Affinity Data by PubMed id=1534585

PubMed code 1534585

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity on 5-hydroxytryptamine 2 receptor labeled by [125I]DOI				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50005090 (2-(5-Methoxy-benzofuran-3-yl)-1-methyl-ethylamine ...) Show SMILES COc1ccc2occ(CC(C)N)c2c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity on 5-hydroxytryptamine 2 receptor labeled by [125I]DOI				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50005090 (2-(5-Methoxy-benzofuran-3-yl)-1-methyl-ethylamine ...) Show SMILES COc1ccc2occ(CC(C)N)c2c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity on 5-hydroxytryptamine 2 receptor labeled by [125I]DOI				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity of the compound on 5-hydroxytryptamine 1A receptor labeled by [3H]-8-OH-DPAT				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50005091 (CHEMBL62426 \| [2-(5-Methoxy-benzofuran-3-yl)-ethyl...) Show SMILES COc1ccc2occ(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity on 5-hydroxytryptamine 2 receptor labeled by [125I]DOI				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50005091 (CHEMBL62426 \| [2-(5-Methoxy-benzofuran-3-yl)-ethyl...) Show SMILES COc1ccc2occ(CCN(C)C)c2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity of the compound on 5-hydroxytryptamine 1A receptor labeled by [3H]-8-OH-DPAT				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50005090 (2-(5-Methoxy-benzofuran-3-yl)-1-methyl-ethylamine ...) Show SMILES COc1ccc2occ(CC(C)N)c2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	445	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity of the compound on 5-hydroxytryptamine 1A receptor labeled by [3H]-8-OH-DPAT				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50005090 (2-(5-Methoxy-benzofuran-3-yl)-1-methyl-ethylamine ...) Show SMILES COc1ccc2occ(CC(C)N)c2c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	779	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Affinity of the compound on 5-hydroxytryptamine 1A receptor labeled by [3H]-8-OH-DPAT				J Med Chem 35: 2061-4 (1992) Article DOI: 10.1021/jm00089a017 BindingDB Entry DOI: 10.7270/Q2PG1QN7
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%