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PubMed code 1495016

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50229848
PNG
(CHEMBL1202910)
Show SMILES Cl.Brc1ccccc1[C@H]1CC[C@H]2CCCCN12
Show InChI InChI=1S/C14H18BrN.ClH/c15-13-7-2-1-6-12(13)14-9-8-11-5-3-4-10-16(11)14;/h1-2,6-7,11,14H,3-5,8-10H2;1H/t11-,14-;/m1./s1
UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem

Similars

Article
PubMed
1.12E+3n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H] clonidine as radioligand in rat brain cortex


J Med Chem 35: 2855-63 (1992)


Article DOI: 10.1021/jm00093a019
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50229848
PNG
(CHEMBL1202910)
Show SMILES Cl.Brc1ccccc1[C@H]1CC[C@H]2CCCCN12
Show InChI InChI=1S/C14H18BrN.ClH/c15-13-7-2-1-6-12(13)14-9-8-11-5-3-4-10-16(11)14;/h1-2,6-7,11,14H,3-5,8-10H2;1H/t11-,14-;/m1./s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.20E+3n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H]- clonidine as radioligand in rat brain cortex.


J Med Chem 35: 2855-63 (1992)


Article DOI: 10.1021/jm00093a019
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50229848
PNG
(CHEMBL1202910)
Show SMILES Cl.Brc1ccccc1[C@H]1CC[C@H]2CCCCN12
Show InChI InChI=1S/C14H18BrN.ClH/c15-13-7-2-1-6-12(13)14-9-8-11-5-3-4-10-16(11)14;/h1-2,6-7,11,14H,3-5,8-10H2;1H/t11-,14-;/m1./s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.84E+3n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory constant was measured on alpha-2 adrenergic receptor /uptake using [3H]- clonidine as radioligand in rat brain cortex.


J Med Chem 35: 2855-63 (1992)


Article DOI: 10.1021/jm00093a019
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%