Affinity Data by PubMed id=1578487

PubMed code 1578487

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50005795 (2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...) Show SMILES Nc1nc2c(nc(N)[nH]c2=O)n1Cc1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50368609 (CHEMBL604660) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50368611 (CHEMBL604864) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50005916 (2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...) Show SMILES Nc1[nH]c2c(nc(N)[nH]c2=O)c1Cc1ccsc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50368608 (CHEMBL604827) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50368610 (CHEMBL605447) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Ability to inhibit purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50005916 (2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...) Show SMILES Nc1[nH]c2c(nc(N)[nH]c2=O)c1Cc1ccsc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50005924 (2,6-Diamino-7-thiophen-2-ylmethyl-3,5-dihydro-pyrr...) Show SMILES Nc1[nH]c2c(nc(N)[nH]c2=O)c1Cc1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50404028 (CHEMBL2021376) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50005919 (2,6-Diamino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyr...) Show SMILES Nc1[nH]c2c(nc(N)[nH]c2=O)c1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50005918 (2,6-Diamino-7-furan-2-ylmethyl-3,5-dihydro-pyrrolo...) Show SMILES Nc1[nH]c2c(nc(N)[nH]c2=O)c1Cc1ccco1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (human))	BDBM50005921 (2,6-Diamino-7-(2-methoxy-benzyl)-3,5-dihydro-pyrro...) Show SMILES COc1ccccc1Cc1c(N)[nH]c2c1nc(N)[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)				Citation and Details
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%