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Found 5 Enz. Inhib. hit(s) with all data for entry = 50038612
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50008923((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50269441(CHEMBL465592 | Isorauhimbinic acid)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50017712((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Kobe Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant DNA topoisomerase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed