Compile Data Set for Download or QSAR
maximum 50k data
Found 31 Enz. Inhib. hit(s) with all data for entry = 50014381
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141817(CHEMBL171509 | [1-(2-{4-[4-(4-tert-Butyl-phenylami...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141829((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141822((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50:  54nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141819((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50:  63nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141812(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-2-fluoro-phe...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141823(2-[(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-...)
Affinity DataIC50:  71nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141813(1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-meth...)
Affinity DataIC50:  71nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)
Affinity DataIC50:  83nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)
Affinity DataIC50:  88nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141810((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)
Affinity DataIC50:  100nMAssay Description:Inhibition of c-Kit autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141832((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141821((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50:  190nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141814(CHEMBL276125 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141816(1-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-meth...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141824((4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(2-morpholin...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141811(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-3-fluoro-phe...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141831((4-tert-Butyl-phenyl)-{4-[6-methoxy-7-(3-piperidin...)
Affinity DataIC50:  350nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141827(4-[4-(4-tert-Butyl-phenoxy)-phenoxy]-6,7-dimethoxy...)
Affinity DataIC50:  440nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)
Affinity DataIC50:  480nMAssay Description:Inhibition of PDGF-receptor autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141826(CHEMBL354830 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)
Affinity DataIC50:  780nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141830(4-[4-(4-tert-Butyl-benzyl)-phenoxy]-6,7-dimethoxy-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141828((4-tert-Butyl-cyclohexyl)-[4-(6,7-dimethoxy-quinol...)
Affinity DataIC50:  3.40E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141808(Biphenyl-4-yl-[4-(6,7-dimethoxy-quinolin-4-yloxy)-...)
Affinity DataIC50:  4.60E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141825(CHEMBL172746 | [4-(6,7-Dimethoxy-quinolin-4-yloxy)...)
Affinity DataIC50:  8.90E+3nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGF-receptor autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IGF-receptor 1 autophosphorylation in intact cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141809(2-(2-{4-[4-(4-tert-Butyl-phenylamino)-phenoxy]-6-m...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-Met autophosphorylation of in intact cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141818(Biphenyl-3-yl-[4-(6,7-dimethoxy-quinolin-4-yloxy)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141815((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM50141820((4-tert-Butyl-phenyl)-[4-(6,7-dimethoxy-quinolin-4...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition against autophosphorylation of Fibroblast growth factor receptor 2 in the human scirrhous gastric carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed