Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 3174
LigandPNGBDBM28962(cyclohexyl sulfone-based compound, 5 | {4-[(4-chlo...)
Affinity DataEC50:  4.70nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28990(4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoropheny...)
Affinity DataEC50:  10.7nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28964(cyclohexyl sulfone-based compound, 7 | {4-[(4-chlo...)
Affinity DataEC50:  148nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28965(2-{1-[(4-chlorobenzene)sulfonyl]-4-(iodomethyl)cyc...)
Affinity DataEC50:  14.3nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28966(cyclohexyl sulfone-based compound, 9 | {4-[(4-chlo...)
Affinity DataEC50:  0.510nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28967(N-({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluorop...)
Affinity DataEC50:  1.30nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28968(({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluorophe...)
Affinity DataEC50:  1nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28969(cyclohexyl sulfone-based compound, 12 | methyl N-(...)
Affinity DataEC50:  2.20nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28970([({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  1.70nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28971(1-({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluorop...)
Affinity DataEC50:  1nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28972(2-{1-[(4-chlorobenzene)sulfonyl]-4-[(cyclopropanes...)
Affinity DataEC50:  1.40nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28973(2-{1-[(4-chlorobenzene)sulfonyl]-4-[(trifluorometh...)
Affinity DataEC50:  21.5nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28974(2-{4-[(benzenesulfonyl)methyl]-1-[(4-chlorobenzene...)
Affinity DataEC50:  8.80nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28975(2-[({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoro...)
Affinity DataEC50:  0.650nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28976(2-{1-[(4-chlorobenzene)sulfonyl]-4-{[(2-methoxyben...)
Affinity DataEC50:  0.510nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28977(2-[({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoro...)
Affinity DataEC50:  2.10nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28978(cyclohexyl sulfone-based compound, 22 | {4-[(4-chl...)
Affinity DataEC50:  4.20nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28979(cyclohexyl sulfone-based compound, 23 | {4-[(4-chl...)
Affinity DataEC50:  1.10nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28980(1-[({4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoro...)
Affinity DataEC50:  0.360nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28981(4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoropheny...)
Affinity DataEC50:  510nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28982(cyclohexyl sulfone-based compound, 28 | {4-[(4-chl...)
Affinity DataEC50:  1.90nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28983(N-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  35nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28984(N-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  4.20nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28985(N-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  0.820nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28986(N-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  0.650nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
LigandPNGBDBM28987(N-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  0.25nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28988(N-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  0.660nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28989(N-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  0.150nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28963(2-{4-[(4-chlorobenzene)sulfonyl]-4-(2,5-difluoroph...)
Affinity DataEC50:  21.2nMAssay Description:A whole-cell gamma-secretase inhibition assay using SHSY5Y neuroblastoma cells in which human gamma-secretase catalyzes the breakdown of the overexpr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed