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Found 162 Enz. Inhib. hit(s) with all data for entry = 50016551
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170537(6-Phenoxymethyl-pyridine-2-carboxylic acid (3-hydr...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170540(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170473(6-Phenoxymethyl-pyridine-2-carboxylic acid (4-hydr...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170475(6-Phenoxymethyl-pyridine-2-carboxylic acid (6-hydr...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170491(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170500(10-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-...)
Affinity DataIC50:  74nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170491(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  74nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  87nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170482(9-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-p...)
Affinity DataIC50:  96nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170526(2-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-be...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170487(CHEMBL188333 | Quinoline-2-carboxylic acid (4-hydr...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170502(6-Phenoxymethyl-pyridine-2-carboxylic acid (4-hydr...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170492(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170514(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  230nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170547(({[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-py...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170529(3-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-p...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170492(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170550(4-(4-Chloro-phenoxy)-N-(4-hydroxycarbamoylmethyl-t...)
Affinity DataIC50:  320nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170561(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  350nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170554(1-Phenyl-1,4-dihydro-quinoline-4-carboxylic acid (...)
Affinity DataIC50:  380nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170501(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  390nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170511(CHEMBL366212 | N-(4-Hydroxycarbamoylmethyl-thiazol...)
Affinity DataIC50:  430nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170515((S)-2-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethy...)
Affinity DataIC50:  460nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170501(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170479(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  520nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170531(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  620nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170539(9-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-be...)
Affinity DataIC50:  630nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170466(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  630nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170558(2-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-be...)
Affinity DataIC50:  650nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170479(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  670nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170512(2-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-be...)
Affinity DataIC50:  680nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170564(6-Phenoxymethyl-pyridine-2-carboxylic acid (5-hydr...)
Affinity DataIC50:  770nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170554(1-Phenyl-1,4-dihydro-quinoline-4-carboxylic acid (...)
Affinity DataIC50:  790nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170465(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  830nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170466(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  890nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170524(CHEMBL363889 | [3-(4-Acetyl-2-ethyl-5-hydroxy-phen...)
Affinity DataIC50:  920nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170502(6-Phenoxymethyl-pyridine-2-carboxylic acid (4-hydr...)
Affinity DataIC50:  920nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170552(CHEMBL365147 | Naphthalene-1-carboxylic acid (4-hy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170509((R)-2-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethy...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170552(CHEMBL365147 | Naphthalene-1-carboxylic acid (4-hy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170540(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170528(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170535(2-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-p...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170517(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50170465(6-Phenoxymethyl-pyridine-2-carboxylic acid [4-(1-h...)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170523(3-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-p...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170522(CHEMBL188233 | N-{6-[(hydroxyamino)carbonyl]pyridi...)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170506(9-{[6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-p...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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