Compile Data Set for Download or QSAR
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Found 6 Enz. Inhib. hit(s) with all data for entry = 50014195
TargetTyrosinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50139369(2-Hydroxy-4-isopropyl-benzaldehyde | CHEMBL353354)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50139368(2-Hydroxy-4-methoxy-benzaldehyde | 2-hydroxy-4-met...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50139366(4-Isopropyl-benzaldehyde | 4-isopropylbenzaldehyde...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50139370(4-Methoxy-benzaldehyde | 4-methoxybenzaldehyde | C...)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM60953(BDBM50139371 | benzaldehyde)
Affinity DataIC50:  8.20E+5nMAssay Description:Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50139367(2-hydroxybenzaldehyde | CHEMBL108925 | Salicylalde...)
Affinity DataIC50:  3.30E+6nMAssay Description:Inhibitory activity of the compound was evaluated against the oxidation of L-3,4-dihydroxyphenylalanine (L-DOPA) catalyzed by mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed