Affinity Data by PubMed id=1517742

PubMed code 1517742

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50292544 (3,4,6,7-tetrahydroxyxanthone \| CHEMBL477740) Show SMILES Oc1ccc2c(oc3cc(O)c(O)cc3c2=O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE by Lineweaver-Burk plot				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50292547 (1,3,5,6-tetrahydroxyxanthone \| 1,3,5,6-tetrahydrox...) Show SMILES Oc1cc(O)c2c(c1)oc1c(O)c(O)ccc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.42E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE by Lineweaver-Burk plot				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50292546 (3,4,5,6-tetrahydroxyxanthone \| CHEMBL477921 \| US91...) Show SMILES Oc1ccc2c(oc3c(O)c(O)ccc3c2=O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE by Lineweaver-Burk plot				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE by Lineweaver-Burk plot				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50292544 (3,4,6,7-tetrahydroxyxanthone \| CHEMBL477740) Show SMILES Oc1ccc2c(oc3cc(O)c(O)cc3c2=O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50292547 (1,3,5,6-tetrahydroxyxanthone \| 1,3,5,6-tetrahydrox...) Show SMILES Oc1cc(O)c2c(c1)oc1c(O)c(O)ccc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50292546 (3,4,5,6-tetrahydroxyxanthone \| CHEMBL477921 \| US91...) Show SMILES Oc1ccc2c(oc3c(O)c(O)ccc3c2=O)c1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.39E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50155447 (1,3,6,7-Tetrahydroxy-xanthen-9-one \| 1,3,6,7-tetra...) Show SMILES Oc1cc(O)c2c(c1)oc1cc(O)c(O)cc1c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	Purchase CHEBI CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50292545 (2,3,6,7-Tethrahydroxyxanthone \| CHEMBL12700) Show SMILES Oc1cc2oc3cc(O)c(O)cc3c(=O)c2cc1O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.69E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ACE				J Nat Prod 55: 691-695 (1992) Article DOI: 10.1021/np50083a025 BindingDB Entry DOI: 10.7270/Q21C1WXZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%