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PubMed code 16087332

Compile data set for download or QSAR
Found 33 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9727
PNG
(2-methylpropyl N-[(S)-{[(1S)-1-({1-[({[(S)-carbamo...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@H](C(N)=O)c1ccccc1
Show InChI InChI=1S/C35H54N6O8/c1-6-13-25(30(43)34(47)37-19-27(42)40-28(31(36)44)23-14-9-7-10-15-23)38-32(45)26(18-21(2)3)39-33(46)29(24-16-11-8-12-17-24)41-35(48)49-20-22(4)5/h7,9-10,14-15,21-22,24-26,28-29H,6,8,11-13,16-20H2,1-5H3,(H2,36,44)(H,37,47)(H,38,45)(H,39,46)(H,40,42)(H,41,48)/t25?,26-,28-,29-/m0/s1
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66n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9731
PNG
((2S)-2-(2-{3-[(2S)-2-[(2S)-2-{[(tert-butoxy)carbon...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@H](C(O)=O)c1ccccc1
Show InChI InChI=1S/C35H53N5O9/c1-7-14-24(29(42)32(45)36-20-26(41)39-28(33(46)47)23-17-12-9-13-18-23)37-30(43)25(19-21(2)3)38-31(44)27(22-15-10-8-11-16-22)40-34(48)49-35(4,5)6/h9,12-13,17-18,21-22,24-25,27-28H,7-8,10-11,14-16,19-20H2,1-6H3,(H,36,45)(H,37,43)(H,38,44)(H,39,41)(H,40,48)(H,46,47)/t24?,25-,27-,28-/m0/s1
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98n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9729
PNG
((2S)-2-(2-{3-[(2S)-2-[(2S)-2-cyclohexyl-2-{[(2-met...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@H](C(O)=O)c1ccccc1
Show InChI InChI=1S/C35H53N5O9/c1-6-13-25(30(42)33(45)36-19-27(41)39-29(34(46)47)24-16-11-8-12-17-24)37-31(43)26(18-21(2)3)38-32(44)28(23-14-9-7-10-15-23)40-35(48)49-20-22(4)5/h8,11-12,16-17,21-23,25-26,28-29H,6-7,9-10,13-15,18-20H2,1-5H3,(H,36,45)(H,37,43)(H,38,44)(H,39,41)(H,40,48)(H,46,47)/t25?,26-,28-,29-/m0/s1
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120n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9725
PNG
(2-methylpropyl N-[(S)-{[(1S)-1-({1-[({[(1S)-1-carb...)
Show SMILES CCCC[C@H](NC(=O)CNC(=O)C(=O)C(CCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(N)=O
Show InChI InChI=1S/C33H58N6O8/c1-7-9-16-24(29(34)42)36-26(40)18-35-32(45)28(41)23(13-8-2)37-30(43)25(17-20(3)4)38-31(44)27(22-14-11-10-12-15-22)39-33(46)47-19-21(5)6/h20-25,27H,7-19H2,1-6H3,(H2,34,42)(H,35,45)(H,36,40)(H,37,43)(H,38,44)(H,39,46)/t23?,24-,25-,27-/m0/s1
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280n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9726
PNG
((2S)-2-(2-{3-[(2S)-2-[(2S)-2-cyclohexyl-2-{[(2-met...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@@H](C1CCCC1)C(O)=O
Show InChI InChI=1S/C34H57N5O9/c1-6-12-24(29(41)32(44)35-18-26(40)38-28(33(45)46)23-15-10-11-16-23)36-30(42)25(17-20(2)3)37-31(43)27(22-13-8-7-9-14-22)39-34(47)48-19-21(4)5/h20-25,27-28H,6-19H2,1-5H3,(H,35,44)(H,36,42)(H,37,43)(H,38,40)(H,39,47)(H,45,46)/t24?,25-,27-,28-/m0/s1
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330n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9719
PNG
(2-methylpropyl N-[(1S)-2-[(2S)-2-({1-[({[(S)-carba...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@H](C(N)=O)c1ccccc1
Show InChI InChI=1S/C34H50N6O8/c1-4-12-24(29(42)32(45)36-19-26(41)38-27(30(35)43)22-13-7-5-8-14-22)37-31(44)25-17-11-18-40(25)33(46)28(23-15-9-6-10-16-23)39-34(47)48-20-21(2)3/h5,7-8,13-14,21,23-25,27-28H,4,6,9-12,15-20H2,1-3H3,(H2,35,43)(H,36,45)(H,37,44)(H,38,41)(H,39,47)/t24?,25-,27-,28-/m0/s1
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360n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9720
PNG
(P3-capped alpha-ketoamide inhibitor 35)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@@H](COC(C)(C)C)C(N)=O
Show InChI InChI=1S/C34H60N6O9/c1-9-13-23(28(42)32(46)36-17-26(41)37-25(29(35)43)19-49-34(6,7)8)38-30(44)24(16-20(2)3)39-31(45)27(22-14-11-10-12-15-22)40-33(47)48-18-21(4)5/h20-25,27H,9-19H2,1-8H3,(H2,35,43)(H,36,46)(H,37,41)(H,38,44)(H,39,45)(H,40,47)/t23?,24-,25-,27-/m0/s1
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460n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9730
PNG
(P3-capped alpha-ketoamide inhibitor 46 | benzyl (2...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@H](C(=O)OCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C42H59N5O9/c1-7-17-31(44-37(50)32(24-27(2)3)45-38(51)34(29-20-13-9-14-21-29)47-41(54)56-42(4,5)6)36(49)39(52)43-25-33(48)46-35(30-22-15-10-16-23-30)40(53)55-26-28-18-11-8-12-19-28/h8,10-12,15-16,18-19,22-23,27,29,31-32,34-35H,7,9,13-14,17,20-21,24-26H2,1-6H3,(H,43,52)(H,44,50)(H,45,51)(H,46,48)(H,47,54)/t31?,32-,34-,35-/m0/s1
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600n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9728
PNG
(P3-capped alpha-ketoamide inhibitor 44 | tert-buty...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1
Show InChI InChI=1S/C39H61N5O9/c1-9-16-28(33(46)36(49)40-22-30(45)43-32(27-19-14-11-15-20-27)37(50)53-39(6,7)8)41-34(47)29(21-24(2)3)42-35(48)31(26-17-12-10-13-18-26)44-38(51)52-23-25(4)5/h11,14-15,19-20,24-26,28-29,31-32H,9-10,12-13,16-18,21-23H2,1-8H3,(H,40,49)(H,41,47)(H,42,48)(H,43,45)(H,44,51)/t28?,29-,31-,32-/m0/s1
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650n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9718
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(S)-carba...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@H](C(N)=O)c1ccccc1
Show InChI InChI=1S/C31H46N6O8/c1-6-11-21(26(39)29(42)33-16-23(38)35-25(27(32)40)20-12-8-7-9-13-20)34-28(41)22-14-10-15-37(22)30(43)24(19(4)5)36-31(44)45-17-18(2)3/h7-9,12-13,18-19,21-22,24-25H,6,10-11,14-17H2,1-5H3,(H2,32,40)(H,33,42)(H,34,41)(H,35,38)(H,36,44)/t21?,22-,24-,25-/m0/s1
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2.10E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9712
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(S)-carba...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](C1CCCCC1)C(N)=O
Show InChI InChI=1S/C31H52N6O8/c1-6-11-21(26(39)29(42)33-16-23(38)35-25(27(32)40)20-12-8-7-9-13-20)34-28(41)22-14-10-15-37(22)30(43)24(19(4)5)36-31(44)45-17-18(2)3/h18-22,24-25H,6-17H2,1-5H3,(H2,32,40)(H,33,42)(H,34,41)(H,35,38)(H,36,44)/t21?,22-,24-,25-/m0/s1
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2.60E+3 -32.4n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9724
PNG
(2-methylpropyl N-[(S)-{[(1S)-1-({1-[({[(1S)-1-carb...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(N)=O
Show InChI InChI=1S/C32H56N6O8/c1-8-12-22(27(40)31(44)34-16-24(39)37-25(20(6)7)28(33)41)35-29(42)23(15-18(2)3)36-30(43)26(21-13-10-9-11-14-21)38-32(45)46-17-19(4)5/h18-23,25-26H,8-17H2,1-7H3,(H2,33,41)(H,34,44)(H,35,42)(H,36,43)(H,37,39)(H,38,45)/t22?,23-,25-,26-/m0/s1
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2.60E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9722
PNG
((2S)-2-{1-[(tert-butoxy)carbonyl]piperidin-4-yl}-2...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@@H](C1CCN(CC1)C(=O)OC(C)(C)C)C(O)=O
Show InChI InChI=1S/C39H66N6O11/c1-9-13-27(32(47)35(50)40-21-29(46)43-31(36(51)52)26-16-18-45(19-17-26)38(54)56-39(6,7)8)41-33(48)28(20-23(2)3)42-34(49)30(25-14-11-10-12-15-25)44-37(53)55-22-24(4)5/h23-28,30-31H,9-22H2,1-8H3,(H,40,50)(H,41,48)(H,42,49)(H,43,46)(H,44,53)(H,51,52)/t27?,28-,30-,31-/m0/s1
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3.30E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9710
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-2-(b...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](COCc1ccccc1)C(N)=O
Show InChI InChI=1S/C33H50N6O9/c1-6-11-23(28(41)31(44)35-16-26(40)36-24(29(34)42)19-47-18-22-12-8-7-9-13-22)37-30(43)25-14-10-15-39(25)32(45)27(21(4)5)38-33(46)48-17-20(2)3/h7-9,12-13,20-21,23-25,27H,6,10-11,14-19H2,1-5H3,(H2,34,42)(H,35,44)(H,36,40)(H,37,43)(H,38,46)/t23?,24-,25-,27-/m0/s1
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3.50E+3 -31.7n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9723
PNG
((2S)-2-(2-{3-[(2S)-2-[(2S)-2-cyclohexyl-2-{[(2-met...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@@H](C1CCNCC1)C(O)=O
Show InChI InChI=1S/C34H58N6O9/c1-6-10-24(29(42)32(45)36-18-26(41)39-28(33(46)47)23-13-15-35-16-14-23)37-30(43)25(17-20(2)3)38-31(44)27(22-11-8-7-9-12-22)40-34(48)49-19-21(4)5/h20-25,27-28,35H,6-19H2,1-5H3,(H,36,45)(H,37,43)(H,38,44)(H,39,41)(H,40,48)(H,46,47)/t24?,25-,27-,28-/m0/s1
PDB
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DrugBank
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UniChem

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Article
PubMed
6.40E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9715
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-1-ca...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CCc1ccccc1)C(N)=O
Show InChI InChI=1S/C33H50N6O8/c1-6-11-23(28(41)31(44)35-18-26(40)36-24(29(34)42)16-15-22-12-8-7-9-13-22)37-30(43)25-14-10-17-39(25)32(45)27(21(4)5)38-33(46)47-19-20(2)3/h7-9,12-13,20-21,23-25,27H,6,10-11,14-19H2,1-5H3,(H2,34,42)(H,35,44)(H,36,40)(H,37,43)(H,38,46)/t23?,24-,25-,27-/m0/s1
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PubMed
6.70E+3 -30.0n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9714
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-1-ca...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CC1CCCCC1)C(N)=O
Show InChI InChI=1S/C32H54N6O8/c1-6-11-22(27(40)30(43)34-17-25(39)35-23(28(33)41)16-21-12-8-7-9-13-21)36-29(42)24-14-10-15-38(24)31(44)26(20(4)5)37-32(45)46-18-19(2)3/h19-24,26H,6-18H2,1-5H3,(H2,33,41)(H,34,43)(H,35,39)(H,36,42)(H,37,45)/t22?,23-,24-,26-/m0/s1
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PubMed
8.00E+3 -29.6n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9721
PNG
((3S)-3-carbamoyl-3-(2-{3-[(2S)-2-[(2S)-2-cyclohexy...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OCC(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(N)=O
Show InChI InChI=1S/C31H52N6O10/c1-6-10-20(26(41)30(45)33-15-23(38)34-21(27(32)42)14-24(39)40)35-28(43)22(13-17(2)3)36-29(44)25(19-11-8-7-9-12-19)37-31(46)47-16-18(4)5/h17-22,25H,6-16H2,1-5H3,(H2,32,42)(H,33,45)(H,34,38)(H,35,43)(H,36,44)(H,37,46)(H,39,40)/t20?,21-,22-,25-/m0/s1
PDB
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DrugBank
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UniChem

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Article
PubMed
8.40E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9716
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-1-ca...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O
Show InChI InChI=1S/C36H50N6O8/c1-6-10-26(40-33(46)28-13-9-16-42(28)35(48)30(22(4)5)41-36(49)50-20-21(2)3)31(44)34(47)38-19-29(43)39-27(32(37)45)18-23-14-15-24-11-7-8-12-25(24)17-23/h7-8,11-12,14-15,17,21-22,26-28,30H,6,9-10,13,16,18-20H2,1-5H3,(H2,37,45)(H,38,47)(H,39,43)(H,40,46)(H,41,49)/t26?,27-,28-,30-/m0/s1
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PubMed
1.20E+4 -28.6n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9717
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-1-ca...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O
Show InChI InChI=1S/C32H48N6O8/c1-6-11-22(27(40)30(43)34-17-25(39)35-23(28(33)41)16-21-12-8-7-9-13-21)36-29(42)24-14-10-15-38(24)31(44)26(20(4)5)37-32(45)46-18-19(2)3/h7-9,12-13,19-20,22-24,26H,6,10-11,14-18H2,1-5H3,(H2,33,41)(H,34,43)(H,35,39)(H,36,42)(H,37,45)/t22?,23-,24-,26-/m0/s1
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Article
PubMed
1.50E+4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9706
PNG
(P3-capped alpha-ketoamide inhibitor 20 | lithio (2...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C([O-])=O
Show InChI InChI=1S/C29H49N5O9/c1-8-11-19(24(36)26(38)30-14-21(35)32-23(28(40)41)18(7)9-2)31-25(37)20-12-10-13-34(20)27(39)22(17(5)6)33-29(42)43-15-16(3)4/h16-20,22-23H,8-15H2,1-7H3,(H,30,38)(H,31,37)(H,32,35)(H,33,42)(H,40,41)/p-1/t18-,19?,20-,22-,23-/m0/s1
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Article
PubMed
1.50E+4 -28.0n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9705
PNG
(P3-capped alpha-ketoamide inhibitor 19 | methyl (2...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)OC
Show InChI InChI=1S/C30H51N5O9/c1-9-12-20(25(37)27(39)31-15-22(36)33-24(19(7)10-2)29(41)43-8)32-26(38)21-13-11-14-35(21)28(40)23(18(5)6)34-30(42)44-16-17(3)4/h17-21,23-24H,9-16H2,1-8H3,(H,31,39)(H,32,38)(H,33,36)(H,34,42)/t19-,20?,21-,23-,24-/m0/s1
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PubMed
1.50E+4 -28.0n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9713
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-1-ca...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(N)=O
Show InChI InChI=1S/C29H50N6O8/c1-8-10-19(24(37)27(40)31-14-22(36)32-20(25(30)38)13-16(2)3)33-26(39)21-11-9-12-35(21)28(41)23(18(6)7)34-29(42)43-15-17(4)5/h16-21,23H,8-15H2,1-7H3,(H2,30,38)(H,31,40)(H,32,36)(H,33,39)(H,34,42)/t19?,20-,21-,23-/m0/s1
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PubMed
1.60E+4 -27.8n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9708
PNG
((5S)-5-carbamoyl-5-[2-(3-{[(2S)-1-[(2S)-3-methyl-2...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CCCC(O)=O)C(N)=O
Show InChI InChI=1S/C29H48N6O10/c1-6-9-18(24(39)27(42)31-14-21(36)32-19(25(30)40)10-7-12-22(37)38)33-26(41)20-11-8-13-35(20)28(43)23(17(4)5)34-29(44)45-15-16(2)3/h16-20,23H,6-15H2,1-5H3,(H2,30,40)(H,31,42)(H,32,36)(H,33,41)(H,34,44)(H,37,38)/t18?,19-,20-,23-/m0/s1
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Article
PubMed
1.80E+4 -27.5n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9703
PNG
(5-ethyl 1-methyl (2S)-2-[2-(3-{[(2S)-1-[(2S)-3-met...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CCC(=O)OCC)C(=O)OC
Show InChI InChI=1S/C31H51N5O11/c1-8-11-20(26(39)28(41)32-16-23(37)33-21(30(43)45-7)13-14-24(38)46-9-2)34-27(40)22-12-10-15-36(22)29(42)25(19(5)6)35-31(44)47-17-18(3)4/h18-22,25H,8-17H2,1-7H3,(H,32,41)(H,33,37)(H,34,40)(H,35,44)/t20?,21-,22-,25-/m0/s1
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Article
PubMed
2.00E+4 -27.3n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9732
PNG
(P3-capped alpha-ketoamide inhibitor 48 | tert-buty...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)NCc1ccccc1
Show InChI InChI=1S/C33H49N5O7/c1-5-13-24(28(40)30(42)35-21-26(39)34-20-22-14-8-6-9-15-22)36-29(41)25-18-12-19-38(25)31(43)27(23-16-10-7-11-17-23)37-32(44)45-33(2,3)4/h6,8-9,14-15,23-25,27H,5,7,10-13,16-21H2,1-4H3,(H,34,39)(H,35,42)(H,36,41)(H,37,44)/t24?,25-,27-/m0/s1
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PubMed
4.50E+4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9711
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-1-ca...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@H](C(N)=O)C(C)(C)C
Show InChI InChI=1S/C29H50N6O8/c1-9-11-18(22(37)26(40)31-14-20(36)33-23(24(30)38)29(6,7)8)32-25(39)19-12-10-13-35(19)27(41)21(17(4)5)34-28(42)43-15-16(2)3/h16-19,21,23H,9-15H2,1-8H3,(H2,30,38)(H,31,40)(H,32,39)(H,33,36)(H,34,42)/t18?,19-,21-,23+/m0/s1
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Article
PubMed
5.30E+4 -24.8n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9701
PNG
(1,4-dimethyl (2S)-2-[2-(3-{[(2S)-1-[(2S)-3-methyl-...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CC(=O)OC)C(=O)OC
Show InChI InChI=1S/C29H47N5O11/c1-8-10-18(24(37)26(39)30-14-21(35)31-19(28(41)44-7)13-22(36)43-6)32-25(38)20-11-9-12-34(20)27(40)23(17(4)5)33-29(42)45-15-16(2)3/h16-20,23H,8-15H2,1-7H3,(H,30,39)(H,31,35)(H,32,38)(H,33,42)/t18?,19-,20-,23-/m0/s1
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Article
PubMed
5.50E+4 -24.7n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9733
PNG
(P3-capped alpha-ketoamide inhibitor 49 | tert-buty...)
Show SMILES CCCC(NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)NCc1ccccc1
Show InChI InChI=1S/C34H53N5O7/c1-7-14-25(29(41)32(44)36-21-27(40)35-20-23-15-10-8-11-16-23)37-30(42)26(19-22(2)3)38-31(43)28(24-17-12-9-13-18-24)39-33(45)46-34(4,5)6/h8,10-11,15-16,22,24-26,28H,7,9,12-14,17-21H2,1-6H3,(H,35,40)(H,36,44)(H,37,42)(H,38,43)(H,39,45)/t25?,26-,28-/m0/s1
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PubMed
8.10E+4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9707
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-5-am...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(N)=O
Show InChI InChI=1S/C29H51N7O8/c1-6-10-19(24(38)27(41)32-15-22(37)33-20(25(31)39)11-7-8-13-30)34-26(40)21-12-9-14-36(21)28(42)23(18(4)5)35-29(43)44-16-17(2)3/h17-21,23H,6-16,30H2,1-5H3,(H2,31,39)(H,32,41)(H,33,37)(H,34,40)(H,35,43)/t19?,20-,21-,23-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.20E+4 -23.7n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9704
PNG
(1,5-dilithio (2S)-2-[2-(3-{[(2S)-1-[(2S)-3-methyl-...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CCC([O-])=O)C([O-])=O
Show InChI InChI=1S/C28H45N5O11/c1-6-8-17(23(37)25(39)29-13-20(34)30-18(27(41)42)10-11-21(35)36)31-24(38)19-9-7-12-33(19)26(40)22(16(4)5)32-28(43)44-14-15(2)3/h15-19,22H,6-14H2,1-5H3,(H,29,39)(H,30,34)(H,31,38)(H,32,43)(H,35,36)(H,41,42)/p-2/t17?,18-,19-,22-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5>-23.2n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9702
PNG
(1,4-disodium (2S)-2-[2-(3-{[(2S)-1-[(2S)-3-methyl-...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CC([O-])=O)C([O-])=O
Show InChI InChI=1S/C27H43N5O11/c1-6-8-16(22(36)24(38)28-12-19(33)29-17(26(40)41)11-20(34)35)30-23(37)18-9-7-10-32(18)25(39)21(15(4)5)31-27(42)43-13-14(2)3/h14-18,21H,6-13H2,1-5H3,(H,28,38)(H,29,33)(H,30,37)(H,31,42)(H,34,35)(H,40,41)/p-2/t16?,17-,18-,21-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5>-23.2n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
HCV NS3-NS4A Serine Proteinase


(Hepatitis C virus (HCV genotype 1a, isolate H))
BDBM9709
PNG
(2-methylpropyl N-[(2S)-1-[(2S)-2-({1-[({[(1S)-1-ca...)
Show SMILES CCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)C(=O)C(=O)NCC(=O)N[C@@H](CCO)C(N)=O
Show InChI InChI=1S/C27H46N6O9/c1-6-8-17(22(36)25(39)29-13-20(35)30-18(10-12-34)23(28)37)31-24(38)19-9-7-11-33(19)26(40)21(16(4)5)32-27(41)42-14-15(2)3/h15-19,21,34H,6-14H2,1-5H3,(H2,28,37)(H,29,39)(H,30,35)(H,31,38)(H,32,41)/t17?,18-,19-,21-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.11E+5 -23.0n/an/an/an/an/a6.530



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...


Bioorg Med Chem Lett 15: 4180-4 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.091
BindingDB Entry DOI: 10.7270/Q2KS6PSP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%