Affinity Data by PubMed id=1404238

PubMed code 1404238

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine A1 receptor (GUINEA PIG)	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor using N6-[3H]-cyclohexyladenosine in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM50003021 (7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards Adenosine A1 receptor using N6-[3H]-cyclohexyladenosine in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM50003024 ((8-(dicyclopropylmethyl)-1,3-dipropylxanthine)8-Di...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor using N6-[3H]-cyclohexyladenosine in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM50003023 (7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towardsAdenosine A1 receptor using N6-[3H]-cyclohexyladenosine in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor using N6-[3H]-cyclohexyladenosine in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM50003018 (8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-pur...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards adenosine A1 receptor using N6-[3H]-cyclohexyladenosine in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM50003022 (7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards Adenosine A1 receptor using N6-[3H]-cyclohexyladenosine in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM50003022 (7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards Adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM50003021 (7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards Adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM50003023 (7-Ethyl-2-(hexahydro-2,5-methano-pentalen-3a-yl)-4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity towards Adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM50003019 (8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity for adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM50003024 ((8-(dicyclopropylmethyl)-1,3-dipropylxanthine)8-Di...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity for adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine \| 8-cyclopentyl...) Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity for adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM50003018 (8-(3-Oxo-cyclopentyl)-1,3-dipropyl-3,7-dihydro-pur...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity for adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in guinea pig forebrain membranes				J Med Chem 35: 3578-81 (1992) Article DOI: 10.1021/jm00097a016 BindingDB Entry DOI: 10.7270/Q28K781C
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%