Compile Data Set for Download or QSAR
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Found 44 Enz. Inhib. hit(s) with all data for entry = 50015296
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154039(2-Amino-1-[3-(5-bromo-4-phenyl-1H-imidazol-2-yl)-3...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154035((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154035((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154036((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154042(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi:  5.20nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154039(2-Amino-1-[3-(5-bromo-4-phenyl-1H-imidazol-2-yl)-3...)
Affinity DataKi:  12nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154035((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...)
Affinity DataKi:  20.7nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154035((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...)
Affinity DataKi:  20.7nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataKi:  22nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154037(2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phen...)
Affinity DataKi:  23nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi:  50nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154036((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...)
Affinity DataKi:  55nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154042(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataKi:  69nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154037(2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phen...)
Affinity DataKi: >100nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154038(2-Amino-1-[2-(4-propyl-1H-imidazol-2-yl)-2,3-dihyd...)
Affinity DataKi: >100nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154038(2-Amino-1-[2-(4-propyl-1H-imidazol-2-yl)-2,3-dihyd...)
Affinity DataKi: >100nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154036((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...)
Affinity DataKi:  124nMAssay Description:Binding affinity for kappa opioid receptor of guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154036((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...)
Affinity DataEC50: >30nMAssay Description:Inhibition of rabbit vas deferens contractionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataEC50:  37nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154037(2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phen...)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154042(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataEC50:  2.12E+3nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154036((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154036((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...)
Affinity DataEC50:  25nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataEC50:  153nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154035((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154039(2-Amino-1-[3-(5-bromo-4-phenyl-1H-imidazol-2-yl)-3...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154034(2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-prop...)
Affinity DataEC50:  85nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154035((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...)
Affinity DataEC50:  1.40nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154042(2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...)
Affinity DataEC50:  82nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154039(2-Amino-1-[3-(5-bromo-4-phenyl-1H-imidazol-2-yl)-3...)
Affinity DataEC50:  1.90nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataEC50:  156nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataEC50:  542nMAssay Description:Inhibition of delta opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataEC50:  58nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154040(2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed