Affinity Data by PubMed id=1533424

PubMed code 1533424

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM50004921 ((R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004917 (3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004925 (CHEMBL284473 \| R-(+)-APD3-Allyl-1-phenyl-2,3,4,5-t...) Show SMILES Oc1cc2CCN(CC=C)C[C@H](c3ccccc3)c2cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004922 (3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-ben...) Show SMILES Oc1cc2C(CN(CC=C)CCc2c(Br)c1O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004918 ((+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES Oc1cc2CCN(CC=C)CC(c3ccccc3)c2cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004923 ((+/-)-SKF-38393 \| 1-Phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES Oc1cc2CCNCC(c3ccccc3)c2cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004917 (3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	336	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004921 ((R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	511	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004922 (3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-ben...) Show SMILES Oc1cc2C(CN(CC=C)CCc2c(Br)c1O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	701	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004925 (CHEMBL284473 \| R-(+)-APD3-Allyl-1-phenyl-2,3,4,5-t...) Show SMILES Oc1cc2CCN(CC=C)C[C@H](c3ccccc3)c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004919 ((R)(+)-BrAPB \| CHEMBL286424 \| S-(-)-6-Br-APD3-Ally...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004918 ((+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-be...) Show SMILES Oc1cc2CCN(CC=C)CC(c3ccccc3)c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004924 (CHEMBL286120 \| S-(-)-APD3-Allyl-1-phenyl-2,3,4,5-t...) Show SMILES Oc1cc2CCN(CC=C)C[C@@H](c3ccccc3)c2cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004919 ((R)(+)-BrAPB \| CHEMBL286424 \| S-(-)-6-Br-APD3-Ally...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004924 (CHEMBL286120 \| S-(-)-APD3-Allyl-1-phenyl-2,3,4,5-t...) Show SMILES Oc1cc2CCN(CC=C)C[C@@H](c3ccccc3)c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50004920 (CHEMBL284746 \| S(-)SKF 383931-Phenyl-2,3,4,5-tetra...) Show SMILES Oc1cc2CCNC[C@@H](c3ccccc3)c2cc1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-SCH- 23390 (0.3 nM) from dopamine receptor D1 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004920 (CHEMBL284746 \| S(-)SKF 383931-Phenyl-2,3,4,5-tetra...) Show SMILES Oc1cc2CCNC[C@@H](c3ccccc3)c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50004923 ((+/-)-SKF-38393 \| 1-Phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES Oc1cc2CCNCC(c3ccccc3)c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Research Biochemicals Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (60 pm) from dopamine receptor D2 in crude membrane fraction of rat brain corpus striatum				J Med Chem 35: 1466-71 (1992) Article DOI: 10.1021/jm00086a016 BindingDB Entry DOI: 10.7270/Q26H4GCW
Research Biochemicals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%