Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lanosterol synthase (Rattus norvegicus) | BDBM50003025![]() (1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003026![]() (1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003032![]() ((4aS,5S,6S,8aS)-2-Dodecyl-5,8a-dimethyl-decahydro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003027![]() ((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003030![]() ((2S,4aS,8aR)-1,1,4a-Trimethyl-decahydro-naphthalen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003028![]() (2-(Dodecane-1-sulfinyl)-5,8a-dimethyl-decahydro-is...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003031![]() (1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003029![]() (2-(Dodecane-1-sulfonyl)-5,8a-dimethyl-decahydro-is...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) Article DOI: 10.1021/jm00097a017 BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair |