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PubMed code 15293988

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (human))
BDBM31284
PNG
(CHEMBL361676 | NSC 279287)
Show SMILES CC(C)Oc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(cc1)N=Nc1c(O)n(-c2ccccc2)n(-c2ccccc2)c1=O
Show InChI InChI=1S/C31H27N5O6S/c1-21(2)42-26-17-13-22(14-18-26)29(37)34-43(40,41)27-19-15-23(16-20-27)32-33-28-30(38)35(24-9-5-3-6-10-24)36(31(28)39)25-11-7-4-8-12-25/h3-21,38H,1-2H3,(H,34,37)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.18E+4n/an/an/an/a7.637



Virginia Commonwealth University



Assay Description
ELISA plates were coated with equivalent amounts of either glutathione S-transferase (GST) protein or GST-MDM2 (1-188) fusion protein and incubated o...


J Med Chem 47: 4163-5 (2004)


Article DOI: 10.1021/jm034182u
BindingDB Entry DOI: 10.7270/Q2BZ64DP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%