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PubMed code 1573640

Compile data set for download or QSAR
Found 54 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholecystokinin receptor


(RAT)
BDBM50449787
PNG
(CHEMBL2062154 | PD-134308)
Show SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1
Show InChI InChI=1S/C35H42N4O6/c1-35(18-26-19-36-28-10-6-5-9-27(26)28,39-34(44)45-32-24-14-21-13-22(16-24)17-25(32)15-21)33(43)37-20-29(23-7-3-2-4-8-23)38-30(40)11-12-31(41)42/h2-10,19,21-22,24-25,29,32,36H,11-18,20H2,1H3,(H,37,43)(H,38,40)(H,39,44)(H,41,42)/t21-,22+,24-,25+,29-,32?,35+/m0/s1
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n/an/a 1.70n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005823
PNG
(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C31H37N3O3/c1-31(18-25-19-33-27-10-6-5-9-26(25)27,29(35)32-12-11-20-7-3-2-4-8-20)34-30(36)37-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,33H,11-18H2,1H3,(H,32,35)(H,34,36)/t21-,22+,23-,24+,28?,31?
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n/an/a 32n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005813
PNG
(3-{2-[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-ind...)
Show SMILES COC(=O)C=CC(=O)N[C@H](COC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)c1ccccc1
Show InChI InChI=1S/C36H41N3O7/c1-36(19-27-20-37-29-11-7-6-10-28(27)29,39-35(43)46-33-25-15-22-14-23(17-25)18-26(33)16-22)34(42)45-21-30(24-8-4-3-5-9-24)38-31(40)12-13-32(41)44-2/h3-13,20,22-23,25-26,30,33,37H,14-19,21H2,1-2H3,(H,38,40)(H,39,43)/t22-,23+,25-,26+,30-,33?,36?/m1/s1
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n/an/a 39n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005816
PNG
(CHEMBL284361 | N-{2-[2-(Adamantan-2-yloxycarbonyla...)
Show SMILES COC(=O)CCC(=O)N[C@H](COC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)c1ccccc1
Show InChI InChI=1S/C36H43N3O7/c1-36(19-27-20-37-29-11-7-6-10-28(27)29,39-35(43)46-33-25-15-22-14-23(17-25)18-26(33)16-22)34(42)45-21-30(24-8-4-3-5-9-24)38-31(40)12-13-32(41)44-2/h3-11,20,22-23,25-26,30,33,37H,12-19,21H2,1-2H3,(H,38,40)(H,39,43)/t22-,23+,25-,26+,30-,33?,36?/m1/s1
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n/an/a 71n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005822
PNG
(CHEMBL36443 | [2-(1H-Indol-3-yl)-1-methyl-1-(methy...)
Show SMILES CN(CCc1ccccc1)C(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H39N3O3/c1-32(19-26-20-33-28-11-7-6-10-27(26)28,30(36)35(2)13-12-21-8-4-3-5-9-21)34-31(37)38-29-24-15-22-14-23(17-24)18-25(29)16-22/h3-11,20,22-25,29,33H,12-19H2,1-2H3,(H,34,37)/t22-,23+,24-,25+,29?,32?
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n/an/a 123n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005815
PNG
(CHEMBL280502 | [1-(2-Hydroxymethyl-3-phenyl-propio...)
Show SMILES OCC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O4/c35-18-25(11-19-6-2-1-3-7-19)30(36)33-28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-12-20-10-21(14-22)15-23(29)13-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 317n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005816
PNG
(CHEMBL284361 | N-{2-[2-(Adamantan-2-yloxycarbonyla...)
Show SMILES COC(=O)CCC(=O)N[C@H](COC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)c1ccccc1
Show InChI InChI=1S/C36H43N3O7/c1-36(19-27-20-37-29-11-7-6-10-28(27)29,39-35(43)46-33-25-15-22-14-23(17-25)18-26(33)16-22)34(42)45-21-30(24-8-4-3-5-9-24)38-31(40)12-13-32(41)44-2/h3-11,20,22-23,25-26,30,33,37H,12-19,21H2,1-2H3,(H,38,40)(H,39,43)/t22-,23+,25-,26+,30-,33?,36?/m1/s1
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n/an/a 351n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005813
PNG
(3-{2-[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-ind...)
Show SMILES COC(=O)C=CC(=O)N[C@H](COC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)c1ccccc1
Show InChI InChI=1S/C36H41N3O7/c1-36(19-27-20-37-29-11-7-6-10-28(27)29,39-35(43)46-33-25-15-22-14-23(17-25)18-26(33)16-22)34(42)45-21-30(24-8-4-3-5-9-24)38-31(40)12-13-32(41)44-2/h3-13,20,22-23,25-26,30,33,37H,14-19,21H2,1-2H3,(H,38,40)(H,39,43)/t22-,23+,25-,26+,30-,33?,36?/m1/s1
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n/an/a 394n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005831
PNG
(2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-y...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)OCCc1ccccc1
Show InChI InChI=1S/C31H36N2O4/c1-31(18-25-19-32-27-10-6-5-9-26(25)27,29(34)36-12-11-20-7-3-2-4-8-20)33-30(35)37-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,32H,11-18H2,1H3,(H,33,35)/t21-,22+,23-,24+,28?,31?
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Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005812
PNG
(CHEMBL285880 | [2-Hydroxy-1-(1H-indol-3-ylmethyl)-...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(O)CCCc1ccccc1
Show InChI InChI=1S/C32H40N2O3/c1-32(19-26-20-33-28-12-6-5-11-27(26)28,29(35)13-7-10-21-8-3-2-4-9-21)34-31(36)37-30-24-15-22-14-23(17-24)18-25(30)16-22/h2-6,8-9,11-12,20,22-25,29-30,33,35H,7,10,13-19H2,1H3,(H,34,36)/t22-,23+,24-,25+,29?,30?,32?
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n/an/a 595n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005812
PNG
(CHEMBL285880 | [2-Hydroxy-1-(1H-indol-3-ylmethyl)-...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(O)CCCc1ccccc1
Show InChI InChI=1S/C32H40N2O3/c1-32(19-26-20-33-28-12-6-5-11-27(26)28,29(35)13-7-10-21-8-3-2-4-9-21)34-31(36)37-30-24-15-22-14-23(17-24)18-25(30)16-22/h2-6,8-9,11-12,20,22-25,29-30,33,35H,7,10,13-19H2,1H3,(H,34,36)/t22-,23+,24-,25+,29?,30?,32?
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n/an/a 595n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005823
PNG
(CHEMBL291033 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C31H37N3O3/c1-31(18-25-19-33-27-10-6-5-9-26(25)27,29(35)32-12-11-20-7-3-2-4-8-20)34-30(36)37-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,33H,11-18H2,1H3,(H,32,35)(H,34,36)/t21-,22+,23-,24+,28?,31?
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n/an/a 640n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005810
PNG
(CHEMBL286442 | [2-(1H-Indol-3-yl)-1-(2-phenethyl-4...)
Show SMILES O=C(NC(Cc1c[nH]c2ccccc12)C1CN=C(CCc2ccccc2)S1)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H37N3O2S/c36-32(37-31-23-13-21-12-22(15-23)16-24(31)14-21)35-28(17-25-18-33-27-9-5-4-8-26(25)27)29-19-34-30(38-29)11-10-20-6-2-1-3-7-20/h1-9,18,21-24,28-29,31,33H,10-17,19H2,(H,35,36)/t21-,22+,23-,24+,28?,29?,31?
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n/an/a 708n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005810
PNG
(CHEMBL286442 | [2-(1H-Indol-3-yl)-1-(2-phenethyl-4...)
Show SMILES O=C(NC(Cc1c[nH]c2ccccc12)C1CN=C(CCc2ccccc2)S1)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H37N3O2S/c36-32(37-31-23-13-21-12-22(15-23)16-24(31)14-21)35-28(17-25-18-33-27-9-5-4-8-26(25)27)29-19-34-30(38-29)11-10-20-6-2-1-3-7-20/h1-9,18,21-24,28-29,31,33H,10-17,19H2,(H,35,36)/t21-,22+,23-,24+,28?,29?,31?
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n/an/a 708n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005822
PNG
(CHEMBL36443 | [2-(1H-Indol-3-yl)-1-methyl-1-(methy...)
Show SMILES CN(CCc1ccccc1)C(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H39N3O3/c1-32(19-26-20-33-28-11-7-6-10-27(26)28,30(36)35(2)13-12-21-8-4-3-5-9-21)34-31(37)38-29-24-15-22-14-23(17-24)18-25(29)16-22/h3-11,20,22-25,29,33H,12-19H2,1-2H3,(H,34,37)/t22-,23+,24-,25+,29?,32?
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n/an/a 757n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50368603
PNG
(CHEMBL1237153)
Show SMILES OCC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O4/c35-18-25(11-19-6-2-1-3-7-19)30(36)33-28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-12-20-10-21(14-22)15-23(29)13-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 780n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005826
PNG
(CHEMBL286843 | [2-(1H-Indol-3-yl)-1-methyl-1-(2-ph...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C1SC(CCc2ccccc2)C=N1
Show InChI InChI=1S/C33H39N3O2S/c1-33(18-26-19-34-29-10-6-5-9-28(26)29,31-35-20-27(39-31)12-11-21-7-3-2-4-8-21)36-32(37)38-30-24-14-22-13-23(16-24)17-25(30)15-22/h2-10,19-20,22-25,27,30-31,34H,11-18H2,1H3,(H,36,37)/t22-,23+,24-,25+,27?,30?,31?,33?
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Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005817
PNG
(CHEMBL287682 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=S)NCCc1ccccc1
Show InChI InChI=1S/C31H37N3O2S/c1-31(18-25-19-33-27-10-6-5-9-26(25)27,29(37)32-12-11-20-7-3-2-4-8-20)34-30(35)36-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,33H,11-18H2,1H3,(H,32,37)(H,34,35)/t21-,22+,23-,24+,28?,31?
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n/an/a 808n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005826
PNG
(CHEMBL286843 | [2-(1H-Indol-3-yl)-1-methyl-1-(2-ph...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C1SC(CCc2ccccc2)C=N1
Show InChI InChI=1S/C33H39N3O2S/c1-33(18-26-19-34-29-10-6-5-9-28(26)29,31-35-20-27(39-31)12-11-21-7-3-2-4-8-21)36-32(37)38-30-24-14-22-13-23(16-24)17-25(30)15-22/h2-10,19-20,22-25,27,30-31,34H,11-18H2,1H3,(H,36,37)/t22-,23+,24-,25+,27?,30?,31?,33?
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n/an/a 827n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005811
PNG
(CHEMBL285049 | [1-(1-Hydroxymethyl-2-phenyl-ethylc...)
Show SMILES OCC(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O4/c35-18-25(15-19-6-2-1-3-7-19)33-30(36)28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 852n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005829
PNG
(6-{[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol...)
Show SMILES CCOC(=O)CCCCCC(=O)N(CCc1ccccc1)CC(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C40H53N3O5/c1-3-47-37(45)17-9-5-8-16-36(44)43(19-18-28-12-6-4-7-13-28)27-40(2,25-33-26-41-35-15-11-10-14-34(33)35)42-39(46)48-38-31-21-29-20-30(23-31)24-32(38)22-29/h4,6-7,10-15,26,29-32,38,41H,3,5,8-9,16-25,27H2,1-2H3,(H,42,46)/t29-,30+,31-,32+,38?,40?
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n/an/a 863n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005828
PNG
(2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-y...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)SCCc1ccccc1
Show InChI InChI=1S/C31H36N2O3S/c1-31(18-25-19-32-27-10-6-5-9-26(25)27,29(34)37-12-11-20-7-3-2-4-8-20)33-30(35)36-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,32H,11-18H2,1H3,(H,33,35)/t21-,22+,23-,24+,28?,31?
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n/an/a 932n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50368603
PNG
(CHEMBL1237153)
Show SMILES OCC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O4/c35-18-25(11-19-6-2-1-3-7-19)30(36)33-28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-12-20-10-21(14-22)15-23(29)13-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 976n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005824
PNG
(CHEMBL288037 | [1-[(Acetyl-phenethyl-amino)-methyl...)
Show SMILES CC(=O)N(CCc1ccccc1)CC(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C33H41N3O3/c1-22(37)36(13-12-23-8-4-3-5-9-23)21-33(2,19-28-20-34-30-11-7-6-10-29(28)30)35-32(38)39-31-26-15-24-14-25(17-26)18-27(31)16-24/h3-11,20,24-27,31,34H,12-19,21H2,1-2H3,(H,35,38)/t24-,25+,26-,27+,31?,33?
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n/an/a 1.06E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005831
PNG
(2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-y...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)OCCc1ccccc1
Show InChI InChI=1S/C31H36N2O4/c1-31(18-25-19-32-27-10-6-5-9-26(25)27,29(34)36-12-11-20-7-3-2-4-8-20)33-30(35)37-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,32H,11-18H2,1H3,(H,33,35)/t21-,22+,23-,24+,28?,31?
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n/an/a 1.07E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005814
PNG
(CHEMBL422941 | [1-[(1-Hydroxymethyl-2-phenyl-ethyl...)
Show SMILES CN(C(CO)Cc1ccccc1)C(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H39N3O4/c1-35(26(19-36)16-20-7-3-2-4-8-20)31(37)29(17-25-18-33-28-10-6-5-9-27(25)28)34-32(38)39-30-23-12-21-11-22(14-23)15-24(30)13-21/h2-10,18,21-24,26,29-30,33,36H,11-17,19H2,1H3,(H,34,38)/t21-,22+,23-,24+,26?,29?,30?
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n/an/a 1.08E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005811
PNG
(CHEMBL285049 | [1-(1-Hydroxymethyl-2-phenyl-ethylc...)
Show SMILES OCC(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O4/c35-18-25(15-19-6-2-1-3-7-19)33-30(36)28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 1.08E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005825
PNG
(CHEMBL445094 | N-[2-(Adamantan-2-yloxycarbonylamin...)
Show SMILES CC(CN(CCc1ccccc1)C(=O)CCC(O)=O)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C35H43N3O5/c1-35(20-28-21-36-30-10-6-5-9-29(28)30,37-34(42)43-33-26-16-24-15-25(18-26)19-27(33)17-24)22-38(31(39)11-12-32(40)41)14-13-23-7-3-2-4-8-23/h2-10,21,24-27,33,36H,11-20,22H2,1H3,(H,37,42)(H,40,41)/t24-,25+,26-,27+,33?,35?
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n/an/a 1.08E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005809
PNG
(CHEMBL35555 | [2-(1H-Indol-3-yl)-1-methyl-1-(phene...)
Show SMILES CC(CNCCc1ccccc1)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H39N3O2/c1-31(20-32-12-11-21-7-3-2-4-8-21,18-26-19-33-28-10-6-5-9-27(26)28)34-30(35)36-29-24-14-22-13-23(16-24)17-25(29)15-22/h2-10,19,22-25,29,32-33H,11-18,20H2,1H3,(H,34,35)/t22-,23+,24-,25+,29?,31?
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n/an/a 1.08E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005828
PNG
(2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-y...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)SCCc1ccccc1
Show InChI InChI=1S/C31H36N2O3S/c1-31(18-25-19-32-27-10-6-5-9-26(25)27,29(34)37-12-11-20-7-3-2-4-8-20)33-30(35)36-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,32H,11-18H2,1H3,(H,33,35)/t21-,22+,23-,24+,28?,31?
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n/an/a 1.19E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005812
PNG
(CHEMBL285880 | [2-Hydroxy-1-(1H-indol-3-ylmethyl)-...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(O)CCCc1ccccc1
Show InChI InChI=1S/C32H40N2O3/c1-32(19-26-20-33-28-12-6-5-11-27(26)28,29(35)13-7-10-21-8-3-2-4-9-21)34-31(36)37-30-24-15-22-14-23(17-24)18-25(30)16-22/h2-6,8-9,11-12,20,22-25,29-30,33,35H,7,10,13-19H2,1H3,(H,34,36)/t22-,23+,24-,25+,29?,30?,32?
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n/an/a 1.23E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005815
PNG
(CHEMBL280502 | [1-(2-Hydroxymethyl-3-phenyl-propio...)
Show SMILES OCC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O4/c35-18-25(11-19-6-2-1-3-7-19)30(36)33-28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(37)38-29-22-12-20-10-21(14-22)15-23(29)13-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,36)(H,34,37)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 1.23E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005818
PNG
(CHEMBL285762 | [1-[(1-Hydroxymethyl-2-phenyl-ethyl...)
Show SMILES OCC(Cc1ccccc1)NCC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H39N3O3/c35-19-27(15-20-6-2-1-3-7-20)32-18-26(16-25-17-33-29-9-5-4-8-28(25)29)34-31(36)37-30-23-11-21-10-22(13-23)14-24(30)12-21/h1-9,17,21-24,26-27,30,32-33,35H,10-16,18-19H2,(H,34,36)/t21-,22+,23-,24+,26?,27?,30?
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n/an/a 1.25E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005825
PNG
(CHEMBL445094 | N-[2-(Adamantan-2-yloxycarbonylamin...)
Show SMILES CC(CN(CCc1ccccc1)C(=O)CCC(O)=O)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C35H43N3O5/c1-35(20-28-21-36-30-10-6-5-9-29(28)30,37-34(42)43-33-26-16-24-15-25(18-26)19-27(33)17-24)22-38(31(39)11-12-32(40)41)14-13-23-7-3-2-4-8-23/h2-10,21,24-27,33,36H,11-20,22H2,1H3,(H,37,42)(H,40,41)/t24-,25+,26-,27+,33?,35?
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n/an/a 1.27E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005824
PNG
(CHEMBL288037 | [1-[(Acetyl-phenethyl-amino)-methyl...)
Show SMILES CC(=O)N(CCc1ccccc1)CC(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C33H41N3O3/c1-22(37)36(13-12-23-8-4-3-5-9-23)21-33(2,19-28-20-34-30-11-7-6-10-29(28)30)35-32(38)39-31-26-15-24-14-25(17-26)18-27(31)16-24/h3-11,20,24-27,31,34H,12-19,21H2,1-2H3,(H,35,38)/t24-,25+,26-,27+,31?,33?
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n/an/a 1.31E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005814
PNG
(CHEMBL422941 | [1-[(1-Hydroxymethyl-2-phenyl-ethyl...)
Show SMILES CN(C(CO)Cc1ccccc1)C(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H39N3O4/c1-35(26(19-36)16-20-7-3-2-4-8-20)31(37)29(17-25-18-33-28-10-6-5-9-27(25)28)34-32(38)39-30-23-12-21-11-22(14-23)15-24(30)13-21/h2-10,18,21-24,26,29-30,33,36H,11-17,19H2,1H3,(H,34,38)/t21-,22+,23-,24+,26?,29?,30?
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n/an/a 1.46E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005817
PNG
(CHEMBL287682 | [2-(1H-Indol-3-yl)-1-methyl-1-phene...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=S)NCCc1ccccc1
Show InChI InChI=1S/C31H37N3O2S/c1-31(18-25-19-33-27-10-6-5-9-26(25)27,29(37)32-12-11-20-7-3-2-4-8-20)34-30(35)36-28-23-14-21-13-22(16-23)17-24(28)15-21/h2-10,19,21-24,28,33H,11-18H2,1H3,(H,32,37)(H,34,35)/t21-,22+,23-,24+,28?,31?
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n/an/a 1.50E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005830
PNG
(CHEMBL34300 | [1-(1-Hydroxymethyl-2-phenyl-ethylth...)
Show SMILES OCC(Cc1ccccc1)NC(=S)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O3S/c35-18-25(15-19-6-2-1-3-7-19)33-30(38)28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(36)37-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,38)(H,34,36)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 1.59E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005808
PNG
(CHEMBL286664 | N-[2-(Adamantan-2-yloxycarbonylamin...)
Show SMILES CCOC(=O)CCC(=O)N(CCc1ccccc1)CC(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C37H47N3O5/c1-3-44-34(42)14-13-33(41)40(16-15-25-9-5-4-6-10-25)24-37(2,22-30-23-38-32-12-8-7-11-31(30)32)39-36(43)45-35-28-18-26-17-27(20-28)21-29(35)19-26/h4-12,23,26-29,35,38H,3,13-22,24H2,1-2H3,(H,39,43)/t26-,27+,28-,29+,35?,37?
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n/an/a 1.63E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005819
PNG
(2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-y...)
Show SMILES OCC(Cc1ccccc1)OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H36N2O5/c34-18-25(15-19-6-2-1-3-7-19)37-30(35)28(16-24-17-32-27-9-5-4-8-26(24)27)33-31(36)38-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,34H,10-16,18H2,(H,33,36)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 1.89E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005830
PNG
(CHEMBL34300 | [1-(1-Hydroxymethyl-2-phenyl-ethylth...)
Show SMILES OCC(Cc1ccccc1)NC(=S)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H37N3O3S/c35-18-25(15-19-6-2-1-3-7-19)33-30(38)28(16-24-17-32-27-9-5-4-8-26(24)27)34-31(36)37-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,35H,10-16,18H2,(H,33,38)(H,34,36)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 1.98E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005810
PNG
(CHEMBL286442 | [2-(1H-Indol-3-yl)-1-(2-phenethyl-4...)
Show SMILES O=C(NC(Cc1c[nH]c2ccccc12)C1CN=C(CCc2ccccc2)S1)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H37N3O2S/c36-32(37-31-23-13-21-12-22(15-23)16-24(31)14-21)35-28(17-25-18-33-27-9-5-4-8-26(25)27)29-19-34-30(38-29)11-10-20-6-2-1-3-7-20/h1-9,18,21-24,28-29,31,33H,10-17,19H2,(H,35,36)/t21-,22+,23-,24+,28?,29?,31?
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n/an/a 2.51E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005810
PNG
(CHEMBL286442 | [2-(1H-Indol-3-yl)-1-(2-phenethyl-4...)
Show SMILES O=C(NC(Cc1c[nH]c2ccccc12)C1CN=C(CCc2ccccc2)S1)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H37N3O2S/c36-32(37-31-23-13-21-12-22(15-23)16-24(31)14-21)35-28(17-25-18-33-27-9-5-4-8-26(25)27)29-19-34-30(38-29)11-10-20-6-2-1-3-7-20/h1-9,18,21-24,28-29,31,33H,10-17,19H2,(H,35,36)/t21-,22+,23-,24+,28?,29?,31?
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n/an/a 2.58E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005812
PNG
(CHEMBL285880 | [2-Hydroxy-1-(1H-indol-3-ylmethyl)-...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(O)CCCc1ccccc1
Show InChI InChI=1S/C32H40N2O3/c1-32(19-26-20-33-28-12-6-5-11-27(26)28,29(35)13-7-10-21-8-3-2-4-9-21)34-31(36)37-30-24-15-22-14-23(17-24)18-25(30)16-22/h2-6,8-9,11-12,20,22-25,29-30,33,35H,7,10,13-19H2,1H3,(H,34,36)/t22-,23+,24-,25+,29?,30?,32?
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n/an/a 2.62E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005819
PNG
(2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-y...)
Show SMILES OCC(Cc1ccccc1)OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H36N2O5/c34-18-25(15-19-6-2-1-3-7-19)37-30(35)28(16-24-17-32-27-9-5-4-8-26(24)27)33-31(36)38-29-22-11-20-10-21(13-22)14-23(29)12-20/h1-9,17,20-23,25,28-29,32,34H,10-16,18H2,(H,33,36)/t20-,21+,22-,23+,25?,28?,29?
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n/an/a 2.95E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005829
PNG
(6-{[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol...)
Show SMILES CCOC(=O)CCCCCC(=O)N(CCc1ccccc1)CC(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C40H53N3O5/c1-3-47-37(45)17-9-5-8-16-36(44)43(19-18-28-12-6-4-7-13-28)27-40(2,25-33-26-41-35-15-11-10-14-34(33)35)42-39(46)48-38-31-21-29-20-30(23-31)24-32(38)22-29/h4,6-7,10-15,26,29-32,38,41H,3,5,8-9,16-25,27H2,1-2H3,(H,42,46)/t29-,30+,31-,32+,38?,40?
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n/an/a 3.53E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005827
PNG
(CHEMBL34422 | [1-(1H-Indol-3-ylmethyl)-1-methyl-5-...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)\C=C\CCc1ccccc1
Show InChI InChI=1S/C32H38N2O2/c1-32(14-8-7-11-22-9-3-2-4-10-22,20-27-21-33-29-13-6-5-12-28(27)29)34-31(35)36-30-25-16-23-15-24(18-25)19-26(30)17-23/h2-6,8-10,12-14,21,23-26,30,33H,7,11,15-20H2,1H3,(H,34,35)/b14-8+/t23-,24+,25-,26+,30?,32?
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n/an/a 3.62E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005808
PNG
(CHEMBL286664 | N-[2-(Adamantan-2-yloxycarbonylamin...)
Show SMILES CCOC(=O)CCC(=O)N(CCc1ccccc1)CC(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C37H47N3O5/c1-3-44-34(42)14-13-33(41)40(16-15-25-9-5-4-6-10-25)24-37(2,22-30-23-38-32-12-8-7-11-31(30)32)39-36(43)45-35-28-18-26-17-27(20-28)21-29(35)19-26/h4-12,23,26-29,35,38H,3,13-22,24H2,1-2H3,(H,39,43)/t26-,27+,28-,29+,35?,37?
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n/an/a 3.67E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005809
PNG
(CHEMBL35555 | [2-(1H-Indol-3-yl)-1-methyl-1-(phene...)
Show SMILES CC(CNCCc1ccccc1)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H39N3O2/c1-31(20-32-12-11-21-7-3-2-4-8-21,18-26-19-33-28-10-6-5-9-27(26)28)34-30(35)36-29-24-14-22-13-23(16-24)17-25(29)15-22/h2-10,19,22-25,29,32-33H,11-18,20H2,1H3,(H,34,35)/t22-,23+,24-,25+,29?,31?
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n/an/a 4.06E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50449787
PNG
(CHEMBL2062154 | PD-134308)
Show SMILES C[C@](Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1
Show InChI InChI=1S/C35H42N4O6/c1-35(18-26-19-36-28-10-6-5-9-27(26)28,39-34(44)45-32-24-14-21-13-22(16-24)17-25(32)15-21)33(43)37-20-29(23-7-3-2-4-8-23)38-30(40)11-12-31(41)42/h2-10,19,21-22,24-25,29,32,36H,11-18,20H2,1H3,(H,37,43)(H,38,40)(H,39,44)(H,41,42)/t21-,22+,24-,25+,29-,32?,35+/m0/s1
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n/an/a 4.30E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005827
PNG
(CHEMBL34422 | [1-(1H-Indol-3-ylmethyl)-1-methyl-5-...)
Show SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)\C=C\CCc1ccccc1
Show InChI InChI=1S/C32H38N2O2/c1-32(14-8-7-11-22-9-3-2-4-10-22,20-27-21-33-29-13-6-5-12-28(27)29)34-31(35)36-30-25-16-23-15-24(18-25)19-26(30)17-23/h2-6,8-10,12-14,21,23-26,30,33H,7,11,15-20H2,1H3,(H,34,35)/b14-8+/t23-,24+,25-,26+,30?,32?
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n/an/a 6.34E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005821
PNG
(CHEMBL286093 | [1-(1H-Indol-3-ylmethyl)-1-methyl-5...)
Show SMILES CC(CCCCc1ccccc1)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H40N2O2/c1-32(14-8-7-11-22-9-3-2-4-10-22,20-27-21-33-29-13-6-5-12-28(27)29)34-31(35)36-30-25-16-23-15-24(18-25)19-26(30)17-23/h2-6,9-10,12-13,21,23-26,30,33H,7-8,11,14-20H2,1H3,(H,34,35)/t23-,24+,25-,26+,30?,32?
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n/an/a 8.69E+3n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(RAT)
BDBM50005818
PNG
(CHEMBL285762 | [1-[(1-Hydroxymethyl-2-phenyl-ethyl...)
Show SMILES OCC(Cc1ccccc1)NCC(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C31H39N3O3/c35-19-27(15-20-6-2-1-3-7-20)32-18-26(16-25-17-33-29-9-5-4-8-28(25)29)34-31(36)37-30-23-11-21-10-22(13-23)14-24(30)12-21/h1-9,17,21-24,26-27,30,32-33,35H,10-16,18-19H2,(H,34,36)/t21-,22+,23-,24+,26?,27?,30?
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n/an/a 1.15E+4n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas


Citation and Details
More data for this
Ligand-Target Pair
Cholecystokinin receptor


(MOUSE)
BDBM50005821
PNG
(CHEMBL286093 | [1-(1H-Indol-3-ylmethyl)-1-methyl-5...)
Show SMILES CC(CCCCc1ccccc1)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
Show InChI InChI=1S/C32H40N2O2/c1-32(14-8-7-11-22-9-3-2-4-10-22,20-27-21-33-29-13-6-5-12-28(27)29)34-31(35)36-30-25-16-23-15-24(18-25)19-26(30)17-23/h2-6,9-10,12-13,21,23-26,30,33H,7-8,11,14-20H2,1H3,(H,34,35)/t23-,24+,25-,26+,30?,32?
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n/an/a 1.95E+4n/an/an/an/an/an/a



Parke-Davis Neuroscience Research Center

Curated by ChEMBL


Assay Description
Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%