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PubMed code 1479590

Compile data set for download or QSAR
Found 34 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM21395
PNG
(3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1
Show InChI InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)
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50n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50454090
PNG
(CHEMBL19491)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2)CC1
Show InChI InChI=1S/C20H22FNO/c21-19-8-6-17(7-9-19)20(23)18-11-14-22(15-12-18)13-10-16-4-2-1-3-5-16/h1-9,18H,10-15H2
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145n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368517
PNG
(CHEMBL1202023)
Show SMILES Fc1ccc(CC2CCN(CCn3c(=O)[nH]c4ccccc4c3=O)CC2)cc1
Show InChI InChI=1S/C22H24FN3O2/c23-18-7-5-16(6-8-18)15-17-9-11-25(12-10-17)13-14-26-21(27)19-3-1-2-4-20(19)24-22(26)28/h1-8,17H,9-15H2,(H,24,28)
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200n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368521
PNG
(CHEMBL1202028)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCNC(=O)Nc2ccccc2)CC1
Show InChI InChI=1S/C21H24FN3O2/c22-18-8-6-16(7-9-18)20(26)17-10-13-25(14-11-17)15-12-23-21(27)24-19-4-2-1-3-5-19/h1-9,17H,10-15H2,(H2,23,24,27)
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200n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004320
PNG
(4-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-1-(4-fluor...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C22H23F2NO2/c23-19-7-3-16(4-8-19)21(26)2-1-13-25-14-11-18(12-15-25)22(27)17-5-9-20(24)10-6-17/h3-10,18H,1-2,11-15H2
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345n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368532
PNG
(CHEMBL1203375)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCC(=O)c2ccccc2)CC1
Show InChI InChI=1S/C22H24FNO2/c23-20-10-8-18(9-11-20)22(26)19-12-15-24(16-13-19)14-4-7-21(25)17-5-2-1-3-6-17/h1-3,5-6,8-11,19H,4,7,12-16H2
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350n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368525
PNG
(CHEMBL1202029)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCCc2ccccc2)CC1
Show InChI InChI=1S/C23H28FNO/c24-22-12-10-20(11-13-22)23(26)21-14-17-25(18-15-21)16-6-2-5-9-19-7-3-1-4-8-19/h1,3-4,7-8,10-13,21H,2,5-6,9,14-18H2
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420n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004337
PNG
((4-Fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-...)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCCc2ccccc2)CC1
Show InChI InChI=1S/C22H26FNO/c23-21-11-9-19(10-12-21)22(25)20-13-16-24(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20H,4-5,8,13-17H2
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620n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368518
PNG
(CHEMBL1744162)
Show SMILES O=C(C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1)c1ccccc1
Show InChI InChI=1S/C22H23N3O3/c26-20(16-6-2-1-3-7-16)17-10-12-24(13-11-17)14-15-25-21(27)18-8-4-5-9-19(18)23-22(25)28/h1-9,17H,10-15H2,(H,23,28)
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760n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368533
PNG
(CHEMBL1202030)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C21H24FNO/c22-20-10-8-18(9-11-20)21(24)19-12-15-23(16-13-19)14-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11,19H,4,7,12-16H2
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940n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368530
PNG
(CHEMBL1744160)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H25N3O2/c26-21-19-8-4-5-9-20(19)23-22(27)25(21)15-14-24-12-10-18(11-13-24)16-17-6-2-1-3-7-17/h1-9,18H,10-16H2,(H,23,27)
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970n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004316
PNG
((4-Fluoro-phenyl)-piperidin-4-yl-methanone | (4-fl...)
Show SMILES Fc1ccc(cc1)C(=O)C1CCNCC1
Show InChI InChI=1S/C12H14FNO/c13-11-3-1-9(2-4-11)12(15)10-5-7-14-8-6-10/h1-4,10,14H,5-8H2
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1.10E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368535
PNG
(CHEMBL1202027)
Show SMILES CN(CCCc1ccccc1)CCn1c(=O)[nH]c2ccccc2c1=O
Show InChI InChI=1S/C20H23N3O2/c1-22(13-7-10-16-8-3-2-4-9-16)14-15-23-19(24)17-11-5-6-12-18(17)21-20(23)25/h2-6,8-9,11-12H,7,10,13-15H2,1H3,(H,21,25)
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1.39E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004330
PNG
((4-Fluoro-phenyl)-(1-methyl-piperidin-4-yl)-methan...)
Show SMILES CN1CCC(CC1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C13H16FNO/c1-15-8-6-11(7-9-15)13(16)10-2-4-12(14)5-3-10/h2-5,11H,6-9H2,1H3
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1.51E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368526
PNG
(CHEMBL1202026)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCNC(=O)c2ccccc2)CC1
Show InChI InChI=1S/C21H23FN2O2/c22-19-8-6-16(7-9-19)20(25)17-10-13-24(14-11-17)15-12-23-21(26)18-4-2-1-3-5-18/h1-9,17H,10-15H2,(H,23,26)
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1.61E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368537
PNG
(CHEMBL1202025)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C19H20FNO/c20-18-8-6-16(7-9-18)19(22)17-10-12-21(13-11-17)14-15-4-2-1-3-5-15/h1-9,17H,10-14H2
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3.00E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004307
PNG
((1-Ethyl-piperidin-4-yl)-(4-fluoro-phenyl)-methano...)
Show SMILES CCN1CCC(CC1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C14H18FNO/c1-2-16-9-7-12(8-10-16)14(17)11-3-5-13(15)6-4-11/h3-6,12H,2,7-10H2,1H3
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3.16E+3n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368522
PNG
(CHEMBL1744164)
Show SMILES CCN1CCC(CC1)C(O)c1ccc(F)cc1
Show InChI InChI=1S/C14H20FNO/c1-2-16-9-7-12(8-10-16)14(17)11-3-5-13(15)6-4-11/h3-6,12,14,17H,2,7-10H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368527
PNG
(CHEMBL1202024)
Show SMILES OC(C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1)c1ccccc1
Show InChI InChI=1S/C22H25N3O3/c26-20(16-6-2-1-3-7-16)17-10-12-24(13-11-17)14-15-25-21(27)18-8-4-5-9-19(18)23-22(25)28/h1-9,17,20,26H,10-15H2,(H,23,28)
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004323
PNG
(CHEMBL113624 | Phenyl-piperazin-1-yl-methanone)
Show SMILES O=C(N1CCNCC1)c1ccccc1
Show InChI InChI=1S/C11H14N2O/c14-11(10-4-2-1-3-5-10)13-8-6-12-7-9-13/h1-5,12H,6-9H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368520
PNG
(CHEMBL1744161)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCNCCCc1ccccc1
Show InChI InChI=1S/C19H21N3O2/c23-18-16-10-4-5-11-17(16)21-19(24)22(18)14-13-20-12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,20H,6,9,12-14H2,(H,21,24)
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004308
PNG
(1-Benzoylpiperazine | 1-Benzyl-piperazine | 1-Benz...)
Show SMILES C(N1CCNCC1)c1ccccc1
Show InChI InChI=1S/C11H16N2/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13/h1-5,12H,6-10H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368524
PNG
(CHEMBL1203378)
Show SMILES CN1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1
Show InChI InChI=1S/C15H20N4O2/c1-17-6-8-18(9-7-17)10-11-19-14(20)12-4-2-3-5-13(12)16-15(19)21/h2-5H,6-11H2,1H3,(H,16,21)
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368519
PNG
(CHEMBL1203376)
Show SMILES NCCn1c(=O)[nH]c2ccccc2c1=O
Show InChI InChI=1S/C10H11N3O2/c11-5-6-13-9(14)7-3-1-2-4-8(7)12-10(13)15/h1-4H,5-6,11H2,(H,12,15)
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004302
PNG
(3-(2-Dimethylamino-ethyl)-1H-quinazoline-2,4-dione...)
Show SMILES CN(C)CCn1c(=O)[nH]c2ccccc2c1=O
Show InChI InChI=1S/C12H15N3O2/c1-14(2)7-8-15-11(16)9-5-3-4-6-10(9)13-12(15)17/h3-6H,7-8H2,1-2H3,(H,13,17)
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368531
PNG
(CHEMBL1744163)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCNCCCCc1ccccc1
Show InChI InChI=1S/C20H23N3O2/c24-19-17-11-4-5-12-18(17)22-20(25)23(19)15-14-21-13-7-6-10-16-8-2-1-3-9-16/h1-5,8-9,11-12,21H,6-7,10,13-15H2,(H,22,25)
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004303
PNG
(CHEMBL344115 | Phenyl-piperidin-4-yl-methanone)
Show SMILES O=C(C1CCNCC1)c1ccccc1
Show InChI InChI=1S/C12H15NO/c14-12(10-4-2-1-3-5-10)11-6-8-13-9-7-11/h1-5,11,13H,6-9H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004317
PNG
(4-Benzyl-piperidine | CHEMBL144129)
Show SMILES C(C1CCNCC1)c1ccccc1
Show InChI InChI=1S/C12H17N/c1-2-4-11(5-3-1)10-12-6-8-13-9-7-12/h1-5,12-13H,6-10H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368534
PNG
(CHEMBL1203377)
Show SMILES CN1CCN(Cc2ccc(F)cc2)CC1
Show InChI InChI=1S/C12H17FN2/c1-14-6-8-15(9-7-14)10-11-2-4-12(13)5-3-11/h2-5H,6-10H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368523
PNG
(CHEMBL1203374)
Show SMILES CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C13H19N/c1-14-9-7-13(8-10-14)11-12-5-3-2-4-6-12/h2-6,13H,7-11H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004333
PNG
((4-Fluoro-phenyl)-(4-methyl-piperazin-1-yl)-methan...)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C12H15FN2O/c1-14-6-8-15(9-7-14)12(16)10-2-4-11(13)5-3-10/h2-5H,6-9H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50004309
PNG
((4-Methyl-piperazin-1-yl)-phenyl-methanone | CHEMB...)
Show SMILES CN1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C12H16N2O/c1-13-7-9-14(10-8-13)12(15)11-5-3-2-4-6-11/h2-6H,7-10H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM50368528
PNG
(CHEMBL1203379)
Show SMILES O=c1[nH]c2ccccc2c(=O)n1CCN1CCCCC1
Show InChI InChI=1S/C15H19N3O2/c19-14-12-6-2-3-7-13(12)16-15(20)18(14)11-10-17-8-4-1-5-9-17/h2-3,6-7H,1,4-5,8-11H2,(H,16,20)
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C)


(Rattus norvegicus (Rat))
BDBM15788
PNG
(4-[(4-fluorophenyl)methyl]piperidine | CHEMBL12043...)
Show SMILES Fc1ccc(CC2CCNCC2)cc1
Show InChI InChI=1S/C12H16FN/c13-12-3-1-10(2-4-12)9-11-5-7-14-8-6-11/h1-4,11,14H,5-9H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%