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PubMed code 1507209

Compile data set for download or QSAR
Found 7 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM22881
PNG
(5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine | Am...)
Show SMILES Cc1nc(N)sc1CCN
Show InChI InChI=1S/C6H11N3S/c1-4-5(2-3-7)10-6(8)9-4/h2-3,7H2,1H3,(H2,8,9)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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PubMed
n/an/an/a 5.01E+3n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM7966
PNG
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Show SMILES NCCc1cnc[nH]1
Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
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CHEMBL
DrugBank
MMDB
PC cid
PC sid
UniChem

Patents


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PubMed
n/an/an/a 6.92E+4n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM22883
PNG
(CHEMBL12344 | Dimaprit | [3-(carbamimidoylsulfanyl...)
Show SMILES CN(C)CCCSC(N)=N
Show InChI InChI=1S/C6H15N3S/c1-9(2)4-3-5-10-6(7)8/h3-5H2,1-2H3,(H3,7,8)
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KEGG
PC cid
PC sid
UniChem

Patents

PubMed
n/an/an/a 2.63E+4n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50421967
PNG
(CHEMBL111215)
Show SMILES NCCc1cnc(N)s1
Show InChI InChI=1S/C5H9N3S/c6-2-1-4-3-8-5(7)9-4/h3H,1-2,6H2,(H2,7,8)
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PubMed
n/an/an/a 1.51E+4n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50421968
PNG
(CHEMBL540311)
Show SMILES Cc1ncsc1CCN
Show InChI InChI=1S/C6H10N2S/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3
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PC cid
PC sid
UniChem

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PubMed
n/an/an/a 3.55E+5n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50421966
PNG
(CHEMBL553981)
Show SMILES Cc1nc(C)c(CCN)s1
Show InChI InChI=1S/C7H12N2S/c1-5-7(3-4-8)10-6(2)9-5/h3-4,8H2,1-2H3
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PC cid
PC sid
UniChem
PubMed
n/an/an/a 1.74E+5n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM50421965
PNG
(CHEMBL324864)
Show SMILES NCCc1csc(N)n1
Show InChI InChI=1S/C5H9N3S/c6-2-1-4-3-9-5(7)8-4/h3H,1-2,6H2,(H2,7,8)
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/a 1.10E+5n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%