Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50015504
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156754((S)-N-methoxy-4-methyl-3-(4-(methyl(neopentyl)amin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156743((S)-N-hydroxy-4-methyl-3-(4-(methyl(neopentyl)amin...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156750(CHEMBL376506 | DEL-A, 5 | N-methoxy-4-methyl-3-(4-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human p38betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156757((S)-4-methyl-3-(4-(methyl(neopentyl)amino)-6-(pyrr...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156741((S)-3-(4-(isobutyl(methyl)amino)-6-(pyrrolidin-3-y...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156755((S)-N-ethyl-4-methyl-3-(4-(methyl(neopentyl)amino)...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156737((S)-N-isopropyl-4-methyl-3-(4-(methyl(neopentyl)-a...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156738(3-(4-(1,4-diazepan-1-yl)-6-(methyl(neopentyl)amino...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156752(3-(4-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156742(CHEMBL222098 | N-methoxy-4-methyl-3-(4-(methyl(neo...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156756((S)-N-benzyl-4-methyl-3-(4-(methyl(neopentyl)amino...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156747((S)-3-(4-(isobutylamino)-6-(pyrrolidin-3-ylamino)-...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156739(4-methyl-3-(4-(methyl(2-phenylpropyl)amino)-6-((S)...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156746((S)-N-cyclopentyl-4-methyl-3-(4-(methyl(neopentyl)...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156749((S)-3-(4-(4-fluorophenethylamino)-6-(pyrrolidin-3-...)
Affinity DataIC50:  227nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156744((S)-3-(4-(cyclohexyl(methyl)amino)-6-(pyrrolidin-3...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156748((S)-N-(2-methoxyethyl)-4-methyl-3-(4-(methyl(neope...)
Affinity DataIC50:  264nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156745((S)-methyl-4-methyl-3-(4-(methyl(neopentyl)amino)-...)
Affinity DataIC50:  346nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156753(4-methyl-3-(4-(methyl(neopentyl)amino)-6-(4-methyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156736(3-(4-(1,4-diazepan-1-yl)-6-(((1S,2R,5S)-6,6-dimeth...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156751(3-(4-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50156740(3-(4-amino-6-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1....)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IKK2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16316(3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-met...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Zap70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed