Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M2 and M4 (Homo sapiens (Human)) | BDBM50006243![]() (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.45E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Cavia porcellus) | BDBM50229871![]() (CHEMBL316804) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.91E+3 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Cavia porcellus) | BDBM50006243![]() (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 and M4 (Homo sapiens (Human)) | BDBM50006243![]() (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 and M4 (Homo sapiens (Human)) | BDBM50229871![]() (CHEMBL316804) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.14E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Cavia porcellus) | BDBM50006243![]() (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 and M4 (Homo sapiens (Human)) | BDBM50229871![]() (CHEMBL316804) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Cavia porcellus) | BDBM50229871![]() (CHEMBL316804) | MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.07E+4 | n/a | n/a | n/a | n/a | n/a |
C.N.R.-Centro Studio Sostanze Organiche Naturali Curated by ChEMBL | Assay Description Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysis | J Med Chem 35: 3102-10 (1992) Article DOI: 10.1021/jm00095a003 BindingDB Entry DOI: 10.7270/Q25Q4ZB0 | |||||||||||
More data for this Ligand-Target Pair |