Affinity Data by PubMed id=1479587

PubMed code 1479587

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-citrate synthase (Rattus norvegicus)	BDBM50368516 (CHEMBL1627232) Show SMILES CS(N)(=O)=C[C@@](O)(CC(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase				J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50004265 (2-(3-Hydroxy-2-oxo-azetidin-3-ylmethyl)-succinic a...) Show SMILES OC(=O)C[C@H](C[C@]1(O)CNC1=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>9.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase				J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50368516 (CHEMBL1627232) Show SMILES CS(N)(=O)=C[C@@](O)(CC(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase				J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50004264 (2-(3-Hydroxy-2-oxo-azetidin-3-ylmethyl)-succinic a...) Show SMILES OC(=O)C[C@H](C[C@@]1(O)CNC1=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Reversible binding Ki was measured by the inhibition of the carbon-carbon bond cleavage activity against rat ATP-Citrate Lyase				J Med Chem 35: 4875-84 (1992) Article DOI: 10.1021/jm00104a014 BindingDB Entry DOI: 10.7270/Q2G73FBC
SmithKline Beecham Pharmaceuticals Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%