Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM50005120![]() (CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) (Rattus norvegicus (rat)) | BDBM50132693![]() (4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM50005118![]() ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM50005117![]() ((racemic)5'-(5-Ethanesulfonyl-2-methoxy-phenyl)-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Patents | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards Dopamine receptor D2 using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) (Rattus norvegicus (rat)) | BDBM81774![]() (CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sul...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI PC cid PC sid UniChem Patents Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) (Rattus norvegicus (rat)) | BDBM48320![]() (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 104 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) (Rattus norvegicus (rat)) | BDBM48320![]() (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | 235 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) (Rattus norvegicus (rat)) | BDBM50005120![]() (CHEMBL274491 | N-((2S,3S)-1-Benzyl-2-methyl-pyrrol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM50132693![]() (4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) (Rattus norvegicus (rat)) | BDBM50005118![]() ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM81774![]() (CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sul...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a) (Rattus norvegicus (rat)) | BDBM81774![]() (CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sul...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEBI PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 233 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM48320![]() (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM50005121![]() ((R)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Lund Curated by ChEMBL | Assay Description Inhibitory concentration required for displacing radioligand [3H]SPI from Dopamine receptor D2 | J Med Chem 35: 2355-63 (1992) Article DOI: 10.1021/jm00091a002 BindingDB Entry DOI: 10.7270/Q2R2120B | |||||||||||
More data for this Ligand-Target Pair |