Affinity Data by PubMed id=1433181

PubMed code 1433181

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003110 (CHEMBL543891 \| N-[3-(3,5-Di-tert-butyl-4-hydroxy-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003126 (4-(5-Amino-[1,2,4]thiadiazol-3-yl)-2,6-di-tert-but...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003125 (CHEMBL542464 \| N-[3-(3,5-Di-tert-butyl-4-hydroxy-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003124 (2,6-Di-tert-butyl-4-(3-chloromethyl-[1,2,4]oxadiaz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against 5-Lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003123 (1-[3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,2,4]t...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003112 (CHEMBL123210 \| N-[5-(3,5-Di-tert-butyl-4-hydroxy-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against 5-Lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003116 (CHEMBL331793 \| N-[3-(3,5-Di-tert-butyl-4-hydroxy-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50075539 (3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,2,4]thia...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against 5-Lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003111 (2,6-Di-tert-butyl-4-(5-methyl-[1,2,4]oxadiazol-3-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003119 (4-(5-Amino-[1,2,4]oxadiazol-3-yl)-2,6-di-tert-buty...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003121 (3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-dihydro-fur...) Show SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C1CCOC1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003122 (4-(5-Aminomethyl-[1,2,4]thiadiazol-3-yl)-2,6-di-te...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003127 (CHEMBL122193 \| CHEMBL1626562 \| CHEMBL16659 \| choli...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory activity against 5-Lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003114 (2,6-Di-tert-butyl-4-(3-methyl-[1,2,4]oxadiazol-5-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003117 (3-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-4H-[1,2,4]o...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003113 (4-(3-Amino-[1,2,4]oxadiazol-5-yl)-2,6-di-tert-buty...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003109 (2,6-Di-tert-butyl-4-(3-dimethylaminomethyl-[1,2,4]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50003118 (2,6-Di-tert-butyl-4-(5-dimethylaminomethyl-[1,2,4]...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50012896 (CHEMBL876 \| CL-583.NA SALT \| MECLOFENAMATE SODIUM ...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2C([O-])=O)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Evaluated in vitro for its inhibitory activity against 5-lipoxygenase				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%