Affinity Data by PubMed id=1433182

PubMed code 1433182

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003134 (3-Octyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CCCCCCCC[C@@]1(CCC(=O)NC1=O)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003135 ((R)-3-Ethyl-5-octyl-4,5-dihydro-3H-[3,4']bipyridin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003135 ((R)-3-Ethyl-5-octyl-4,5-dihydro-3H-[3,4']bipyridin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50406684 (CHEMBL2111801) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003131 (3-Ethyl-5-nonyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003129 (5-Butyl-3-ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003133 (3-Ethyl-5-methyl-4,5-dihydro-3H-[3,4']bipyridinyl-...) Show SMILES CC[C@@]1(C[C@H](C)C(=O)NC1=O)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003137 (3,5-Dioctyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-d...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003130 (3-Ethyl-4,5-dihydro-3H-[3,4']bipyridinyl-2,6-dione...) Show SMILES CC[C@@]1(CCC(=O)NC1=O)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003136 (3-Ethyl-5-methyl-4,5-dihydro-3H-[3,4']bipyridinyl-...) Show SMILES CC[C@@]1(C[C@@H](C)C(=O)NC1=O)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (CYP19) (Homo sapiens (human))	BDBM50003132 (3-Ethyl-5,5-dimethyl-4,5-dihydro-3H-[3,4']bipyridi...) Show SMILES CC[C@@]1(CC(C)(C)C(=O)NC1=O)c1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of Cytochrome P450 19A1				Citation and Details
Institute of Cancer Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%