Affinity Data by PubMed id=1613746

PubMed code 1613746

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453183 (CHEMBL2114060) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.423	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453183 (CHEMBL2114060) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.522	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453188 (CHEMBL2115124) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.533	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453188 (CHEMBL2115124) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.876	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453182 (CHEMBL2114061) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453182 (CHEMBL2114061) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453186 (CHEMBL2115125) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453186 (CHEMBL2115125) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453187 (CHEMBL2115123) Show SMILES CC(=O)O[C@@H]1CC2CC1N(Cc1ccccc1)C2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453190 (CHEMBL2114059) Show SMILES CC(=O)O[C@H]1CC2CC1N(Cc1ccccc1)C2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453184 (CHEMBL2115122) Show SMILES CN1CC2CC1C[C@@H]2OC(C)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453184 (CHEMBL2115122) Show SMILES CN1CC2CC1C[C@@H]2OC(C)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453190 (CHEMBL2114059) Show SMILES CC(=O)O[C@H]1CC2CC1N(Cc1ccccc1)C2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]QNB binding to m3 receptor transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006546 (Acetic acid 2-benzyl-2-aza-bicyclo[2.2.1]hept-5-yl...) Show SMILES CC(=O)OC1CC2CC1CN2Cc1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006549 (Acetic acid 2-methyl-2-aza-bicyclo[2.2.1]hept-6-yl...) Show SMILES CN1CC2CC(OC(C)=O)C1C2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50453189 (CHEMBL2114058) Show SMILES CN1CC2CC1C[C@H]2OC(C)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M1 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006546 (Acetic acid 2-benzyl-2-aza-bicyclo[2.2.1]hept-5-yl...) Show SMILES CC(=O)OC1CC2CC1CN2Cc1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.69E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453189 (CHEMBL2114058) Show SMILES CN1CC2CC1C[C@H]2OC(C)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.77E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50006549 (Acetic acid 2-methyl-2-aza-bicyclo[2.2.1]hept-6-yl...) Show SMILES CN1CC2CC(OC(C)=O)C1C2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic receptor M2 and M3 (RAT)	BDBM50453187 (CHEMBL2115123) Show SMILES CC(=O)O[C@@H]1CC2CC1N(Cc1ccccc1)C2 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.76E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-QNB binding to Muscarinic acetylcholine receptor M3 transfected with CHO cell				Citation and Details
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%