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PubMed code 16140010

Compile data set for download or QSAR
Found 32 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172907
PNG
(3,4-diarylpyrazoline derivative | CHEMBL383580)
Show SMILES CN=C(NS(=O)(=O)N1CCSCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H24ClN5O2S2/c1-23-21(25-31(28,29)26-11-13-30-14-12-26)27-15-19(16-5-3-2-4-6-16)20(24-27)17-7-9-18(22)10-8-17/h2-10,19H,11-15H2,1H3,(H,23,25)
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24n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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25n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172899
PNG
(3,4-diarylpyrazoline derivative | CHEMBL195050)
Show SMILES CCN(CC)S(=O)(=O)NC(=NC)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H26ClN5O2S/c1-4-26(5-2)30(28,29)25-21(23-3)27-15-19(16-9-7-6-8-10-16)20(24-27)17-11-13-18(22)14-12-17/h6-14,19H,4-5,15H2,1-3H3,(H,23,25)
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30n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172906
PNG
(3,4-diarylpyrazoline derivative | CHEMBL371829)
Show SMILES CN=C(NS(=O)(=O)N(C)C(C)C)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H26ClN5O2S/c1-15(2)26(4)30(28,29)25-21(23-3)27-14-19(16-8-6-5-7-9-16)20(24-27)17-10-12-18(22)13-11-17/h5-13,15,19H,14H2,1-4H3,(H,23,25)
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32n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50312823
PNG
((S)-3-(4-chlorophenyl)-N-methyl-4-phenyl-N'-(piper...)
Show SMILES CNC(=NS(=O)(=O)N1CCCCC1)N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H26ClN5O2S/c1-24-22(26-31(29,30)27-14-6-3-7-15-27)28-16-20(17-8-4-2-5-9-17)21(25-28)18-10-12-19(23)13-11-18/h2,4-5,8-13,20H,3,6-7,14-16H2,1H3,(H,24,26)/t20-/m1/s1
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58n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172897
PNG
(3,4-diarylpyrazoline derivative | CHEMBL194566)
Show SMILES CCN(CC)S(=O)(=O)NC(=NC(C)C)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H30ClN5O2S/c1-5-28(6-2)32(30,31)27-23(25-17(3)4)29-16-21(18-10-8-7-9-11-18)22(26-29)19-12-14-20(24)15-13-19/h7-15,17,21H,5-6,16H2,1-4H3,(H,25,27)
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60n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172910
PNG
(3,4-diarylpyrazoline derivative | CHEMBL194351)
Show SMILES CN=C(NS(=O)(=O)N1CCOCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H24ClN5O3S/c1-23-21(25-31(28,29)26-11-13-30-14-12-26)27-15-19(16-5-3-2-4-6-16)20(24-27)17-7-9-18(22)10-8-17/h2-10,19H,11-15H2,1H3,(H,23,25)
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75n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172903
PNG
(3,4-diarylpyrazoline derivative | CHEMBL364300)
Show SMILES CCN(C)S(=O)(=O)NC(=NC)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C20H24ClN5O2S/c1-4-25(3)29(27,28)24-20(22-2)26-14-18(15-8-6-5-7-9-15)19(23-26)16-10-12-17(21)13-11-16/h5-13,18H,4,14H2,1-3H3,(H,22,24)
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117n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172902
PNG
(3,4-diarylpyrazoline derivative | CHEMBL197099)
Show SMILES CN=C(NS(=O)(=O)N1CCCCCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H30ClN5O2S/c1-26-24(28-33(31,32)29-16-8-3-2-4-9-17-29)30-18-22(19-10-6-5-7-11-19)23(27-30)20-12-14-21(25)15-13-20/h5-7,10-15,22H,2-4,8-9,16-18H2,1H3,(H,26,28)
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125n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172905
PNG
(3,4-diarylpyrazoline derivative | CHEMBL196048)
Show SMILES CCN(CC)S(=O)(=O)NC(=NC)N1CC(C(=N1)c1ccc(Cl)cc1)c1cccnc1
Show InChI InChI=1S/C20H25ClN6O2S/c1-4-26(5-2)30(28,29)25-20(22-3)27-14-18(16-7-6-12-23-13-16)19(24-27)15-8-10-17(21)11-9-15/h6-13,18H,4-5,14H2,1-3H3,(H,22,25)
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141n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172898
PNG
(3,4-diarylpyrazoline derivative | 3-(4-chloropheny...)
Show SMILES CN=C(NS(=O)(=O)N1CCCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H26ClN5O2S/c1-24-22(26-31(29,30)27-14-6-3-7-15-27)28-16-20(17-8-4-2-5-9-17)21(25-28)18-10-12-19(23)13-11-18/h2,4-5,8-13,20H,3,6-7,14-16H2,1H3,(H,24,26)
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152n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172900
PNG
(3,4-diarylpyrazoline derivative | CHEMBL197040)
Show SMILES CN=C(NS(=O)(=O)N1CCCCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H28ClN5O2S/c1-25-23(27-32(30,31)28-15-7-2-3-8-16-28)29-17-21(18-9-5-4-6-10-18)22(26-29)19-11-13-20(24)14-12-19/h4-6,9-14,21H,2-3,7-8,15-17H2,1H3,(H,25,27)
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155n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172901
PNG
(3,4-diarylpyrazoline derivative | CHEMBL372697)
Show SMILES CCN=C(NS(=O)(=O)N(CC)CC)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H28ClN5O2S/c1-4-24-22(26-31(29,30)27(5-2)6-3)28-16-20(17-10-8-7-9-11-17)21(25-28)18-12-14-19(23)15-13-18/h7-15,20H,4-6,16H2,1-3H3,(H,24,26)
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209n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172909
PNG
(3,4-diarylpyrazoline derivative | CHEMBL372650)
Show SMILES CN=C(NS(=O)(=O)N(C)C)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C19H22ClN5O2S/c1-21-19(23-28(26,27)24(2)3)25-13-17(14-7-5-4-6-8-14)18(22-25)15-9-11-16(20)12-10-15/h4-12,17H,13H2,1-3H3,(H,21,23)
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223n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172904
PNG
(3,4-diarylpyrazoline derivative | CHEMBL196989)
Show SMILES CN=C(NS(=O)(=O)N1CCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H24ClN5O2S/c1-23-21(25-30(28,29)26-13-5-6-14-26)27-15-19(16-7-3-2-4-8-16)20(24-27)17-9-11-18(22)12-10-17/h2-4,7-12,19H,5-6,13-15H2,1H3,(H,23,25)
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231n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50370660
PNG
(CHEMBL1788275)
Show SMILES CNC(=NS(=O)(=O)N1CCCCC1)N1C[C@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H26ClN5O2S/c1-24-22(26-31(29,30)27-14-6-3-7-15-27)28-16-20(17-8-4-2-5-9-17)21(25-28)18-10-12-19(23)13-11-18/h2,4-5,8-13,20H,3,6-7,14-16H2,1H3,(H,24,26)/t20-/m0/s1
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763n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (human))
BDBM50172908
PNG
(3,4-diarylpyrazoline derivative | CHEMBL425912)
Show SMILES CN=C(NS(=O)(=O)N1CCS(=O)(=O)CC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H24ClN5O4S2/c1-23-21(25-33(30,31)26-11-13-32(28,29)14-12-26)27-15-19(16-5-3-2-4-6-16)20(24-27)17-7-9-18(22)10-8-17/h2-10,19H,11-15H2,1H3,(H,23,25)
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832n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 1


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172900
PNG
(3,4-diarylpyrazoline derivative | CHEMBL197040)
Show SMILES CN=C(NS(=O)(=O)N1CCCCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H28ClN5O2S/c1-25-23(27-32(30,31)28-15-7-2-3-8-16-28)29-17-21(18-9-5-4-6-10-18)22(26-29)19-11-13-20(24)14-12-19/h4-6,9-14,21H,2-3,7-8,15-17H2,1H3,(H,25,27)
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1.03E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172906
PNG
(3,4-diarylpyrazoline derivative | CHEMBL371829)
Show SMILES CN=C(NS(=O)(=O)N(C)C(C)C)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H26ClN5O2S/c1-15(2)26(4)30(28,29)25-21(23-3)27-14-19(16-8-6-5-7-9-16)20(24-27)17-10-12-18(22)13-11-17/h5-13,15,19H,14H2,1-4H3,(H,23,25)
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1.13E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172898
PNG
(3,4-diarylpyrazoline derivative | 3-(4-chloropheny...)
Show SMILES CN=C(NS(=O)(=O)N1CCCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H26ClN5O2S/c1-24-22(26-31(29,30)27-14-6-3-7-15-27)28-16-20(17-8-4-2-5-9-17)21(25-28)18-10-12-19(23)13-11-18/h2,4-5,8-13,20H,3,6-7,14-16H2,1H3,(H,24,26)
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1.32E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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1.58E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172904
PNG
(3,4-diarylpyrazoline derivative | CHEMBL196989)
Show SMILES CN=C(NS(=O)(=O)N1CCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H24ClN5O2S/c1-23-21(25-30(28,29)26-13-5-6-14-26)27-15-19(16-7-3-2-4-8-16)20(24-27)17-9-11-18(22)12-10-17/h2-4,7-12,19H,5-6,13-15H2,1H3,(H,23,25)
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1.60E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172903
PNG
(3,4-diarylpyrazoline derivative | CHEMBL364300)
Show SMILES CCN(C)S(=O)(=O)NC(=NC)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C20H24ClN5O2S/c1-4-25(3)29(27,28)24-20(22-2)26-14-18(15-8-6-5-7-9-15)19(23-26)16-10-12-17(21)13-11-16/h5-13,18H,4,14H2,1-3H3,(H,22,24)
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1.87E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172902
PNG
(3,4-diarylpyrazoline derivative | CHEMBL197099)
Show SMILES CN=C(NS(=O)(=O)N1CCCCCCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C24H30ClN5O2S/c1-26-24(28-33(31,32)29-16-8-3-2-4-9-17-29)30-18-22(19-10-6-5-7-11-19)23(27-30)20-12-14-21(25)15-13-20/h5-7,10-15,22H,2-4,8-9,16-18H2,1H3,(H,26,28)
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2.58E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172897
PNG
(3,4-diarylpyrazoline derivative | CHEMBL194566)
Show SMILES CCN(CC)S(=O)(=O)NC(=NC(C)C)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C23H30ClN5O2S/c1-5-28(6-2)32(30,31)27-23(25-17(3)4)29-16-21(18-10-8-7-9-11-18)22(26-29)19-12-14-20(24)15-13-19/h7-15,17,21H,5-6,16H2,1-4H3,(H,25,27)
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2.76E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172901
PNG
(3,4-diarylpyrazoline derivative | CHEMBL372697)
Show SMILES CCN=C(NS(=O)(=O)N(CC)CC)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H28ClN5O2S/c1-4-24-22(26-31(29,30)27(5-2)6-3)28-16-20(17-10-8-7-9-11-17)21(25-28)18-12-14-19(23)15-13-18/h7-15,20H,4-6,16H2,1-3H3,(H,24,26)
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2.86E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172899
PNG
(3,4-diarylpyrazoline derivative | CHEMBL195050)
Show SMILES CCN(CC)S(=O)(=O)NC(=NC)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H26ClN5O2S/c1-4-26(5-2)30(28,29)25-21(23-3)27-15-19(16-9-7-6-8-10-16)20(24-27)17-11-13-18(22)14-12-17/h6-14,19H,4-5,15H2,1-3H3,(H,23,25)
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3.27E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50312823
PNG
((S)-3-(4-chlorophenyl)-N-methyl-4-phenyl-N'-(piper...)
Show SMILES CNC(=NS(=O)(=O)N1CCCCC1)N1C[C@@H](C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C22H26ClN5O2S/c1-24-22(26-31(29,30)27-14-6-3-7-15-27)28-16-20(17-8-4-2-5-9-17)21(25-28)18-10-12-19(23)13-11-18/h2,4-5,8-13,20H,3,6-7,14-16H2,1H3,(H,24,26)/t20-/m1/s1
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3.50E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172907
PNG
(3,4-diarylpyrazoline derivative | CHEMBL383580)
Show SMILES CN=C(NS(=O)(=O)N1CCSCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H24ClN5O2S2/c1-23-21(25-31(28,29)26-11-13-30-14-12-26)27-15-19(16-5-3-2-4-6-16)20(24-27)17-7-9-18(22)10-8-17/h2-10,19H,11-15H2,1H3,(H,23,25)
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3.53E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172909
PNG
(3,4-diarylpyrazoline derivative | CHEMBL372650)
Show SMILES CN=C(NS(=O)(=O)N(C)C)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C19H22ClN5O2S/c1-21-19(23-28(26,27)24(2)3)25-13-17(14-7-5-4-6-8-14)18(22-25)15-9-11-16(20)12-10-15/h4-12,17H,13H2,1-3H3,(H,21,23)
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3.84E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172910
PNG
(3,4-diarylpyrazoline derivative | CHEMBL194351)
Show SMILES CN=C(NS(=O)(=O)N1CCOCC1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C21H24ClN5O3S/c1-23-21(25-31(28,29)26-11-13-30-14-12-26)27-15-19(16-5-3-2-4-6-16)20(24-27)17-7-9-18(22)10-8-17/h2-10,19H,11-15H2,1H3,(H,23,25)
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5.37E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (human))
BDBM50172905
PNG
(3,4-diarylpyrazoline derivative | CHEMBL196048)
Show SMILES CCN(CC)S(=O)(=O)NC(=NC)N1CC(C(=N1)c1ccc(Cl)cc1)c1cccnc1
Show InChI InChI=1S/C20H25ClN6O2S/c1-4-26(5-2)30(28,29)25-20(22-3)27-14-18(16-7-6-12-23-13-16)19(24-27)15-8-10-17(21)11-9-15/h6-13,18H,4-5,14H2,1-3H3,(H,22,25)
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9.08E+3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of specific CP-55940 binding in CHO cells stably transfected with human cannabinoid receptor 2


Bioorg Med Chem Lett 15: 4794-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.054
BindingDB Entry DOI: 10.7270/Q2W959ZZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%