Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human)) | BDBM50002472![]() (5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 4078-85 (1992) Article DOI: 10.1021/jm00100a013 BindingDB Entry DOI: 10.7270/Q26M35S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human)) | BDBM50003467![]() (5-Amino-2-{4-[(2-amino-4-oxo-5-trifluoromethyl-3,4...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 4078-85 (1992) Article DOI: 10.1021/jm00100a013 BindingDB Entry DOI: 10.7270/Q26M35S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human)) | BDBM50003471![]() (5-Amino-2-{4-[(2-amino-4-oxo-5-trifluoromethyl-3,4...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 4078-85 (1992) Article DOI: 10.1021/jm00100a013 BindingDB Entry DOI: 10.7270/Q26M35S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human)) | BDBM50003470![]() (5-Amino-2-{4-[(5-fluoro-2-methyl-4-oxo-3,4-dihydro...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 4078-85 (1992) Article DOI: 10.1021/jm00100a013 BindingDB Entry DOI: 10.7270/Q26M35S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human)) | BDBM50003468![]() (5-Amino-2-{4-[(2-amino-5-chloro-4-oxo-3,4-dihydro-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 4078-85 (1992) Article DOI: 10.1021/jm00100a013 BindingDB Entry DOI: 10.7270/Q26M35S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human)) | BDBM50003469![]() (5-Amino-2-{4-[(2-amino-5-fluoro-4-oxo-3,4-dihydro-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 4078-85 (1992) Article DOI: 10.1021/jm00100a013 BindingDB Entry DOI: 10.7270/Q26M35S6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Folylpoly-gamma-glutamate synthetase (Homo sapiens (Human)) | BDBM50002473![]() (5-Amino-2-{4-[(2-amino-4-oxo-3,4-dihydro-pteridin-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibitory activity of the compound against hog liver Folyl polyglutamate synthetase (FPGS) | J Med Chem 35: 4078-85 (1992) Article DOI: 10.1021/jm00100a013 BindingDB Entry DOI: 10.7270/Q26M35S6 | |||||||||||
More data for this Ligand-Target Pair |