53H,9-10,15,20-21,23-24H2,1-3H3,(H2,45,57)(H,46,54)(H,48,59)(H,49,60)(H,50,58)(H,51,61)(H,55,56)/b19-17-/t31-,32-,33-,34-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002502
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c(OC)c1
Show InChI InChI=1S/C46H57N7O11/c1-46(2,3)64-45(61)53-36(24-30-27-49-33-16-10-9-15-32(30)33)43(59)50-34(17-11-12-22-48-39(54)21-19-29-18-20-31(62-4)25-38(29)63-5)42(58)52-37(26-40(55)56)44(60)51-35(41(47)57)23-28-13-7-6-8-14-28/h6-10,13-16,18-21,25,27,34-37,49H,11-12,17,22-24,26H2,1-5H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b21-19-/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002506
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1cccc(OS(O)(=O)=O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(57)48-33(18-9-10-21-46-37(52)20-19-28-14-11-15-30(22-28)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-27-12-5-4-6-13-27/h4-8,11-17,19-20,22,26,33-36,47H,9-10,18,21,23-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/b20-19-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002510
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52N8O9/c1-44(2,3)61-43(60)52-35(23-28-25-47-31-18-10-8-16-29(28)31)41(58)49-32(19-11-12-20-46-39(56)34-22-27-15-7-9-17-30(27)48-34)40(57)51-36(24-37(53)54)42(59)50-33(38(45)55)21-26-13-5-4-6-14-26/h4-10,13-18,22,25,32-33,35-36,47-48H,11-12,19-21,23-24H2,1-3H3,(H2,45,55)(H,46,56)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,53,54)/t32-,33-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002480
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1OC
Show InChI InChI=1S/C46H57N7O11/c1-46(2,3)64-45(61)53-35(25-30-27-49-32-16-10-9-15-31(30)32)43(59)50-33(17-11-12-22-48-39(54)21-19-29-18-20-37(62-4)38(24-29)63-5)42(58)52-36(26-40(55)56)44(60)51-34(41(47)57)23-28-13-7-6-8-14-28/h6-10,13-16,18-21,24,27,33-36,49H,11-12,17,22-23,25-26H2,1-5H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b21-19-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002526
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Cl)c(Cl)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H51Cl2N7O9/c1-44(2,3)62-43(61)53-35(23-28-25-49-32-14-8-7-13-29(28)32)41(59)50-33(15-9-10-20-48-37(54)19-17-27-16-18-30(45)31(46)21-27)40(58)52-36(24-38(55)56)42(60)51-34(39(47)57)22-26-11-5-4-6-12-26/h4-8,11-14,16-19,21,25,33-36,49H,9-10,15,20,22-24H2,1-3H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b19-17-/t33-,34-,35-,36-/m0/s1
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n/an/a 49n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002500
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)C=Cc1cccs1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C42H51N7O9S/c1-42(2,3)58-41(57)49-33(23-27-25-45-30-16-8-7-15-29(27)30)39(55)46-31(17-9-10-20-44-35(50)19-18-28-14-11-21-59-28)38(54)48-34(24-36(51)52)40(56)47-32(37(43)53)22-26-12-5-4-6-13-26/h4-8,11-16,18-19,21,25,31-34,45H,9-10,17,20,22-24H2,1-3H3,(H2,43,53)(H,44,50)(H,46,55)(H,47,56)(H,48,54)(H,49,57)(H,51,52)/b19-18+/t31-,32-,33-,34-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002486
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H54N8O10/c1-45(2,3)63-44(61)53-36(23-28-25-48-32-15-9-8-14-30(28)32)42(59)50-33(16-10-11-19-47-40(57)35-22-27-21-29(62-4)17-18-31(27)49-35)41(58)52-37(24-38(54)55)43(60)51-34(39(46)56)20-26-12-6-5-7-13-26/h5-9,12-15,17-18,21-22,25,33-34,36-37,48-49H,10-11,16,19-20,23-24H2,1-4H3,(H2,46,56)(H,47,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t33-,34-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002479
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O9/c1-44(2,3)60-43(59)51-35(25-30-27-47-32-19-11-10-18-31(30)32)41(57)48-33(20-12-13-23-46-37(52)22-21-28-14-6-4-7-15-28)40(56)50-36(26-38(53)54)42(58)49-34(39(45)55)24-29-16-8-5-9-17-29/h4-11,14-19,21-22,27,33-36,47H,12-13,20,23-26H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/b22-21-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002494
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cccc2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O9/c1-46(2,3)62-45(61)53-37(25-30-27-49-34-21-10-9-19-32(30)34)43(59)50-35(22-11-12-23-48-41(57)33-20-13-17-29-16-7-8-18-31(29)33)42(58)52-38(26-39(54)55)44(60)51-36(40(47)56)24-28-14-5-4-6-15-28/h4-10,13-21,27,35-38,49H,11-12,22-26H2,1-3H3,(H2,47,56)(H,48,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t35-,36-,37-,38-/m0/s1
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n/an/a 57n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002475
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(cc1)[N+]([O-])=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52N8O11/c1-44(2,3)63-43(60)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(58)48-33(15-9-10-22-46-37(53)21-18-27-16-19-30(20-17-27)52(61)62)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,47H,9-10,15,22-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002525
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(F)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52FN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,48H,9-10,15,22-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002491
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES Cc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H55N7O9/c1-28-17-19-29(20-18-28)21-22-38(53)47-23-11-10-16-34(41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-30-12-6-5-7-13-30)49-42(58)36(52-44(60)61-45(2,3)4)25-31-27-48-33-15-9-8-14-32(31)33/h5-9,12-15,17-22,27,34-37,48H,10-11,16,23-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b22-21-/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002508
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52ClN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,48H,9-10,15,22-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002493
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(OS(O)(=O)=O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(57)48-33(15-9-10-22-46-37(52)21-18-27-16-19-30(20-17-27)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,47H,9-10,15,18,21-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002483
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)C=Cc1cccnc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C43H52N8O9/c1-43(2,3)60-42(59)51-34(23-29-26-47-31-16-8-7-15-30(29)31)40(57)48-32(17-9-10-21-46-36(52)19-18-28-14-11-20-45-25-28)39(56)50-35(24-37(53)54)41(58)49-33(38(44)55)22-27-12-5-4-6-13-27/h4-8,11-16,18-20,25-26,32-35,47H,9-10,17,21-24H2,1-3H3,(H2,44,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/b19-18+/t32-,33-,34-,35-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002487
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccccc1O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O10/c1-44(2,3)61-43(60)51-34(24-29-26-47-31-17-9-8-16-30(29)31)41(58)48-32(18-11-12-22-46-37(53)21-20-28-15-7-10-19-36(28)52)40(57)50-35(25-38(54)55)42(59)49-33(39(45)56)23-27-13-5-4-6-14-27/h4-10,13-17,19-21,26,32-35,47,52H,11-12,18,22-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b21-20-/t32-,33-,34-,35-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002517
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H51ClN8O9/c1-44(2,3)62-43(61)53-35(22-27-24-48-31-14-8-7-13-29(27)31)41(59)50-32(15-9-10-18-47-39(57)34-21-26-20-28(45)16-17-30(26)49-34)40(58)52-36(23-37(54)55)42(60)51-33(38(46)56)19-25-11-5-4-6-12-25/h4-8,11-14,16-17,20-21,24,32-33,35-36,48-49H,9-10,15,18-19,22-23H2,1-3H3,(H2,46,56)(H,47,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t32-,33-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002474
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN(C)c1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C46H58N8O9/c1-46(2,3)63-45(62)53-37(26-31-28-49-34-16-10-9-15-33(31)34)43(60)50-35(17-11-12-24-48-39(55)23-20-29-18-21-32(22-19-29)54(4)5)42(59)52-38(27-40(56)57)44(61)51-36(41(47)58)25-30-13-7-6-8-14-30/h6-10,13-16,18-23,28,35-38,49H,11-12,17,24-27H2,1-5H3,(H2,47,58)(H,48,55)(H,50,60)(H,51,61)(H,52,59)(H,53,62)(H,56,57)/b23-20-/t35-,36-,37-,38-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002520
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(58)48-33(15-9-10-22-46-37(53)21-18-27-16-19-30(52)20-17-27)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,47,52H,9-10,15,18,21-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002482
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1cccnc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H54N8O9/c1-44(2,3)61-43(60)51-34(24-30-27-48-32-17-9-8-16-31(30)32)41(58)49-33(18-10-11-22-47-37(53)20-19-29-15-12-21-46-26-29)40(57)50-35(25-38(54)55)42(59)52(4)36(39(45)56)23-28-13-6-5-7-14-28/h5-9,12-17,19-21,26-27,33-36,48H,10-11,18,22-25H2,1-4H3,(H2,45,56)(H,47,53)(H,49,58)(H,50,57)(H,51,60)(H,54,55)/b20-19+/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002497
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Cl)cc1Cl)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H51Cl2N7O9/c1-44(2,3)62-43(61)53-35(22-28-25-49-32-14-8-7-13-30(28)32)41(59)50-33(15-9-10-20-48-37(54)19-17-27-16-18-29(45)23-31(27)46)40(58)52-36(24-38(55)56)42(60)51-34(39(47)57)21-26-11-5-4-6-12-26/h4-8,11-14,16-19,23,25,33-36,49H,9-10,15,20-22,24H2,1-3H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b19-17-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002495
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H57N7O10/c1-45(2,3)62-44(60)52-36(25-30-27-48-33-15-9-8-14-32(30)33)42(58)49-34(16-10-11-23-47-38(53)22-19-28-17-20-31(61-4)21-18-28)41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-29-12-6-5-7-13-29/h5-9,12-15,17-18,20-21,27,34-37,48H,10-11,16,19,22-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002509
PNG
(3-{6-[3-(4-Bromo-phenyl)-acryloylamino]-2-[2-tert-...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Br)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52BrN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,48H,9-10,15,22-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002478
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(O)c(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O11/c1-44(2,3)62-43(61)51-33(23-28-25-47-30-14-8-7-13-29(28)30)41(59)48-31(15-9-10-20-46-37(54)19-17-27-16-18-35(52)36(53)22-27)40(58)50-34(24-38(55)56)42(60)49-32(39(45)57)21-26-11-5-4-6-12-26/h4-8,11-14,16,18,22,25,31-34,47,52-53H,9-10,15,17,19-21,23-24H2,1-3H3,(H2,45,57)(H,46,54)(H,48,59)(H,49,60)(H,50,58)(H,51,61)(H,55,56)/t31-,32-,33-,34-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002489
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1cccc(OS(O)(=O)=O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(57)48-33(18-9-10-21-46-37(52)20-19-28-14-11-15-30(22-28)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-27-12-5-4-6-13-27/h4-8,11-17,22,26,33-36,47H,9-10,18-21,23-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002524
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cnc2ccccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H52N8O9/c1-45(2,3)62-44(61)53-36(23-29-25-49-33-18-10-8-16-31(29)33)42(59)50-34(19-11-12-20-47-40(57)30-22-28-15-7-9-17-32(28)48-26-30)41(58)52-37(24-38(54)55)43(60)51-35(39(46)56)21-27-13-5-4-6-14-27/h4-10,13-18,22,25-26,34-37,49H,11-12,19-21,23-24H2,1-3H3,(H2,46,56)(H,47,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002487
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccccc1O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O10/c1-44(2,3)61-43(60)51-34(24-29-26-47-31-17-9-8-16-30(29)31)41(58)48-32(18-11-12-22-46-37(53)21-20-28-15-7-10-19-36(28)52)40(57)50-35(25-38(54)55)42(59)49-33(39(45)56)23-27-13-5-4-6-14-27/h4-10,13-17,19-21,26,32-35,47,52H,11-12,18,22-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b21-20-/t32-,33-,34-,35-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002503
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H52F3N7O9/c1-44(2,3)64-43(63)55-35(24-29-26-51-32-14-8-7-13-31(29)32)41(61)52-33(15-9-10-22-50-37(56)21-18-27-16-19-30(20-17-27)45(46,47)48)40(60)54-36(25-38(57)58)42(62)53-34(39(49)59)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,51H,9-10,15,22-25H2,1-3H3,(H2,49,59)(H,50,56)(H,52,61)(H,53,62)(H,54,60)(H,55,63)(H,57,58)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002506
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1cccc(OS(O)(=O)=O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(57)48-33(18-9-10-21-46-37(52)20-19-28-14-11-15-30(22-28)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-27-12-5-4-6-13-27/h4-8,11-17,19-20,22,26,33-36,47H,9-10,18,21,23-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/b20-19-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002527
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(F)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H54FN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,48H,9-10,15,18,21-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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n/an/a 250n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002505
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES Cc1ccc(CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H57N7O9/c1-28-17-19-29(20-18-28)21-22-38(53)47-23-11-10-16-34(41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-30-12-6-5-7-13-30)49-42(58)36(52-44(60)61-45(2,3)4)25-31-27-48-33-15-9-8-14-32(31)33/h5-9,12-15,17-20,27,34-37,48H,10-11,16,21-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002514
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1ccc2cc(OS(O)(=O)=O)ccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O13S/c1-46(2,3)65-45(61)53-37(24-31-26-49-34-14-8-7-13-33(31)34)43(59)50-35(42(58)52-38(25-39(54)55)44(60)51-36(40(47)56)21-27-11-5-4-6-12-27)15-9-10-20-48-41(57)30-17-16-29-23-32(66-67(62,63)64)19-18-28(29)22-30/h4-8,11-14,16-19,22-23,26,35-38,49H,9-10,15,20-21,24-25H2,1-3H3,(H2,47,56)(H,48,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)(H,62,63,64)/t35-,36-,37-,38-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002522
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O9/c1-44(2,3)60-43(59)51-35(25-30-27-47-32-19-11-10-18-31(30)32)41(57)48-33(20-12-13-23-46-37(52)22-21-28-14-6-4-7-15-28)40(56)50-36(26-38(53)54)42(58)49-34(39(45)55)24-29-16-8-5-9-17-29/h4-11,14-19,27,33-36,47H,12-13,20-26H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002512
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCC1CCCCC1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H61N7O9/c1-44(2,3)60-43(59)51-35(25-30-27-47-32-19-11-10-18-31(30)32)41(57)48-33(20-12-13-23-46-37(52)22-21-28-14-6-4-7-15-28)40(56)50-36(26-38(53)54)42(58)49-34(39(45)55)24-29-16-8-5-9-17-29/h5,8-11,16-19,27-28,33-36,47H,4,6-7,12-15,20-26H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002518
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H54F3N7O9/c1-44(2,3)64-43(63)55-35(24-29-26-51-32-14-8-7-13-31(29)32)41(61)52-33(15-9-10-22-50-37(56)21-18-27-16-19-30(20-17-27)45(46,47)48)40(60)54-36(25-38(57)58)42(62)53-34(39(49)59)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,51H,9-10,15,18,21-25H2,1-3H3,(H2,49,59)(H,50,56)(H,52,61)(H,53,62)(H,54,60)(H,55,63)(H,57,58)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002492
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1cccc(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(58)48-33(18-9-10-21-46-37(53)20-19-28-14-11-15-30(52)22-28)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-27-12-5-4-6-13-27/h4-8,11-17,22,26,33-36,47,52H,9-10,18-21,23-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002476
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H54ClN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,48H,9-10,15,18,21-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002490
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(OS(O)(=O)=O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(57)48-33(15-9-10-22-46-37(52)21-18-27-16-19-30(20-17-27)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,47H,9-10,15,22-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/b21-18-/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002488
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C43H53N7O10/c1-43(2,3)60-42(59)50-34(23-28-25-46-31-14-8-7-13-30(28)31)40(57)47-32(15-9-10-20-45-36(52)22-27-16-18-29(51)19-17-27)39(56)49-35(24-37(53)54)41(58)48-33(38(44)55)21-26-11-5-4-6-12-26/h4-8,11-14,16-19,25,32-35,46,51H,9-10,15,20-24H2,1-3H3,(H2,44,55)(H,45,52)(H,47,57)(H,48,58)(H,49,56)(H,50,59)(H,53,54)/t32-,33-,34-,35-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002523
PNG
(3-{6-[(6-Acetoxy-naphthalene-2-carbonyl)-amino]-2-...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)c1ccc2cc(OC(C)=O)ccc2c1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C49H57N7O11/c1-29(57)66-35-21-20-31-24-33(19-18-32(31)25-35)44(61)51-22-12-11-17-38(45(62)54-40(27-42(58)59)47(64)56(5)41(43(50)60)23-30-13-7-6-8-14-30)53-46(63)39(55-48(65)67-49(2,3)4)26-34-28-52-37-16-10-9-15-36(34)37/h6-10,13-16,18-21,24-25,28,38-41,52H,11-12,17,22-23,26-27H2,1-5H3,(H2,50,60)(H,51,61)(H,53,63)(H,54,62)(H,55,65)(H,58,59)/t38-,39-,40-,41-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002498
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cnc2cccc(O)c2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H52N8O10/c1-45(2,3)63-44(62)53-35(22-27-24-48-31-15-8-7-14-29(27)31)42(60)50-33(16-9-10-19-47-40(58)28-21-30-32(49-25-28)17-11-18-37(30)54)41(59)52-36(23-38(55)56)43(61)51-34(39(46)57)20-26-12-5-4-6-13-26/h4-8,11-15,17-18,21,24-25,33-36,48,54H,9-10,16,19-20,22-23H2,1-3H3,(H2,46,57)(H,47,58)(H,50,60)(H,51,61)(H,52,59)(H,53,62)(H,55,56)/t33-,34-,35-,36-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002485
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H55N7O10/c1-45(2,3)62-44(61)51-35(25-30-27-48-33-15-9-8-14-32(30)33)42(59)49-34(16-10-11-23-47-38(54)22-19-28-17-20-31(53)21-18-28)41(58)50-36(26-39(55)56)43(60)52(4)37(40(46)57)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,48,53H,10-11,16,23-26H2,1-4H3,(H2,46,57)(H,47,54)(H,49,59)(H,50,58)(H,51,61)(H,55,56)/b22-19+/t34-,35-,36-,37-/m0/s1
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Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002528
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)c1ccc2cc(O)ccc2c1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C47H55N7O10/c1-47(2,3)64-46(63)53-37(25-32-27-50-35-15-9-8-14-34(32)35)44(61)51-36(16-10-11-21-49-42(59)31-18-17-30-24-33(55)20-19-29(30)23-31)43(60)52-38(26-40(56)57)45(62)54(4)39(41(48)58)22-28-12-6-5-7-13-28/h5-9,12-15,17-20,23-24,27,36-39,50,55H,10-11,16,21-22,25-26H2,1-4H3,(H2,48,58)(H,49,59)(H,51,61)(H,52,60)(H,53,63)(H,56,57)/t36-,37-,38-,39-/m0/s1
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n/an/a 730n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002521
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(58)48-33(15-9-10-22-46-37(53)21-18-27-16-19-30(52)20-17-27)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,47,52H,9-10,15,22-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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n/an/a 730n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002513
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(O)c(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O11/c1-44(2,3)62-43(61)51-33(23-28-25-47-30-14-8-7-13-29(28)30)41(59)48-31(15-9-10-20-46-37(54)19-17-27-16-18-35(52)36(53)22-27)40(58)50-34(24-38(55)56)42(60)49-32(39(45)57)21-26-11-5-4-6-12-26/h4-8,11-14,16-19,22,25,31-34,47,52-53H,9-10,15,20-21,23-24H2,1-3H3,(H2,45,57)(H,46,54)(H,48,59)(H,49,60)(H,50,58)(H,51,61)(H,55,56)/b19-17-/t31-,32-,33-,34-/m0/s1
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n/an/a 750n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002484
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cc2cc(O)ccc2[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52N8O10/c1-44(2,3)62-43(61)52-35(22-27-24-47-31-14-8-7-13-29(27)31)41(59)49-32(15-9-10-18-46-39(57)34-21-26-20-28(53)16-17-30(26)48-34)40(58)51-36(23-37(54)55)42(60)50-33(38(45)56)19-25-11-5-4-6-12-25/h4-8,11-14,16-17,20-21,24,32-33,35-36,47-48,53H,9-10,15,18-19,22-23H2,1-3H3,(H2,45,56)(H,46,57)(H,49,59)(H,50,60)(H,51,58)(H,52,61)(H,54,55)/t32-,33-,35-,36-/m0/s1
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n/an/a 830n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002500
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)C=Cc1cccs1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C42H51N7O9S/c1-42(2,3)58-41(57)49-33(23-27-25-45-30-16-8-7-15-29(27)30)39(55)46-31(17-9-10-20-44-35(50)19-18-28-14-11-21-59-28)38(54)48-34(24-36(51)52)40(56)47-32(37(43)53)22-26-12-5-4-6-13-26/h4-8,11-16,18-19,21,25,31-34,45H,9-10,17,20,22-24H2,1-3H3,(H2,43,53)(H,44,50)(H,46,55)(H,47,56)(H,48,54)(H,49,57)(H,51,52)/b19-18+/t31-,32-,33-,34-/m0/s1
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n/an/a 840n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002507
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCCc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H57N7O9/c1-45(2,3)61-44(60)52-36(26-31-28-48-33-21-11-10-20-32(31)33)42(58)49-34(22-12-13-24-47-38(53)23-14-19-29-15-6-4-7-16-29)41(57)51-37(27-39(54)55)43(59)50-35(40(46)56)25-30-17-8-5-9-18-30/h4-11,15-18,20-21,28,34-37,48H,12-14,19,22-27H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t34-,35-,36-,37-/m0/s1
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n/an/a 910n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002481
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1cccc(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(58)48-33(18-9-10-21-46-37(53)20-19-28-14-11-15-30(52)22-28)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-27-12-5-4-6-13-27/h4-8,11-17,19-20,22,26,33-36,47,52H,9-10,18,21,23-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b20-19-/t33-,34-,35-,36-/m0/s1
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n/an/a 970n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002501
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1ccc(OS(O)(=O)=O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H55N7O13S/c1-45(2,3)64-44(60)51-35(25-30-27-48-33-15-9-8-14-32(30)33)42(58)49-34(16-10-11-23-47-38(53)22-19-28-17-20-31(21-18-28)65-66(61,62)63)41(57)50-36(26-39(54)55)43(59)52(4)37(40(46)56)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,48H,10-11,16,23-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,57)(H,51,60)(H,54,55)(H,61,62,63)/b22-19+/t34-,35-,36-,37-/m0/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002488
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C43H53N7O10/c1-43(2,3)60-42(59)50-34(23-28-25-46-31-14-8-7-13-30(28)31)40(57)47-32(15-9-10-20-45-36(52)22-27-16-18-29(51)19-17-27)39(56)49-35(24-37(53)54)41(58)48-33(38(44)55)21-26-11-5-4-6-12-26/h4-8,11-14,16-19,25,32-35,46,51H,9-10,15,20-24H2,1-3H3,(H2,44,55)(H,45,52)(H,47,57)(H,48,58)(H,49,56)(H,50,59)(H,53,54)/t32-,33-,34-,35-/m0/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002529
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1ccc2cc(O)ccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O10/c1-46(2,3)63-45(62)53-37(24-31-26-49-34-14-8-7-13-33(31)34)43(60)50-35(15-9-10-20-48-41(58)30-17-16-29-23-32(54)19-18-28(29)22-30)42(59)52-38(25-39(55)56)44(61)51-36(40(47)57)21-27-11-5-4-6-12-27/h4-8,11-14,16-19,22-23,26,35-38,49,54H,9-10,15,20-21,24-25H2,1-3H3,(H2,47,57)(H,48,58)(H,50,60)(H,51,61)(H,52,59)(H,53,62)(H,55,56)/t35-,36-,37-,38-/m0/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002516
PNG
(3-{6-[(6-Acetoxy-naphthalene-2-carbonyl)-amino]-2-...)
Show SMILES CC(=O)Oc1ccc2cc(ccc2c1)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C48H55N7O11/c1-28(56)65-34-20-19-30-23-32(18-17-31(30)24-34)43(60)50-21-11-10-16-37(44(61)54-40(26-41(57)58)46(63)53-38(42(49)59)22-29-12-6-5-7-13-29)52-45(62)39(55-47(64)66-48(2,3)4)25-33-27-51-36-15-9-8-14-35(33)36/h5-9,12-15,17-20,23-24,27,37-40,51H,10-11,16,21-22,25-26H2,1-4H3,(H2,49,59)(H,50,60)(H,52,62)(H,53,63)(H,54,61)(H,55,64)(H,57,58)/t37-,38-,39-,40-/m0/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002491
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES Cc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H55N7O9/c1-28-17-19-29(20-18-28)21-22-38(53)47-23-11-10-16-34(41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-30-12-6-5-7-13-30)49-42(58)36(52-44(60)61-45(2,3)4)25-31-27-48-33-15-9-8-14-32(31)33/h5-9,12-15,17-22,27,34-37,48H,10-11,16,23-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b22-21-/t34-,35-,36-,37-/m0/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002525
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(F)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52FN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,48H,9-10,15,22-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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n/an/a 1.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002496
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H55N7O10/c1-45(2,3)62-44(60)52-36(25-30-27-48-33-15-9-8-14-32(30)33)42(58)49-34(16-10-11-23-47-38(53)22-19-28-17-20-31(61-4)21-18-28)41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,48H,10-11,16,23-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b22-19-/t34-,35-,36-,37-/m0/s1
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n/an/a 1.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin A receptor


(Cavia porcellus)		BDBM50002477
PNG
((S)-3-{(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1H...)
Show SMILES CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C34H44N6O8S/c1-34(2,3)48-33(47)40-26(17-21-19-36-23-13-9-8-12-22(21)23)31(45)37-24(14-15-49-4)30(44)39-27(18-28(41)42)32(46)38-25(29(35)43)16-20-10-6-5-7-11-20/h5-13,19,24-27,36H,14-18H2,1-4H3,(H2,35,43)(H,37,45)(H,38,46)(H,39,44)(H,40,47)(H,41,42)/t24-,25-,26-,27-/m0/s1
MMDB

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n/an/a 1.80E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig pancreas.

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002479
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H53N7O9/c1-44(2,3)60-43(59)51-35(25-30-27-47-32-19-11-10-18-31(30)32)41(57)48-33(20-12-13-23-46-37(52)22-21-28-14-6-4-7-15-28)40(56)50-36(26-38(53)54)42(58)49-34(39(45)55)24-29-16-8-5-9-17-29/h4-11,14-19,21-22,27,33-36,47H,12-13,20,23-26H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/b22-21-/t33-,34-,35-,36-/m0/s1
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n/an/a 1.80E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002474
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN(C)c1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C46H58N8O9/c1-46(2,3)63-45(62)53-37(26-31-28-49-34-16-10-9-15-33(31)34)43(60)50-35(17-11-12-24-48-39(55)23-20-29-18-21-32(22-19-29)54(4)5)42(59)52-38(27-40(56)57)44(61)51-36(41(47)58)25-30-13-7-6-8-14-30/h6-10,13-16,18-23,28,35-38,49H,11-12,17,24-27H2,1-5H3,(H2,47,58)(H,48,55)(H,50,60)(H,51,61)(H,52,59)(H,53,62)(H,56,57)/b23-20-/t35-,36-,37-,38-/m0/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002510
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cc2ccccc2[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52N8O9/c1-44(2,3)61-43(60)52-35(23-28-25-47-31-18-10-8-16-29(28)31)41(58)49-32(19-11-12-20-46-39(56)34-22-27-15-7-9-17-30(27)48-34)40(57)51-36(24-37(53)54)42(59)50-33(38(45)55)21-26-13-5-4-6-14-26/h4-10,13-18,22,25,32-33,35-36,47-48H,11-12,19-21,23-24H2,1-3H3,(H2,45,55)(H,46,56)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,53,54)/t32-,33-,35-,36-/m0/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002504
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1ccc2ccccc2c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O9/c1-46(2,3)62-45(61)53-37(25-32-27-49-34-18-10-9-17-33(32)34)43(59)50-35(19-11-12-22-48-41(57)31-21-20-29-15-7-8-16-30(29)24-31)42(58)52-38(26-39(54)55)44(60)51-36(40(47)56)23-28-13-5-4-6-14-28/h4-10,13-18,20-21,24,27,35-38,49H,11-12,19,22-23,25-26H2,1-3H3,(H2,47,56)(H,48,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t35-,36-,37-,38-/m0/s1
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n/an/a 2.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002508
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52ClN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,48H,9-10,15,22-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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n/an/a 2.90E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002502
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c(OC)c1
Show InChI InChI=1S/C46H57N7O11/c1-46(2,3)64-45(61)53-36(24-30-27-49-33-16-10-9-15-32(30)33)43(59)50-34(17-11-12-22-48-39(54)21-19-29-18-20-31(62-4)25-38(29)63-5)42(58)52-37(26-40(55)56)44(60)51-35(41(47)57)23-28-13-7-6-8-14-28/h6-10,13-16,18-21,25,27,34-37,49H,11-12,17,22-24,26H2,1-5H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b21-19-/t34-,35-,36-,37-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002486
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H54N8O10/c1-45(2,3)63-44(61)53-36(23-28-25-48-32-15-9-8-14-30(28)32)42(59)50-33(16-10-11-19-47-40(57)35-22-27-21-29(62-4)17-18-31(27)49-35)41(58)52-37(24-38(54)55)43(60)51-34(39(46)56)20-26-12-6-5-7-13-26/h5-9,12-15,17-18,21-22,25,33-34,36-37,48-49H,10-11,16,19-20,23-24H2,1-4H3,(H2,46,56)(H,47,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t33-,34-,36-,37-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002492
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1cccc(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(58)48-33(18-9-10-21-46-37(53)20-19-28-14-11-15-30(52)22-28)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-27-12-5-4-6-13-27/h4-8,11-17,22,26,33-36,47,52H,9-10,18-21,23-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002519
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)C=Cc1ccc(Cl)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H54ClN7O9/c1-45(2,3)62-44(61)52-35(25-30-27-49-33-15-9-8-14-32(30)33)42(59)50-34(16-10-11-23-48-38(54)22-19-28-17-20-31(46)21-18-28)41(58)51-36(26-39(55)56)43(60)53(4)37(40(47)57)24-29-12-6-5-7-13-29/h5-9,12-15,17-22,27,34-37,49H,10-11,16,23-26H2,1-4H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,58)(H,52,61)(H,55,56)/b22-19+/t34-,35-,36-,37-/m0/s1
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n/an/a 3.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002499
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CN([C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=O)CCc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C45H57N7O10/c1-45(2,3)62-44(61)51-35(25-30-27-48-33-15-9-8-14-32(30)33)42(59)49-34(16-10-11-23-47-38(54)22-19-28-17-20-31(53)21-18-28)41(58)50-36(26-39(55)56)43(60)52(4)37(40(46)57)24-29-12-6-5-7-13-29/h5-9,12-15,17-18,20-21,27,34-37,48,53H,10-11,16,19,22-26H2,1-4H3,(H2,46,57)(H,47,54)(H,49,59)(H,50,58)(H,51,61)(H,55,56)/t34-,35-,36-,37-/m0/s1
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n/an/a 3.60E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002480
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(\C=C/C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1OC
Show InChI InChI=1S/C46H57N7O11/c1-46(2,3)64-45(61)53-35(25-30-27-49-32-16-10-9-15-31(30)32)43(59)50-33(17-11-12-22-48-39(54)21-19-29-18-20-37(62-4)38(24-29)63-5)42(58)52-36(26-40(55)56)44(60)51-34(41(47)57)23-28-13-7-6-8-14-28/h6-10,13-16,18-21,24,27,33-36,49H,11-12,17,22-23,25-26H2,1-5H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b21-19-/t33-,34-,35-,36-/m0/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002494
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cccc2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H53N7O9/c1-46(2,3)62-45(61)53-37(25-30-27-49-34-21-10-9-19-32(30)34)43(59)50-35(22-11-12-23-48-41(57)33-20-13-17-29-16-7-8-18-31(29)33)42(58)52-38(26-39(54)55)44(60)51-36(40(47)56)24-28-14-5-4-6-15-28/h4-10,13-21,27,35-38,49H,11-12,22-26H2,1-3H3,(H2,47,56)(H,48,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t35-,36-,37-,38-/m0/s1
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n/an/a 4.30E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002478
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(O)c(O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O11/c1-44(2,3)62-43(61)51-33(23-28-25-47-30-14-8-7-13-29(28)30)41(59)48-31(15-9-10-20-46-37(54)19-17-27-16-18-35(52)36(53)22-27)40(58)50-34(24-38(55)56)42(60)49-32(39(45)57)21-26-11-5-4-6-12-26/h4-8,11-14,16,18,22,25,31-34,47,52-53H,9-10,15,17,19-21,23-24H2,1-3H3,(H2,45,57)(H,46,54)(H,48,59)(H,49,60)(H,50,58)(H,51,61)(H,55,56)/t31-,32-,33-,34-/m0/s1
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n/an/a 4.40E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002475
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(cc1)[N+]([O-])=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52N8O11/c1-44(2,3)63-43(60)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(58)48-33(15-9-10-22-46-37(53)21-18-27-16-19-30(20-17-27)52(61)62)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,47H,9-10,15,22-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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n/an/a 4.40E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50040523
PNG
((S)-3-{[(S)-2-[(S)-2-tert-Butoxycarbonylamino-3-(1...)
Show SMILES CN([C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)[C@H](CCCCNC(=O)Nc1ccccc1C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C
Show InChI InChI=1S/C44H56N8O9/c1-27-15-9-11-19-31(27)50-42(59)46-22-14-13-21-33(41(58)52(5)36(25-37(53)54)40(57)49-34(38(45)55)23-28-16-7-6-8-17-28)48-39(56)35(51-43(60)61-44(2,3)4)24-29-26-47-32-20-12-10-18-30(29)32/h6-12,15-20,26,33-36,47H,13-14,21-25H2,1-5H3,(H2,45,55)(H,48,56)(H,49,57)(H,51,60)(H,53,54)(H2,46,50,59)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002511
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)C=Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C46H54N8O9/c1-46(2,3)63-45(62)54-37(24-30-27-50-34-18-10-8-16-32(30)34)43(60)51-35(19-11-12-22-48-39(55)21-20-29-26-49-33-17-9-7-15-31(29)33)42(59)53-38(25-40(56)57)44(61)52-36(41(47)58)23-28-13-5-4-6-14-28/h4-10,13-18,20-21,26-27,35-38,49-50H,11-12,19,22-25H2,1-3H3,(H2,47,58)(H,48,55)(H,51,60)(H,52,61)(H,53,59)(H,54,62)(H,56,57)/b21-20+/t35-,36-,37-,38-/m0/s1
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n/an/a 4.70E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002493
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(OS(O)(=O)=O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(57)48-33(15-9-10-22-46-37(52)21-18-27-16-19-30(20-17-27)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,47H,9-10,15,18,21-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/t33-,34-,35-,36-/m0/s1
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n/an/a 4.80E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002526
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Cl)c(Cl)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H51Cl2N7O9/c1-44(2,3)62-43(61)53-35(23-28-25-49-32-14-8-7-13-29(28)32)41(59)50-33(15-9-10-20-48-37(54)19-17-27-16-18-30(45)31(46)21-27)40(58)52-36(24-38(55)56)42(60)51-34(39(47)57)22-26-11-5-4-6-12-26/h4-8,11-14,16-19,21,25,33-36,49H,9-10,15,20,22-24H2,1-3H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b19-17-/t33-,34-,35-,36-/m0/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002497
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Cl)cc1Cl)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H51Cl2N7O9/c1-44(2,3)62-43(61)53-35(22-28-25-49-32-14-8-7-13-30(28)32)41(59)50-33(15-9-10-20-48-37(54)19-17-27-16-18-29(45)23-31(27)46)40(58)52-36(24-38(55)56)42(60)51-34(39(47)57)21-26-11-5-4-6-12-26/h4-8,11-14,16-19,23,25,33-36,49H,9-10,15,20-22,24H2,1-3H3,(H2,47,57)(H,48,54)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,55,56)/b19-17-/t33-,34-,35-,36-/m0/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002509
PNG
(3-{6-[3-(4-Bromo-phenyl)-acryloylamino]-2-[2-tert-...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(Br)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H52BrN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,48H,9-10,15,22-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/b21-18-/t33-,34-,35-,36-/m0/s1
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n/an/a 5.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002517
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H51ClN8O9/c1-44(2,3)62-43(61)53-35(22-27-24-48-31-14-8-7-13-29(27)31)41(59)50-32(15-9-10-18-47-39(57)34-21-26-20-28(45)16-17-30(26)49-34)40(58)52-36(23-37(54)55)42(60)51-33(38(46)56)19-25-11-5-4-6-12-25/h4-8,11-14,16-17,20-21,24,32-33,35-36,48-49H,9-10,15,18-19,22-23H2,1-3H3,(H2,46,56)(H,47,57)(H,50,59)(H,51,60)(H,52,58)(H,53,61)(H,54,55)/t32-,33-,35-,36-/m0/s1
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n/an/a 5.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002503
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)\C=C/c1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H52F3N7O9/c1-44(2,3)64-43(63)55-35(24-29-26-51-32-14-8-7-13-31(29)32)41(61)52-33(15-9-10-22-50-37(56)21-18-27-16-19-30(20-17-27)45(46,47)48)40(60)54-36(25-38(57)58)42(62)53-34(39(49)59)23-28-11-5-4-6-12-28/h4-8,11-14,16-21,26,33-36,51H,9-10,15,22-25H2,1-3H3,(H2,49,59)(H,50,56)(H,52,61)(H,53,62)(H,54,60)(H,55,63)(H,57,58)/b21-18-/t33-,34-,35-,36-/m0/s1
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n/an/a 5.30E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002522
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O9/c1-44(2,3)60-43(59)51-35(25-30-27-47-32-19-11-10-18-31(30)32)41(57)48-33(20-12-13-23-46-37(52)22-21-28-14-6-4-7-15-28)40(56)50-36(26-38(53)54)42(58)49-34(39(45)55)24-29-16-8-5-9-17-29/h4-11,14-19,27,33-36,47H,12-13,20-26H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/t33-,34-,35-,36-/m0/s1
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n/an/a 5.90E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002520
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O10/c1-44(2,3)61-43(60)51-35(24-29-26-47-32-14-8-7-13-31(29)32)41(58)48-33(15-9-10-22-46-37(53)21-18-27-16-19-30(52)20-17-27)40(57)50-36(25-38(54)55)42(59)49-34(39(45)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,47,52H,9-10,15,18,21-25H2,1-3H3,(H2,45,56)(H,46,53)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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n/an/a 6.10E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002476
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(Cl)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H54ClN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,48H,9-10,15,18,21-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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n/an/a 7.00E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002527
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(F)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H54FN7O9/c1-44(2,3)61-43(60)52-35(24-29-26-48-32-14-8-7-13-31(29)32)41(58)49-33(15-9-10-22-47-37(53)21-18-27-16-19-30(45)20-17-27)40(57)51-36(25-38(54)55)42(59)50-34(39(46)56)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,48H,9-10,15,18,21-25H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t33-,34-,35-,36-/m0/s1
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n/an/a 9.90E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002512
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCC1CCCCC1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H61N7O9/c1-44(2,3)60-43(59)51-35(25-30-27-47-32-19-11-10-18-31(30)32)41(57)48-33(20-12-13-23-46-37(52)22-21-28-14-6-4-7-15-28)40(56)50-36(26-38(53)54)42(58)49-34(39(45)55)24-29-16-8-5-9-17-29/h5,8-11,16-19,27-28,33-36,47H,4,6-7,12-15,20-26H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)/t33-,34-,35-,36-/m0/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002505
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES Cc1ccc(CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H57N7O9/c1-28-17-19-29(20-18-28)21-22-38(53)47-23-11-10-16-34(41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-30-12-6-5-7-13-30)49-42(58)36(52-44(60)61-45(2,3)4)25-31-27-48-33-15-9-8-14-32(31)33/h5-9,12-15,17-20,27,34-37,48H,10-11,16,21-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t34-,35-,36-,37-/m0/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002507
PNG
(3-[2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCCc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H57N7O9/c1-45(2,3)61-44(60)52-36(26-31-28-48-33-21-11-10-20-32(31)33)42(58)49-34(22-12-13-24-47-38(53)23-14-19-29-15-6-4-7-16-29)41(57)51-37(27-39(54)55)43(59)50-35(40(46)56)25-30-17-8-5-9-18-30/h4-11,15-18,20-21,28,34-37,48H,12-14,19,22-27H2,1-3H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t34-,35-,36-,37-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002495
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES COc1ccc(CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C45H57N7O10/c1-45(2,3)62-44(60)52-36(25-30-27-48-33-15-9-8-14-32(30)33)42(58)49-34(16-10-11-23-47-38(53)22-19-28-17-20-31(61-4)21-18-28)41(57)51-37(26-39(54)55)43(59)50-35(40(46)56)24-29-12-6-5-7-13-29/h5-9,12-15,17-18,20-21,27,34-37,48H,10-11,16,19,22-26H2,1-4H3,(H2,46,56)(H,47,53)(H,49,58)(H,50,59)(H,51,57)(H,52,60)(H,54,55)/t34-,35-,36-,37-/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002489
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1cccc(OS(O)(=O)=O)c1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C44H55N7O13S/c1-44(2,3)63-43(59)51-35(24-29-26-47-32-17-8-7-16-31(29)32)41(57)48-33(18-9-10-21-46-37(52)20-19-28-14-11-15-30(22-28)64-65(60,61)62)40(56)50-36(25-38(53)54)42(58)49-34(39(45)55)23-27-12-5-4-6-13-27/h4-8,11-17,22,26,33-36,47H,9-10,18-21,23-25H2,1-3H3,(H2,45,55)(H,46,52)(H,48,57)(H,49,58)(H,50,56)(H,51,59)(H,53,54)(H,60,61,62)/t33-,34-,35-,36-/m0/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(Homo sapiens (Human))		BDBM50002518
PNG
(3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)CCc1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C45H54F3N7O9/c1-44(2,3)64-43(63)55-35(24-29-26-51-32-14-8-7-13-31(29)32)41(61)52-33(15-9-10-22-50-37(56)21-18-27-16-19-30(20-17-27)45(46,47)48)40(60)54-36(25-38(57)58)42(62)53-34(39(49)59)23-28-11-5-4-6-12-28/h4-8,11-14,16-17,19-20,26,33-36,51H,9-10,15,18,21-25H2,1-3H3,(H2,49,59)(H,50,56)(H,52,61)(H,53,62)(H,54,60)(H,55,63)(H,57,58)/t33-,34-,35-,36-/m0/s1
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n/an/a 1.90E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]BH-CCK-8 in guinea pig cortex

J Med Chem 35: 2007-14 (1992)


Article DOI: 10.1021/jm00089a010
BindingDB Entry DOI: 10.7270/Q21J9BDC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%