Affinity Data by PubMed id=1469704

PubMed code 1469704

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus (rat))	BDBM50004169 ((2S,3S)-3-(4-Chloro-phenyl)-8-methyl-2-vinyl-8-aza...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Education and Research Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranes				J Med Chem 35: 4764-6 (1993) Article DOI: 10.1021/jm00103a015 BindingDB Entry DOI: 10.7270/Q2QR4XQT
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus (rat))	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Education and Research Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranes				J Med Chem 35: 4764-6 (1993) Article DOI: 10.1021/jm00103a015 BindingDB Entry DOI: 10.7270/Q2QR4XQT
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus (rat))	BDBM50004170 (Benzoic acid 2-(2-chloro-vinyl)-8-methyl-8-aza-bic...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Education and Research Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranes				J Med Chem 35: 4764-6 (1993) Article DOI: 10.1021/jm00103a015 BindingDB Entry DOI: 10.7270/Q2QR4XQT
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus (rat))	BDBM22418 (Cocaine \| Cocaine (-) \| methyl (1R,2R,3S,5S)-3-(be...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Education and Research Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranes				J Med Chem 35: 4764-6 (1993) Article DOI: 10.1021/jm00103a015 BindingDB Entry DOI: 10.7270/Q2QR4XQT
					More data for this Ligand-Target Pair
Monoamine transporters; Norepininephrine & dopamine (Rattus norvegicus (rat))	BDBM50004168 (Benzoic acid 8-methyl-2-vinyl-8-aza-bicyclo[3.2.1]...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Education and Research Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]mazindol binding from rat striatal membranes				J Med Chem 35: 4764-6 (1993) Article DOI: 10.1021/jm00103a015 BindingDB Entry DOI: 10.7270/Q2QR4XQT
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%