Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50016760
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173287(4-[3-(4-Fluoro-phenyl)-5-methyl-isoxazol-4-yl]-ben...)
Affinity DataIC50:  2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173288(4-(5-Fluoromethyl-3-phenyl-isoxazol-4-yl)-benzenes...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173288(4-(5-Fluoromethyl-3-phenyl-isoxazol-4-yl)-benzenes...)
Affinity DataIC50:  2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173290(4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benz...)
Affinity DataIC50:  2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
University Of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173289(2-Fluoro-4-(5-methyl-3-phenyl-isoxazol-4-yl)-benze...)
Affinity DataIC50:  2nMAssay Description:Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM13063(4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sul...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of California Los Angeles

Curated by ChEMBL
LigandPNGBDBM50173290(4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benz...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against human recombinant cyclooxygenase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed