Affinity Data by PubMed id=1404239

PubMed code 1404239

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lanosterol synthase (Rattus norvegicus)	BDBM50003025 (1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50003026 (1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50003032 ((4aS,5S,6S,8aS)-2-Dodecyl-5,8a-dimethyl-decahydro-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50003027 ((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50003030 ((2S,4aS,8aR)-1,1,4a-Trimethyl-decahydro-naphthalen...) Show SMILES CC1(C)[C@@H](O)CC[C@]2(C)CCCC[C@@H]12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50003028 (2-(Dodecane-1-sulfinyl)-5,8a-dimethyl-decahydro-is...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50003031 (1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol synthase (Rattus norvegicus)	BDBM50003029 (2-(Dodecane-1-sulfonyl)-5,8a-dimethyl-decahydro-is...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver				Citation and Details
Marion Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%