Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calpain1/2 (Homo sapiens (Human)) | BDBM16510![]() ((2S,3S)-3-[[(1S)-1-(isoamylcarbamoyl)-3-methyl-but...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406632![]() (CHEMBL302897) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406636![]() (CHEMBL294046) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406637![]() (CHEMBL61010) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406637![]() (CHEMBL61010) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406635![]() (CHEMBL63494) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406632![]() (CHEMBL302897) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406628![]() (CHEMBL418130) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406635![]() (CHEMBL63494) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406634![]() (CHEMBL303315) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406634![]() (CHEMBL303315) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406638![]() (CHEMBL64174) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406636![]() (CHEMBL294046) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50052693![]() ((2S,3S)-3-[(S)-3-Methyl-1-(3-methyl-butylcarbamoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406630![]() (CHEMBL60482) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50052693![]() ((2S,3S)-3-[(S)-3-Methyl-1-(3-methyl-butylcarbamoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406629![]() (CHEMBL302443) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406630![]() (CHEMBL60482) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406633![]() (CHEMBL64647) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain1/2 (Homo sapiens (Human)) | BDBM50406631![]() (CHEMBL62988) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Health Science Center Curated by ChEMBL | Assay Description The ability of compound to inhibit calpain in a preparation of lysed platelets was measured with a caseinolytic assay(assay 1) | J Med Chem 35: 2048-54 (1992) Article DOI: 10.1021/jm00089a015 BindingDB Entry DOI: 10.7270/Q27M094H | |||||||||||
More data for this Ligand-Target Pair |