Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-citrate synthase (Rattus norvegicus) | BDBM50368516![]() (CHEMBL1627232) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase | J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-citrate synthase (Rattus norvegicus) | BDBM50004265![]() (2-(3-Hydroxy-2-oxo-azetidin-3-ylmethyl)-succinic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >9.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase | J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-citrate synthase (Rattus norvegicus) | BDBM50368516![]() (CHEMBL1627232) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase | J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-citrate synthase (Rattus norvegicus) | BDBM50004264![]() (2-(3-Hydroxy-2-oxo-azetidin-3-ylmethyl)-succinic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase | J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC | |||||||||||
More data for this Ligand-Target Pair |