Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003319![]() (3-(2-{5-Guanidino-2-[(2-mercapto-benzoyl)-methyl-a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003322![]() (3-(2-{2-[(2-Acetylamino-3-mercapto-propionyl)-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 175 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003317![]() (CHEMBL339832 | [18-(3-Guanidino-propyl)-2,8,11,14,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003321![]() (3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003325![]() (3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003315![]() (CHEMBL421247 | [5-Benzyl-17-(3-guanidino-propyl)-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003314![]() (CHEMBL129782 | [18-(3-Guanidino-propyl)-2,5,11,14,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003319![]() (3-(2-{5-Guanidino-2-[(2-mercapto-benzoyl)-methyl-a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003316![]() (3-{2-[5-Guanidino-2-(2-mercapto-benzoylamino)-pent...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003322![]() (3-(2-{2-[(2-Acetylamino-3-mercapto-propionyl)-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to Fibrinogen Receptor from human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003318![]() (3-(2-{2-[(2-Acetylamino-3-mercapto-propionyl)-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to fibrinogen receptor of human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003325![]() (3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003313![]() (3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003317![]() (CHEMBL339832 | [18-(3-Guanidino-propyl)-2,8,11,14,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to fibrinogen receptor of human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003323![]() (3-[2-(2-{2-[2-(2-Amino-acetylamino)-3-mercapto-3-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to GPIIb/IIIa from human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003315![]() (CHEMBL421247 | [5-Benzyl-17-(3-guanidino-propyl)-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of [3H]-Mba-(N-Me)Arg-Gly-Asp-Man binding to fibrinogen receptor of human platelets reconstituted in liposomes | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003321![]() (3-{2-[2-(2-Acetylamino-3-mercapto-propionylamino)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003314![]() (CHEMBL129782 | [18-(3-Guanidino-propyl)-2,5,11,14,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003324![]() (CHEMBL384237 | [3,21-Dibenzyl-24-carboxymethyl-12,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50003320![]() (CHEMBL450009 | [15-(3-Guanidino-propyl)-2,8,11,14,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasma | J Med Chem 35: 3962-9 (1992) Article DOI: 10.1021/jm00099a026 BindingDB Entry DOI: 10.7270/Q2028QG9 | |||||||||||
More data for this Ligand-Target Pair |