BindingDB logo
myBDB logout

PubMed code 15974575

Compile data set for download or QSAR
Found 127 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410236
PNG
(CHEMBL365913)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-32(53-27(2)58)39(61)52-26-38(60)54-33(18-10-11-20-45)41(63)56-35(22-28-13-6-5-7-14-28)43(65)55-34(19-12-21-49-44(47)48)42(64)57-36(40(62)51-25-37(46)59)23-29-24-50-31-17-9-8-15-30(29)31/h5-9,13-15,17,24,32-36,50H,3-4,10-12,16,18-23,25-26,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,58)(H,54,60)(H,55,65)(H,56,63)(H,57,64)(H4,47,48,49)/t32-,33-,34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.5n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410248
PNG
(CHEMBL186970)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C43H63N11O8/c1-3-4-16-33(50-28(2)55)40(59)49-26-39(58)54(21-11-10-19-44)27-38(57)51-35(22-29-13-6-5-7-14-29)43(62)52-34(18-12-20-45)42(61)53-36(41(60)48-25-37(46)56)23-30-24-47-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,47H,3-4,10-12,16,18-23,25-27,44-45H2,1-2H3,(H2,46,56)(H,48,60)(H,49,59)(H,50,55)(H,51,57)(H,52,62)(H,53,61)/t33-,34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410249
PNG
(CHEMBL373344)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-57(28(2)58)27-39(61)51-26-38(60)53-33(17-10-11-19-45)41(63)55-35(22-29-13-6-5-7-14-29)43(65)54-34(18-12-20-49-44(47)48)42(64)56-36(40(62)52-25-37(46)59)23-30-24-50-32-16-9-8-15-31(30)32/h5-9,13-16,24,33-36,50H,3-4,10-12,17-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,60)(H,54,65)(H,55,63)(H,56,64)(H4,47,48,49)/t33-,34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410241
PNG
(CHEMBL188459)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-38(60)51-26-40(62)57(21-11-10-18-45)28-39(61)53-35(22-30-13-6-5-7-14-30)43(65)54-34(17-12-19-49-44(47)48)42(64)55-36(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,61)(H,54,65)(H,55,64)(H4,47,48,49)/t34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410252
PNG
(CHEMBL190551)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-35(54-30(2)59)42(64)53-27-39(61)55-36(18-10-11-20-46)43(65)56-37(24-31-13-6-5-7-14-31)44(66)58(22-12-21-50-45(48)49)29-41(63)57(28-40(62)52-26-38(47)60)23-19-32-25-51-34-17-9-8-15-33(32)34/h5-9,13-15,17,25,35-37,51H,3-4,10-12,16,18-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,64)(H,54,59)(H,55,61)(H,56,65)(H4,48,49,50)/t35-,36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 79n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410249
PNG
(CHEMBL373344)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-57(28(2)58)27-39(61)51-26-38(60)53-33(17-10-11-19-45)41(63)55-35(22-29-13-6-5-7-14-29)43(65)54-34(18-12-20-49-44(47)48)42(64)56-36(40(62)52-25-37(46)59)23-30-24-50-32-16-9-8-15-31(30)32/h5-9,13-16,24,33-36,50H,3-4,10-12,17-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,60)(H,54,65)(H,55,63)(H,56,64)(H4,47,48,49)/t33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 126n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410239
PNG
(CHEMBL190953)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-40(62)56(21-11-10-19-45)28-39(61)54-36(22-30-13-6-5-7-14-30)42(64)55-35(18-12-20-49-44(47)48)43(65)57(27-38(60)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,58)(H,54,61)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 158n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410248
PNG
(CHEMBL186970)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C43H63N11O8/c1-3-4-16-33(50-28(2)55)40(59)49-26-39(58)54(21-11-10-19-44)27-38(57)51-35(22-29-13-6-5-7-14-29)43(62)52-34(18-12-20-45)42(61)53-36(41(60)48-25-37(46)56)23-30-24-47-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,47H,3-4,10-12,16,18-23,25-27,44-45H2,1-2H3,(H2,46,56)(H,48,60)(H,49,59)(H,50,55)(H,51,57)(H,52,62)(H,53,61)/t33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 158n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410247
PNG
(CHEMBL190080)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C46H69N13O8/c1-3-4-17-36(55-31(2)60)43(65)54-28-40(62)56-37(19-10-11-21-47)44(66)57-38(25-32-14-6-5-7-15-32)45(67)59(23-13-12-22-51-46(49)50)30-42(64)58(29-41(63)53-27-39(48)61)24-20-33-26-52-35-18-9-8-16-34(33)35/h5-9,14-16,18,26,36-38,52H,3-4,10-13,17,19-25,27-30,47H2,1-2H3,(H2,48,61)(H,53,63)(H,54,65)(H,55,60)(H,56,62)(H,57,66)(H4,49,50,51)/t36-,37-,38+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 158n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410251
PNG
(CHEMBL2371835)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-17-34(54-29(2)59)41(63)53-27-39(61)55-35(19-10-11-20-46)43(65)57-37(23-30-14-6-5-7-15-30)44(66)58(22-13-12-21-50-45(48)49)28-40(62)56-36(42(64)52-26-38(47)60)24-31-25-51-33-18-9-8-16-32(31)33/h5-9,14-16,18,25,34-37,51H,3-4,10-13,17,19-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,64)(H,53,63)(H,54,59)(H,55,61)(H,56,62)(H,57,65)(H4,48,49,50)/t34-,35-,36?,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 158n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410236
PNG
(CHEMBL365913)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-32(53-27(2)58)39(61)52-26-38(60)54-33(18-10-11-20-45)41(63)56-35(22-28-13-6-5-7-14-28)43(65)55-34(19-12-21-49-44(47)48)42(64)57-36(40(62)51-25-37(46)59)23-29-24-50-31-17-9-8-15-30(29)31/h5-9,13-15,17,24,32-36,50H,3-4,10-12,16,18-23,25-26,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,58)(H,54,60)(H,55,65)(H,56,63)(H,57,64)(H4,47,48,49)/t32-,33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410261
PNG
(CHEMBL191120)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-25-38(60)54-34(18-10-11-20-45)41(63)56-36(22-29-13-6-5-7-14-29)42(64)55-35(19-12-21-49-44(47)48)43(65)57(27-39(61)51-24-37(46)59)26-30-23-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,23,33-36,50H,3-4,10-12,16,18-22,24-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,58)(H,54,60)(H,55,64)(H,56,63)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 251n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410257
PNG
(CHEMBL188738)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-40(62)53-27-39(61)54-36(17-10-11-19-46)43(65)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(29-41(63)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 251n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410245
PNG
(CHEMBL191063)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-38(60)54-35(18-10-11-19-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)56(21-12-20-49-44(47)48)28-40(62)57(27-39(61)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,58)(H,54,60)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 316n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410237
PNG
(CHEMBL372237)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 316n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410238
PNG
(CHEMBL370321)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-26-38(60)54-34(18-10-11-19-45)42(64)56-36(22-29-13-6-5-7-14-29)43(65)57(21-12-20-49-44(47)48)27-39(61)55-35(41(63)51-25-37(46)59)23-30-24-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,50H,3-4,10-12,16,18-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,63)(H,52,62)(H,53,58)(H,54,60)(H,55,61)(H,56,64)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 398n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410261
PNG
(CHEMBL191120)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-25-38(60)54-34(18-10-11-20-45)41(63)56-36(22-29-13-6-5-7-14-29)42(64)55-35(19-12-21-49-44(47)48)43(65)57(27-39(61)51-24-37(46)59)26-30-23-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,23,33-36,50H,3-4,10-12,16,18-22,24-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,58)(H,54,60)(H,55,64)(H,56,63)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 501n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410243
PNG
(CHEMBL365794)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-36(54-31(2)59)43(65)53-27-41(63)56(21-11-10-19-46)29-40(62)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(28-39(61)52-26-38(47)60)23-18-33-25-51-35-17-9-8-15-34(33)35/h5-9,13-15,17,25,36-37,51H,3-4,10-12,16,18-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,61)(H,53,65)(H,54,59)(H,55,62)(H4,48,49,50)/t36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 501n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410247
PNG
(CHEMBL190080)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C46H69N13O8/c1-3-4-17-36(55-31(2)60)43(65)54-28-40(62)56-37(19-10-11-21-47)44(66)57-38(25-32-14-6-5-7-15-32)45(67)59(23-13-12-22-51-46(49)50)30-42(64)58(29-41(63)53-27-39(48)61)24-20-33-26-52-35-18-9-8-16-34(33)35/h5-9,14-16,18,26,36-38,52H,3-4,10-13,17,19-25,27-30,47H2,1-2H3,(H2,48,61)(H,53,63)(H,54,65)(H,55,60)(H,56,62)(H,57,66)(H4,49,50,51)/t36-,37-,38+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 501n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410239
PNG
(CHEMBL190953)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-40(62)56(21-11-10-19-45)28-39(61)54-36(22-30-13-6-5-7-14-30)42(64)55-35(18-12-20-49-44(47)48)43(65)57(27-38(60)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,58)(H,54,61)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 631n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410247
PNG
(CHEMBL190080)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C46H69N13O8/c1-3-4-17-36(55-31(2)60)43(65)54-28-40(62)56-37(19-10-11-21-47)44(66)57-38(25-32-14-6-5-7-15-32)45(67)59(23-13-12-22-51-46(49)50)30-42(64)58(29-41(63)53-27-39(48)61)24-20-33-26-52-35-18-9-8-16-34(33)35/h5-9,14-16,18,26,36-38,52H,3-4,10-13,17,19-25,27-30,47H2,1-2H3,(H2,48,61)(H,53,63)(H,54,65)(H,55,60)(H,56,62)(H,57,66)(H4,49,50,51)/t36-,37-,38+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 631n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410244
PNG
(CHEMBL275999)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-39(61)52-25-38(60)53-35(17-10-11-18-45)42(64)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(28-40(62)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 794n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410254
PNG
(CHEMBL190203)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 794n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410239
PNG
(CHEMBL190953)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-40(62)56(21-11-10-19-45)28-39(61)54-36(22-30-13-6-5-7-14-30)42(64)55-35(18-12-20-49-44(47)48)43(65)57(27-38(60)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,58)(H,54,61)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 794n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410241
PNG
(CHEMBL188459)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-38(60)51-26-40(62)57(21-11-10-18-45)28-39(61)53-35(22-30-13-6-5-7-14-30)43(65)54-34(17-12-19-49-44(47)48)42(64)55-36(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,61)(H,54,65)(H,55,64)(H4,47,48,49)/t34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 794n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410261
PNG
(CHEMBL191120)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-25-38(60)54-34(18-10-11-20-45)41(63)56-36(22-29-13-6-5-7-14-29)42(64)55-35(19-12-21-49-44(47)48)43(65)57(27-39(61)51-24-37(46)59)26-30-23-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,23,33-36,50H,3-4,10-12,16,18-22,24-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,58)(H,54,60)(H,55,64)(H,56,63)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 794n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410260
PNG
(CHEMBL190427)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-38(60)52-25-41(63)56(21-11-10-18-45)29-40(62)53-36(22-31-13-6-5-7-14-31)42(64)54-35(17-12-19-49-44(47)48)43(65)57(28-39(61)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 794n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410252
PNG
(CHEMBL190551)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-35(54-30(2)59)42(64)53-27-39(61)55-36(18-10-11-20-46)43(65)56-37(24-31-13-6-5-7-14-31)44(66)58(22-12-21-50-45(48)49)29-41(63)57(28-40(62)52-26-38(47)60)23-19-32-25-51-34-17-9-8-15-33(32)34/h5-9,13-15,17,25,35-37,51H,3-4,10-12,16,18-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,64)(H,54,59)(H,55,61)(H,56,65)(H4,48,49,50)/t35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410256
PNG
(CHEMBL190732)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-20-55(32(2)59)28-39(61)53-27-42(64)56(21-11-10-18-46)30-41(63)54-37(24-33-13-6-5-7-14-33)44(66)58(22-12-19-50-45(48)49)31-43(65)57(29-40(62)52-26-38(47)60)23-17-34-25-51-36-16-9-8-15-35(34)36/h5-9,13-16,25,37,51H,3-4,10-12,17-24,26-31,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H4,48,49,50)/t37-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410257
PNG
(CHEMBL188738)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-40(62)53-27-39(61)54-36(17-10-11-19-46)43(65)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(29-41(63)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410241
PNG
(CHEMBL188459)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-38(60)51-26-40(62)57(21-11-10-18-45)28-39(61)53-35(22-30-13-6-5-7-14-30)43(65)54-34(17-12-19-49-44(47)48)42(64)55-36(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,61)(H,54,65)(H,55,64)(H4,47,48,49)/t34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410254
PNG
(CHEMBL190203)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.26E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410254
PNG
(CHEMBL190203)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.59E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410243
PNG
(CHEMBL365794)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-36(54-31(2)59)43(65)53-27-41(63)56(21-11-10-19-46)29-40(62)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(28-39(61)52-26-38(47)60)23-18-33-25-51-35-17-9-8-15-34(33)35/h5-9,13-15,17,25,36-37,51H,3-4,10-12,16,18-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,61)(H,53,65)(H,54,59)(H,55,62)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.59E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410252
PNG
(CHEMBL190551)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-35(54-30(2)59)42(64)53-27-39(61)55-36(18-10-11-20-46)43(65)56-37(24-31-13-6-5-7-14-31)44(66)58(22-12-21-50-45(48)49)29-41(63)57(28-40(62)52-26-38(47)60)23-19-32-25-51-34-17-9-8-15-33(32)34/h5-9,13-15,17,25,35-37,51H,3-4,10-12,16,18-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,64)(H,54,59)(H,55,61)(H,56,65)(H4,48,49,50)/t35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410245
PNG
(CHEMBL191063)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-38(60)54-35(18-10-11-19-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)56(21-12-20-49-44(47)48)28-40(62)57(27-39(61)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,58)(H,54,60)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410251
PNG
(CHEMBL2371835)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-17-34(54-29(2)59)41(63)53-27-39(61)55-35(19-10-11-20-46)43(65)57-37(23-30-14-6-5-7-15-30)44(66)58(22-13-12-21-50-45(48)49)28-40(62)56-36(42(64)52-26-38(47)60)24-31-25-51-33-18-9-8-16-32(31)33/h5-9,14-16,18,25,34-37,51H,3-4,10-13,17,19-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,64)(H,53,63)(H,54,59)(H,55,61)(H,56,62)(H,57,65)(H4,48,49,50)/t34-,35-,36?,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410256
PNG
(CHEMBL190732)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-20-55(32(2)59)28-39(61)53-27-42(64)56(21-11-10-18-46)30-41(63)54-37(24-33-13-6-5-7-14-33)44(66)58(22-12-19-50-45(48)49)31-43(65)57(29-40(62)52-26-38(47)60)23-17-34-25-51-36-16-9-8-15-35(34)36/h5-9,13-16,25,37,51H,3-4,10-12,17-24,26-31,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H4,48,49,50)/t37-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410260
PNG
(CHEMBL190427)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-38(60)52-25-41(63)56(21-11-10-18-45)29-40(62)53-36(22-31-13-6-5-7-14-31)42(64)54-35(17-12-19-49-44(47)48)43(65)57(28-39(61)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410246
PNG
(CHEMBL364711)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-39(61)53-27-42(64)57(22-11-10-19-46)30-41(63)54-37(24-32-13-6-5-7-14-32)43(65)55-36(17-12-20-50-45(48)49)44(66)58(29-40(62)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410260
PNG
(CHEMBL190427)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-38(60)52-25-41(63)56(21-11-10-18-45)29-40(62)53-36(22-31-13-6-5-7-14-31)42(64)54-35(17-12-19-49-44(47)48)43(65)57(28-39(61)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410259
PNG
(CHEMBL189991)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-35(53-30(2)58)42(64)52-25-40(62)55(20-11-10-18-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(27-38(60)51-24-37(46)59)26-32-23-50-34-17-9-8-15-33(32)34/h5-9,13-15,17,23,35-36,50H,3-4,10-12,16,18-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,58)(H,54,61)(H4,47,48,49)/t35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.16E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410238
PNG
(CHEMBL370321)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-26-38(60)54-34(18-10-11-19-45)42(64)56-36(22-29-13-6-5-7-14-29)43(65)57(21-12-20-49-44(47)48)27-39(61)55-35(41(63)51-25-37(46)59)23-30-24-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,50H,3-4,10-12,16,18-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,63)(H,52,62)(H,53,58)(H,54,60)(H,55,61)(H,56,64)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.16E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410244
PNG
(CHEMBL275999)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-39(61)52-25-38(60)53-35(17-10-11-18-45)42(64)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(28-40(62)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.16E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410259
PNG
(CHEMBL189991)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-35(53-30(2)58)42(64)52-25-40(62)55(20-11-10-18-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(27-38(60)51-24-37(46)59)26-32-23-50-34-17-9-8-15-33(32)34/h5-9,13-15,17,23,35-36,50H,3-4,10-12,16,18-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,58)(H,54,61)(H4,47,48,49)/t35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.16E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410257
PNG
(CHEMBL188738)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-40(62)53-27-39(61)54-36(17-10-11-19-46)43(65)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(29-41(63)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.16E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410253
PNG
(CHEMBL371610)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-54(31(2)58)27-38(60)52-25-41(63)55(20-11-10-17-45)29-40(62)53-36(22-32-13-6-5-7-14-32)43(65)56(21-12-18-49-44(47)48)30-42(64)57(28-39(61)51-24-37(46)59)26-33-23-50-35-16-9-8-15-34(33)35/h5-9,13-16,23,36,50H,3-4,10-12,17-22,24-30,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H4,47,48,49)/t36-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410256
PNG
(CHEMBL190732)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-20-55(32(2)59)28-39(61)53-27-42(64)56(21-11-10-18-46)30-41(63)54-37(24-33-13-6-5-7-14-33)44(66)58(22-12-19-50-45(48)49)31-43(65)57(29-40(62)52-26-38(47)60)23-17-34-25-51-36-16-9-8-15-35(34)36/h5-9,13-16,25,37,51H,3-4,10-12,17-24,26-31,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H4,48,49,50)/t37-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410251
PNG
(CHEMBL2371835)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-17-34(54-29(2)59)41(63)53-27-39(61)55-35(19-10-11-20-46)43(65)57-37(23-30-14-6-5-7-15-30)44(66)58(22-13-12-21-50-45(48)49)28-40(62)56-36(42(64)52-26-38(47)60)24-31-25-51-33-18-9-8-16-32(31)33/h5-9,14-16,18,25,34-37,51H,3-4,10-13,17,19-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,64)(H,53,63)(H,54,59)(H,55,61)(H,56,62)(H,57,65)(H4,48,49,50)/t34-,35-,36?,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410243
PNG
(CHEMBL365794)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-36(54-31(2)59)43(65)53-27-41(63)56(21-11-10-19-46)29-40(62)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(28-39(61)52-26-38(47)60)23-18-33-25-51-35-17-9-8-15-34(33)35/h5-9,13-15,17,25,36-37,51H,3-4,10-12,16,18-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,61)(H,53,65)(H,54,59)(H,55,62)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410253
PNG
(CHEMBL371610)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-54(31(2)58)27-38(60)52-25-41(63)55(20-11-10-17-45)29-40(62)53-36(22-32-13-6-5-7-14-32)43(65)56(21-12-18-49-44(47)48)30-42(64)57(28-39(61)51-24-37(46)59)26-33-23-50-35-16-9-8-15-34(33)35/h5-9,13-16,23,36,50H,3-4,10-12,17-22,24-30,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H4,47,48,49)/t36-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410255
PNG
(CHEMBL2371828)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)51-25-38(60)54-35(17-10-11-19-45)43(65)57(26-30-13-6-5-7-14-30)28-40(62)53-34(18-12-20-49-44(47)48)42(64)55-36(41(63)52-24-37(46)59)22-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,62)(H,54,60)(H,55,64)(H4,47,48,49)/t34?,35-,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410255
PNG
(CHEMBL2371828)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)51-25-38(60)54-35(17-10-11-19-45)43(65)57(26-30-13-6-5-7-14-30)28-40(62)53-34(18-12-20-49-44(47)48)42(64)55-36(41(63)52-24-37(46)59)22-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,62)(H,54,60)(H,55,64)(H4,47,48,49)/t34?,35-,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410238
PNG
(CHEMBL370321)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-26-38(60)54-34(18-10-11-19-45)42(64)56-36(22-29-13-6-5-7-14-29)43(65)57(21-12-20-49-44(47)48)27-39(61)55-35(41(63)51-25-37(46)59)23-30-24-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,50H,3-4,10-12,16,18-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,63)(H,52,62)(H,53,58)(H,54,60)(H,55,61)(H,56,64)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410250
PNG
(CHEMBL2371833)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-55(30(2)58)27-38(60)51-26-41(63)56(20-11-10-17-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)57(21-12-18-49-44(47)48)29-40(62)53-35(42(64)52-25-37(46)59)23-32-24-50-34-16-9-8-15-33(32)34/h5-9,13-16,24,35-36,50H,3-4,10-12,17-23,25-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,62)(H,54,61)(H4,47,48,49)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410245
PNG
(CHEMBL191063)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-38(60)54-35(18-10-11-19-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)56(21-12-20-49-44(47)48)28-40(62)57(27-39(61)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,58)(H,54,60)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410246
PNG
(CHEMBL364711)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-39(61)53-27-42(64)57(22-11-10-19-46)30-41(63)54-37(24-32-13-6-5-7-14-32)43(65)55-36(17-12-20-50-45(48)49)44(66)58(29-40(62)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.31E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410244
PNG
(CHEMBL275999)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-39(61)52-25-38(60)53-35(17-10-11-18-45)42(64)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(28-40(62)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.94E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410237
PNG
(CHEMBL372237)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.94E+3n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410237
PNG
(CHEMBL372237)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410250
PNG
(CHEMBL2371833)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-55(30(2)58)27-38(60)51-26-41(63)56(20-11-10-17-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)57(21-12-18-49-44(47)48)29-40(62)53-35(42(64)52-25-37(46)59)23-32-24-50-34-16-9-8-15-33(32)34/h5-9,13-16,24,35-36,50H,3-4,10-12,17-23,25-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,62)(H,54,61)(H4,47,48,49)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.16E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410249
PNG
(CHEMBL373344)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-57(28(2)58)27-39(61)51-26-38(60)53-33(17-10-11-19-45)41(63)55-35(22-29-13-6-5-7-14-29)43(65)54-34(18-12-20-49-44(47)48)42(64)56-36(40(62)52-25-37(46)59)23-30-24-50-32-16-9-8-15-31(30)32/h5-9,13-16,24,33-36,50H,3-4,10-12,17-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,60)(H,54,65)(H,55,63)(H,56,64)(H4,47,48,49)/t33-,34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.5n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410259
PNG
(CHEMBL189991)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-35(53-30(2)58)42(64)52-25-40(62)55(20-11-10-18-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(27-38(60)51-24-37(46)59)26-32-23-50-34-17-9-8-15-33(32)34/h5-9,13-15,17,23,35-36,50H,3-4,10-12,16,18-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,58)(H,54,61)(H4,47,48,49)/t35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.16E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410255
PNG
(CHEMBL2371828)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)51-25-38(60)54-35(17-10-11-19-45)43(65)57(26-30-13-6-5-7-14-30)28-40(62)53-34(18-12-20-49-44(47)48)42(64)55-36(41(63)52-24-37(46)59)22-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,62)(H,54,60)(H,55,64)(H4,47,48,49)/t34?,35-,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410242
PNG
(CHEMBL2371832)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-26-40(62)56(20-11-10-18-45)27-38(60)55-36(22-30-13-6-5-7-14-30)43(65)57(21-12-19-49-44(47)48)28-39(61)54-35(42(64)51-25-37(46)59)23-31-24-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,24,34-36,50H,3-4,10-12,16,18-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,64)(H,52,63)(H,53,58)(H,54,61)(H,55,60)(H4,47,48,49)/t34-,35?,36?/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 501n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410236
PNG
(CHEMBL365913)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-32(53-27(2)58)39(61)52-26-38(60)54-33(18-10-11-20-45)41(63)56-35(22-28-13-6-5-7-14-28)43(65)55-34(19-12-21-49-44(47)48)42(64)57-36(40(62)51-25-37(46)59)23-29-24-50-31-17-9-8-15-30(29)31/h5-9,13-15,17,24,32-36,50H,3-4,10-12,16,18-23,25-26,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,58)(H,54,60)(H,55,65)(H,56,63)(H,57,64)(H4,47,48,49)/t32-,33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 7.90n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410243
PNG
(CHEMBL365794)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-36(54-31(2)59)43(65)53-27-41(63)56(21-11-10-19-46)29-40(62)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(28-39(61)52-26-38(47)60)23-18-33-25-51-35-17-9-8-15-34(33)35/h5-9,13-15,17,25,36-37,51H,3-4,10-12,16,18-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,61)(H,53,65)(H,54,59)(H,55,62)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410262
PNG
(CHEMBL190102)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)Cc1ccccc1
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-36(54-31(2)59)43(65)53-26-39(61)55-37(18-10-11-20-46)44(66)58(27-32-13-6-5-7-14-32)30-42(64)56(22-12-21-50-45(48)49)29-41(63)57(28-40(62)52-25-38(47)60)23-19-33-24-51-35-17-9-8-15-34(33)35/h5-9,13-15,17,24,36-37,51H,3-4,10-12,16,18-23,25-30,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,65)(H,54,59)(H,55,61)(H4,48,49,50)/t36-,37-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 7.94E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410248
PNG
(CHEMBL186970)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C43H63N11O8/c1-3-4-16-33(50-28(2)55)40(59)49-26-39(58)54(21-11-10-19-44)27-38(57)51-35(22-29-13-6-5-7-14-29)43(62)52-34(18-12-20-45)42(61)53-36(41(60)48-25-37(46)56)23-30-24-47-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,47H,3-4,10-12,16,18-23,25-27,44-45H2,1-2H3,(H2,46,56)(H,48,60)(H,49,59)(H,50,55)(H,51,57)(H,52,62)(H,53,61)/t33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 631n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410238
PNG
(CHEMBL370321)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-26-38(60)54-34(18-10-11-19-45)42(64)56-36(22-29-13-6-5-7-14-29)43(65)57(21-12-20-49-44(47)48)27-39(61)55-35(41(63)51-25-37(46)59)23-30-24-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,50H,3-4,10-12,16,18-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,63)(H,52,62)(H,53,58)(H,54,60)(H,55,61)(H,56,64)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 251n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410261
PNG
(CHEMBL191120)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-25-38(60)54-34(18-10-11-20-45)41(63)56-36(22-29-13-6-5-7-14-29)42(64)55-35(19-12-21-49-44(47)48)43(65)57(27-39(61)51-24-37(46)59)26-30-23-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,23,33-36,50H,3-4,10-12,16,18-22,24-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,58)(H,54,60)(H,55,64)(H,56,63)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 316n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410256
PNG
(CHEMBL190732)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-20-55(32(2)59)28-39(61)53-27-42(64)56(21-11-10-18-46)30-41(63)54-37(24-33-13-6-5-7-14-33)44(66)58(22-12-19-50-45(48)49)31-43(65)57(29-40(62)52-26-38(47)60)23-17-34-25-51-36-16-9-8-15-35(34)36/h5-9,13-16,25,37,51H,3-4,10-12,17-24,26-31,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H4,48,49,50)/t37-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.31E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410239
PNG
(CHEMBL190953)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-40(62)56(21-11-10-19-45)28-39(61)54-36(22-30-13-6-5-7-14-30)42(64)55-35(18-12-20-49-44(47)48)43(65)57(27-38(60)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,58)(H,54,61)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410251
PNG
(CHEMBL2371835)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-17-34(54-29(2)59)41(63)53-27-39(61)55-35(19-10-11-20-46)43(65)57-37(23-30-14-6-5-7-15-30)44(66)58(22-13-12-21-50-45(48)49)28-40(62)56-36(42(64)52-26-38(47)60)24-31-25-51-33-18-9-8-16-32(31)33/h5-9,14-16,18,25,34-37,51H,3-4,10-13,17,19-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,64)(H,53,63)(H,54,59)(H,55,61)(H,56,62)(H,57,65)(H4,48,49,50)/t34-,35-,36?,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 63n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410261
PNG
(CHEMBL191120)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-25-38(60)54-34(18-10-11-20-45)41(63)56-36(22-29-13-6-5-7-14-29)42(64)55-35(19-12-21-49-44(47)48)43(65)57(27-39(61)51-24-37(46)59)26-30-23-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,23,33-36,50H,3-4,10-12,16,18-22,24-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,58)(H,54,60)(H,55,64)(H,56,63)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 251n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410248
PNG
(CHEMBL186970)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C43H63N11O8/c1-3-4-16-33(50-28(2)55)40(59)49-26-39(58)54(21-11-10-19-44)27-38(57)51-35(22-29-13-6-5-7-14-29)43(62)52-34(18-12-20-45)42(61)53-36(41(60)48-25-37(46)56)23-30-24-47-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,47H,3-4,10-12,16,18-23,25-27,44-45H2,1-2H3,(H2,46,56)(H,48,60)(H,49,59)(H,50,55)(H,51,57)(H,52,62)(H,53,61)/t33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 316n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410239
PNG
(CHEMBL190953)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-40(62)56(21-11-10-19-45)28-39(61)54-36(22-30-13-6-5-7-14-30)42(64)55-35(18-12-20-49-44(47)48)43(65)57(27-38(60)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,58)(H,54,61)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.01E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410243
PNG
(CHEMBL365794)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-36(54-31(2)59)43(65)53-27-41(63)56(21-11-10-19-46)29-40(62)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(28-39(61)52-26-38(47)60)23-18-33-25-51-35-17-9-8-15-34(33)35/h5-9,13-15,17,25,36-37,51H,3-4,10-12,16,18-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,61)(H,53,65)(H,54,59)(H,55,62)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.98E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410244
PNG
(CHEMBL275999)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-39(61)52-25-38(60)53-35(17-10-11-18-45)42(64)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(28-40(62)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 501n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410237
PNG
(CHEMBL372237)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410263
PNG
(CHEMBL365262)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-22-57(30(2)59)28-40(62)53-27-39(61)54-35(17-10-11-20-46)42(64)56-37(24-31-13-6-5-7-14-31)43(65)55-36(18-12-21-50-45(48)49)44(66)58(29-41(63)52-26-38(47)60)23-19-32-25-51-34-16-9-8-15-33(32)34/h5-9,13-16,25,35-37,51H,3-4,10-12,17-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H,56,64)(H4,48,49,50)/t35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.16E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410236
PNG
(CHEMBL365913)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-32(53-27(2)58)39(61)52-26-38(60)54-33(18-10-11-20-45)41(63)56-35(22-28-13-6-5-7-14-28)43(65)55-34(19-12-21-49-44(47)48)42(64)57-36(40(62)51-25-37(46)59)23-29-24-50-31-17-9-8-15-30(29)31/h5-9,13-15,17,24,32-36,50H,3-4,10-12,16,18-23,25-26,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,58)(H,54,60)(H,55,65)(H,56,63)(H,57,64)(H4,47,48,49)/t32-,33-,34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 0.501n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410261
PNG
(CHEMBL191120)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-25-38(60)54-34(18-10-11-20-45)41(63)56-36(22-29-13-6-5-7-14-29)42(64)55-35(19-12-21-49-44(47)48)43(65)57(27-39(61)51-24-37(46)59)26-30-23-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,23,33-36,50H,3-4,10-12,16,18-22,24-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,58)(H,54,60)(H,55,64)(H,56,63)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 158n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410254
PNG
(CHEMBL190203)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 631n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410249
PNG
(CHEMBL373344)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-57(28(2)58)27-39(61)51-26-38(60)53-33(17-10-11-19-45)41(63)55-35(22-29-13-6-5-7-14-29)43(65)54-34(18-12-20-49-44(47)48)42(64)56-36(40(62)52-25-37(46)59)23-30-24-50-32-16-9-8-15-31(30)32/h5-9,13-16,24,33-36,50H,3-4,10-12,17-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,60)(H,54,65)(H,55,63)(H,56,64)(H4,47,48,49)/t33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 794n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410242
PNG
(CHEMBL2371832)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-26-40(62)56(20-11-10-18-45)27-38(60)55-36(22-30-13-6-5-7-14-30)43(65)57(21-12-19-49-44(47)48)28-39(61)54-35(42(64)51-25-37(46)59)23-31-24-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,24,34-36,50H,3-4,10-12,16,18-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,64)(H,52,63)(H,53,58)(H,54,61)(H,55,60)(H4,47,48,49)/t34-,35?,36?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410264
PNG
(CHEMBL2371829)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-39(61)51-26-38(60)53-34(17-10-11-18-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)57(21-12-19-49-44(47)48)28-40(62)54-35(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,60)(H,54,62)(H,55,64)(H4,47,48,49)/t34-,35?,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 794n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410259
PNG
(CHEMBL189991)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-35(53-30(2)58)42(64)52-25-40(62)55(20-11-10-18-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(27-38(60)51-24-37(46)59)26-32-23-50-34-17-9-8-15-33(32)34/h5-9,13-15,17,23,35-36,50H,3-4,10-12,16,18-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,58)(H,54,61)(H4,47,48,49)/t35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410251
PNG
(CHEMBL2371835)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-17-34(54-29(2)59)41(63)53-27-39(61)55-35(19-10-11-20-46)43(65)57-37(23-30-14-6-5-7-15-30)44(66)58(22-13-12-21-50-45(48)49)28-40(62)56-36(42(64)52-26-38(47)60)24-31-25-51-33-18-9-8-16-32(31)33/h5-9,14-16,18,25,34-37,51H,3-4,10-13,17,19-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,64)(H,53,63)(H,54,59)(H,55,61)(H,56,62)(H,57,65)(H4,48,49,50)/t34-,35-,36?,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 251n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410237
PNG
(CHEMBL372237)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410240
PNG
(CHEMBL2371827)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-25-38(60)55-35(18-10-11-20-45)43(65)57(26-29-13-6-5-7-14-29)27-39(61)54-34(19-12-21-49-44(47)48)42(64)56-36(41(63)51-24-37(46)59)22-30-23-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,23,33-36,50H,3-4,10-12,16,18-22,24-27,45H2,1-2H3,(H2,46,59)(H,51,63)(H,52,62)(H,53,58)(H,54,61)(H,55,60)(H,56,64)(H4,47,48,49)/t33-,34?,35-,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.26E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410257
PNG
(CHEMBL188738)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-40(62)53-27-39(61)54-36(17-10-11-19-46)43(65)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(29-41(63)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 316n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410254
PNG
(CHEMBL190203)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 794n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410252
PNG
(CHEMBL190551)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-35(54-30(2)59)42(64)53-27-39(61)55-36(18-10-11-20-46)43(65)56-37(24-31-13-6-5-7-14-31)44(66)58(22-12-21-50-45(48)49)29-41(63)57(28-40(62)52-26-38(47)60)23-19-32-25-51-34-17-9-8-15-33(32)34/h5-9,13-15,17,25,35-37,51H,3-4,10-12,16,18-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,64)(H,54,59)(H,55,61)(H,56,65)(H4,48,49,50)/t35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 158n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410259
PNG
(CHEMBL189991)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-35(53-30(2)58)42(64)52-25-40(62)55(20-11-10-18-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)56(21-12-19-49-44(47)48)29-41(63)57(27-38(60)51-24-37(46)59)26-32-23-50-34-17-9-8-15-33(32)34/h5-9,13-15,17,23,35-36,50H,3-4,10-12,16,18-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,58)(H,54,61)(H4,47,48,49)/t35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.31E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410263
PNG
(CHEMBL365262)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-22-57(30(2)59)28-40(62)53-27-39(61)54-35(17-10-11-20-46)42(64)56-37(24-31-13-6-5-7-14-31)43(65)55-36(18-12-21-50-45(48)49)44(66)58(29-41(63)52-26-38(47)60)23-19-32-25-51-34-16-9-8-15-33(32)34/h5-9,13-16,25,35-37,51H,3-4,10-12,17-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H,56,64)(H4,48,49,50)/t35-,36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 316n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410246
PNG
(CHEMBL364711)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-39(61)53-27-42(64)57(22-11-10-19-46)30-41(63)54-37(24-32-13-6-5-7-14-32)43(65)55-36(17-12-20-50-45(48)49)44(66)58(29-40(62)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.31E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410247
PNG
(CHEMBL190080)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C46H69N13O8/c1-3-4-17-36(55-31(2)60)43(65)54-28-40(62)56-37(19-10-11-21-47)44(66)57-38(25-32-14-6-5-7-15-32)45(67)59(23-13-12-22-51-46(49)50)30-42(64)58(29-41(63)53-27-39(48)61)24-20-33-26-52-35-18-9-8-16-34(33)35/h5-9,14-16,18,26,36-38,52H,3-4,10-13,17,19-25,27-30,47H2,1-2H3,(H2,48,61)(H,53,63)(H,54,65)(H,55,60)(H,56,62)(H,57,66)(H4,49,50,51)/t36-,37-,38+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 251n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410248
PNG
(CHEMBL186970)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C43H63N11O8/c1-3-4-16-33(50-28(2)55)40(59)49-26-39(58)54(21-11-10-19-44)27-38(57)51-35(22-29-13-6-5-7-14-29)43(62)52-34(18-12-20-45)42(61)53-36(41(60)48-25-37(46)56)23-30-24-47-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,47H,3-4,10-12,16,18-23,25-27,44-45H2,1-2H3,(H2,46,56)(H,48,60)(H,49,59)(H,50,55)(H,51,57)(H,52,62)(H,53,61)/t33-,34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 20n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410245
PNG
(CHEMBL191063)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-38(60)54-35(18-10-11-19-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)56(21-12-20-49-44(47)48)28-40(62)57(27-39(61)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,58)(H,54,60)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410252
PNG
(CHEMBL190551)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-35(54-30(2)59)42(64)53-27-39(61)55-36(18-10-11-20-46)43(65)56-37(24-31-13-6-5-7-14-31)44(66)58(22-12-21-50-45(48)49)29-41(63)57(28-40(62)52-26-38(47)60)23-19-32-25-51-34-17-9-8-15-33(32)34/h5-9,13-15,17,25,35-37,51H,3-4,10-12,16,18-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,64)(H,54,59)(H,55,61)(H,56,65)(H4,48,49,50)/t35-,36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410250
PNG
(CHEMBL2371833)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-55(30(2)58)27-38(60)51-26-41(63)56(20-11-10-17-45)28-39(61)54-36(22-31-13-6-5-7-14-31)43(65)57(21-12-18-49-44(47)48)29-40(62)53-35(42(64)52-25-37(46)59)23-32-24-50-34-16-9-8-15-33(32)34/h5-9,13-16,24,35-36,50H,3-4,10-12,17-23,25-29,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,64)(H,53,62)(H,54,61)(H4,47,48,49)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.31E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410253
PNG
(CHEMBL371610)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-19-54(31(2)58)27-38(60)52-25-41(63)55(20-11-10-17-45)29-40(62)53-36(22-32-13-6-5-7-14-32)43(65)56(21-12-18-49-44(47)48)30-42(64)57(28-39(61)51-24-37(46)59)26-33-23-50-35-16-9-8-15-34(33)35/h5-9,13-16,23,36,50H,3-4,10-12,17-22,24-30,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H4,47,48,49)/t36-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.01E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410258
PNG
(CHEMBL2371823)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N(CC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)Cc1ccccc1
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-39(61)56(21-11-10-19-45)28-40(62)57(26-30-13-6-5-7-14-30)27-38(60)54-35(18-12-20-49-44(47)48)43(65)55-36(42(64)51-24-37(46)59)22-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,64)(H,52,63)(H,53,58)(H,54,60)(H,55,65)(H4,47,48,49)/t34-,35?,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410247
PNG
(CHEMBL190080)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C46H69N13O8/c1-3-4-17-36(55-31(2)60)43(65)54-28-40(62)56-37(19-10-11-21-47)44(66)57-38(25-32-14-6-5-7-15-32)45(67)59(23-13-12-22-51-46(49)50)30-42(64)58(29-41(63)53-27-39(48)61)24-20-33-26-52-35-18-9-8-16-34(33)35/h5-9,14-16,18,26,36-38,52H,3-4,10-13,17,19-25,27-30,47H2,1-2H3,(H2,48,61)(H,53,63)(H,54,65)(H,55,60)(H,56,62)(H,57,66)(H4,49,50,51)/t36-,37-,38+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 501n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410241
PNG
(CHEMBL188459)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-38(60)51-26-40(62)57(21-11-10-18-45)28-39(61)53-35(22-30-13-6-5-7-14-30)43(65)54-34(17-12-19-49-44(47)48)42(64)55-36(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,61)(H,54,65)(H,55,64)(H4,47,48,49)/t34-,35+,36-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 63n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410238
PNG
(CHEMBL370321)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-26-38(60)54-34(18-10-11-19-45)42(64)56-36(22-29-13-6-5-7-14-29)43(65)57(21-12-20-49-44(47)48)27-39(61)55-35(41(63)51-25-37(46)59)23-30-24-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,50H,3-4,10-12,16,18-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,63)(H,52,62)(H,53,58)(H,54,60)(H,55,61)(H,56,64)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 631n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410237
PNG
(CHEMBL372237)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-34(54-29(2)59)41(63)53-27-39(61)55-35(18-10-11-21-46)42(64)57-37(24-30-13-6-5-7-14-30)43(65)56-36(19-12-22-50-45(48)49)44(66)58(28-40(62)52-26-38(47)60)23-20-31-25-51-33-17-9-8-15-32(31)33/h5-9,13-15,17,25,34-37,51H,3-4,10-12,16,18-24,26-28,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,63)(H,54,59)(H,55,61)(H,56,65)(H,57,64)(H4,48,49,50)/t34-,35-,36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 316n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410247
PNG
(CHEMBL190080)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C46H69N13O8/c1-3-4-17-36(55-31(2)60)43(65)54-28-40(62)56-37(19-10-11-21-47)44(66)57-38(25-32-14-6-5-7-15-32)45(67)59(23-13-12-22-51-46(49)50)30-42(64)58(29-41(63)53-27-39(48)61)24-20-33-26-52-35-18-9-8-16-34(33)35/h5-9,14-16,18,26,36-38,52H,3-4,10-13,17,19-25,27-30,47H2,1-2H3,(H2,48,61)(H,53,63)(H,54,65)(H,55,60)(H,56,62)(H,57,66)(H4,49,50,51)/t36-,37-,38+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410249
PNG
(CHEMBL373344)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-57(28(2)58)27-39(61)51-26-38(60)53-33(17-10-11-19-45)41(63)55-35(22-29-13-6-5-7-14-29)43(65)54-34(18-12-20-49-44(47)48)42(64)56-36(40(62)52-25-37(46)59)23-30-24-50-32-16-9-8-15-31(30)32/h5-9,13-16,24,33-36,50H,3-4,10-12,17-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,62)(H,53,60)(H,54,65)(H,55,63)(H,56,64)(H4,47,48,49)/t33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 25n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410241
PNG
(CHEMBL188459)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-38(60)51-26-40(62)57(21-11-10-18-45)28-39(61)53-35(22-30-13-6-5-7-14-30)43(65)54-34(17-12-19-49-44(47)48)42(64)55-36(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,61)(H,54,65)(H,55,64)(H4,47,48,49)/t34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410245
PNG
(CHEMBL191063)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-38(60)54-35(18-10-11-19-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)56(21-12-20-49-44(47)48)28-40(62)57(27-39(61)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,58)(H,54,60)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 631n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410256
PNG
(CHEMBL190732)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-20-55(32(2)59)28-39(61)53-27-42(64)56(21-11-10-18-46)30-41(63)54-37(24-33-13-6-5-7-14-33)44(66)58(22-12-19-50-45(48)49)31-43(65)57(29-40(62)52-26-38(47)60)23-17-34-25-51-36-16-9-8-15-35(34)36/h5-9,13-16,25,37,51H,3-4,10-12,17-24,26-31,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,61)(H,54,63)(H4,48,49,50)/t37-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 794n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410257
PNG
(CHEMBL188738)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-40(62)53-27-39(61)54-36(17-10-11-19-46)43(65)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(29-41(63)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 158n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410254
PNG
(CHEMBL190203)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-21-56(29(2)58)27-39(61)52-25-38(60)53-34(17-10-11-19-45)41(63)55-36(22-30-13-6-5-7-14-30)42(64)54-35(18-12-20-49-44(47)48)43(65)57(28-40(62)51-24-37(46)59)26-31-23-50-33-16-9-8-15-32(31)33/h5-9,13-16,23,34-36,50H,3-4,10-12,17-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,60)(H,54,64)(H,55,63)(H4,47,48,49)/t34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.98E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410238
PNG
(CHEMBL370321)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-33(53-28(2)58)40(62)52-26-38(60)54-34(18-10-11-19-45)42(64)56-36(22-29-13-6-5-7-14-29)43(65)57(21-12-20-49-44(47)48)27-39(61)55-35(41(63)51-25-37(46)59)23-30-24-50-32-17-9-8-15-31(30)32/h5-9,13-15,17,24,33-36,50H,3-4,10-12,16,18-23,25-27,45H2,1-2H3,(H2,46,59)(H,51,63)(H,52,62)(H,53,58)(H,54,60)(H,55,61)(H,56,64)(H4,47,48,49)/t33-,34-,35-,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.98E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410239
PNG
(CHEMBL190953)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-40(62)56(21-11-10-19-45)28-39(61)54-36(22-30-13-6-5-7-14-30)42(64)55-35(18-12-20-49-44(47)48)43(65)57(27-38(60)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,58)(H,54,61)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.26E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410260
PNG
(CHEMBL190427)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-55(30(2)58)27-38(60)52-25-41(63)56(21-11-10-18-45)29-40(62)53-36(22-31-13-6-5-7-14-31)42(64)54-35(17-12-19-49-44(47)48)43(65)57(28-39(61)51-24-37(46)59)26-32-23-50-34-16-9-8-15-33(32)34/h5-9,13-16,23,35-36,50H,3-4,10-12,17-22,24-29,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,60)(H,53,62)(H,54,64)(H4,47,48,49)/t35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.98E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410257
PNG
(CHEMBL188738)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-21-56(31(2)59)28-40(62)53-27-39(61)54-36(17-10-11-19-46)43(65)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(29-41(63)52-26-38(47)60)23-18-33-25-51-35-16-9-8-15-34(33)35/h5-9,13-16,25,36-37,51H,3-4,10-12,17-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,63)(H,53,62)(H,54,61)(H,55,65)(H4,48,49,50)/t36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410264
PNG
(CHEMBL2371829)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-39(61)51-26-38(60)53-34(17-10-11-18-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)57(21-12-19-49-44(47)48)28-40(62)54-35(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,60)(H,54,62)(H,55,64)(H4,47,48,49)/t34-,35?,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 6.31E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410265
PNG
(CHEMBL190834)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-35(54-30(2)59)42(64)53-27-41(63)57(22-11-10-20-46)29-40(62)55-37(24-31-13-6-5-7-14-31)43(65)56-36(18-12-21-50-45(48)49)44(66)58(28-39(61)52-26-38(47)60)23-19-32-25-51-34-17-9-8-15-33(32)34/h5-9,13-15,17,25,35-37,51H,3-4,10-12,16,18-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,61)(H,53,64)(H,54,59)(H,55,62)(H,56,65)(H4,48,49,50)/t35-,36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410252
PNG
(CHEMBL190551)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-35(54-30(2)59)42(64)53-27-39(61)55-36(18-10-11-20-46)43(65)56-37(24-31-13-6-5-7-14-31)44(66)58(22-12-21-50-45(48)49)29-41(63)57(28-40(62)52-26-38(47)60)23-19-32-25-51-34-17-9-8-15-33(32)34/h5-9,13-15,17,25,35-37,51H,3-4,10-12,16,18-24,26-29,46H2,1-2H3,(H2,47,60)(H,52,62)(H,53,64)(H,54,59)(H,55,61)(H,56,65)(H4,48,49,50)/t35-,36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 79n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410236
PNG
(CHEMBL365913)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-32(53-27(2)58)39(61)52-26-38(60)54-33(18-10-11-20-45)41(63)56-35(22-28-13-6-5-7-14-28)43(65)55-34(19-12-21-49-44(47)48)42(64)57-36(40(62)51-25-37(46)59)23-29-24-50-31-17-9-8-15-30(29)31/h5-9,13-15,17,24,32-36,50H,3-4,10-12,16,18-23,25-26,45H2,1-2H3,(H2,46,59)(H,51,62)(H,52,61)(H,53,58)(H,54,60)(H,55,65)(H,56,63)(H,57,64)(H4,47,48,49)/t32-,33-,34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 32n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50410264
PNG
(CHEMBL2371829)
Show SMILES CCCCN(CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCN=C(N)N)CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-39(61)51-26-38(60)53-34(17-10-11-18-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)57(21-12-19-49-44(47)48)28-40(62)54-35(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,60)(H,54,62)(H,55,64)(H4,47,48,49)/t34-,35?,36+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.01E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against human melanocortin receptor-3 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50410241
PNG
(CHEMBL188459)
Show SMILES CCCCN(CC(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O)C(C)=O
Show InChI InChI=1S/C44H65N13O8/c1-3-4-20-56(29(2)58)27-38(60)51-26-40(62)57(21-11-10-18-45)28-39(61)53-35(22-30-13-6-5-7-14-30)43(65)54-34(17-12-19-49-44(47)48)42(64)55-36(41(63)52-25-37(46)59)23-31-24-50-33-16-9-8-15-32(31)33/h5-9,13-16,24,34-36,50H,3-4,10-12,17-23,25-28,45H2,1-2H3,(H2,46,59)(H,51,60)(H,52,63)(H,53,61)(H,54,65)(H,55,64)(H4,47,48,49)/t34-,35+,36-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 7.94E+3n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Effective concentration against mouse melanocortin receptor-5 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410245
PNG
(CHEMBL191063)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CC(=O)NCC(N)=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C44H65N13O8/c1-3-4-16-34(53-29(2)58)41(63)52-25-38(60)54-35(18-10-11-19-45)42(64)55-36(22-30-13-6-5-7-14-30)43(65)56(21-12-20-49-44(47)48)28-40(62)57(27-39(61)51-24-37(46)59)26-31-23-50-33-17-9-8-15-32(31)33/h5-9,13-15,17,23,34-36,50H,3-4,10-12,16,18-22,24-28,45H2,1-2H3,(H2,46,59)(H,51,61)(H,52,63)(H,53,58)(H,54,60)(H,55,64)(H4,47,48,49)/t34-,35-,36+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 158n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50410243
PNG
(CHEMBL365794)
Show SMILES CCCC[C@H](NC(C)=O)C(=O)NCC(=O)N(CCCCN)CC(=O)N[C@H](Cc1ccccc1)C(=O)N(CCCNC(N)=N)CC(=O)N(CCc1c[nH]c2ccccc12)CC(=O)NCC(N)=O
Show InChI InChI=1S/C45H67N13O8/c1-3-4-16-36(54-31(2)59)43(65)53-27-41(63)56(21-11-10-19-46)29-40(62)55-37(24-32-13-6-5-7-14-32)44(66)58(22-12-20-50-45(48)49)30-42(64)57(28-39(61)52-26-38(47)60)23-18-33-25-51-35-17-9-8-15-34(33)35/h5-9,13-15,17,25,36-37,51H,3-4,10-12,16,18-24,26-30,46H2,1-2H3,(H2,47,60)(H,52,61)(H,53,65)(H,54,59)(H,55,62)(H4,48,49,50)/t36-,37+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 398n/an/an/an/a



Utrecht University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human melanocortin receptor-4 expressed in 293 HEK cells


J Med Chem 48: 4224-30 (2005)


Article DOI: 10.1021/jm0490033
BindingDB Entry DOI: 10.7270/Q2QV3NQ5
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%