Affinity Data by PubMed id=1588567

PubMed code 1588567

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic receptor M2 and M3 (RAT)	BDBM50006246 (CHEMBL56734 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@@H]1O[C@H](C[N+](C)(C)C)CC1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound to m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heart				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006245 (CHEMBL59587 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@@H]1O[C@@H](C[N+](C)(C)C)CC1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heart.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) Show SMILES C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M3 of rat sabmandibular glands				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006246 (CHEMBL56734 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@@H]1O[C@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound to m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glands				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006246 (CHEMBL56734 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@@H]1O[C@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound to m-AcChR subtype M1 of rat cerebral cortex				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006245 (CHEMBL59587 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@@H]1O[C@@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype M1 of rat cerebral cortex.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006245 (CHEMBL59587 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@@H]1O[C@@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glands				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006247 (CHEMBL59085 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@H]1O[C@H](C[N+](C)(C)C)CC1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heart.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006244 (CHEMBL294470 \| Trimethyl-(5-methyl-4-oxo-tetrahydr...) Show SMILES C[C@H]1O[C@@H](C[N+](C)(C)C)CC1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M2 of rat heart.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006244 (CHEMBL294470 \| Trimethyl-(5-methyl-4-oxo-tetrahydr...) Show SMILES C[C@H]1O[C@@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glands				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) Show SMILES C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M1 of rat cerebral cortex.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006244 (CHEMBL294470 \| Trimethyl-(5-methyl-4-oxo-tetrahydr...) Show SMILES C[C@H]1O[C@@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype M1 of rat cerebral cortex.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006247 (CHEMBL59085 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@H]1O[C@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype Muscarinic acetylcholine receptor M3 of rat sabmandibular glands				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006243 (((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-...) Show SMILES C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M2 of rat heart.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006247 (CHEMBL59085 \| Trimethyl-(5-methyl-4-oxo-tetrahydro...) Show SMILES C[C@H]1O[C@H](C[N+](C)(C)C)CC1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against m-AcChR subtype M1 of rat cerebral cortex.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006248 ((4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-t...) Show SMILES C[C@H]1O[C@@H](C[N+](C)(C)C)C[C@@H]1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M3 of rat sabmandibular glands				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006248 ((4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-t...) Show SMILES C[C@H]1O[C@@H](C[N+](C)(C)C)C[C@@H]1O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M1 of rat cerebral cortex.				Citation and Details
					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006248 ((4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-t...) Show SMILES C[C@H]1O[C@@H](C[N+](C)(C)C)C[C@@H]1O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.52E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico-Farmaceutico dell'Università Curated by ChEMBL					Assay Description Binding affinity of the compound against muscarinic acetylcholine receptor M2 of rat heart.				Citation and Details
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%