Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 1057
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8509((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-(...)
Affinity DataIC50:  37nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8513((2R)-5-[(aminiumylmethanimidoyl)amino]-2-[(4-fluor...)
Affinity DataIC50:  40nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8501((2R)-2-cyclohexyl-2-[(4-fluoro-3-methylbenzene)sul...)
Affinity DataIC50:  42nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8512((2R)-3-(2-aminiumylethoxy)-2-[(4-fluoro-3-methylbe...)
Affinity DataIC50:  48nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8502((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  50nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8507((2R)-3-cyclopropyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  51nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8503((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  54nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8511((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-(...)
Affinity DataIC50:  57nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8510((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-[...)
Affinity DataIC50:  59nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8500((2R)-2-cyclopentyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  64nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8508((2R,3S)-3-cyclopropyl-2-[(4-fluoro-3-methylbenzene...)
Affinity DataIC50:  65nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8505((2R,3S)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-...)
Affinity DataIC50:  67nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8506((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  67nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8496((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  70nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8514(4-[(3R)-3-[(4-fluoro-3-methylbenzene)sulfonamido]-...)
Affinity DataIC50:  75nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8495((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  100nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8498((2R)-2-cyclopropyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  120nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8504(2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-hydrox...)
Affinity DataIC50:  120nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8494((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  130nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8499((2R)-2-cyclobutyl-2-[(4-fluoro-3-methylbenzene)sul...)
Affinity DataIC50:  130nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8479((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  130nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8476((2R)-2-[(4-fluorobenzene)sulfonamido]-N-hydroxy-3-...)
Affinity DataIC50:  290nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8497((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  300nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8478((2R)-N-hydroxy-3-methyl-2-[(3-methylbenzene)sulfon...)
Affinity DataIC50:  400nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8488((2R)-2-[(4-fluoronaphthalene-1-)sulfonamido]-N-hyd...)
Affinity DataIC50:  460nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8490((2R)-2-{[4-fluoro-3-(hydroxymethyl)benzene]sulfona...)
Affinity DataIC50:  600nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8493((2R)-N-hydroxy-3-methyl-2-{[5-(1,2,3-thiadiazol-5-...)
Affinity DataIC50:  810nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8466((2R)-N-hydroxy-2-[(4-methoxybenzene)sulfonamido]-3...)
Affinity DataIC50:  900nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8473((2R)-2-benzenesulfonamido-N-hydroxy-3-methylbutana...)
Affinity DataIC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  1.20E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8491((2R)-2-{[4-fluoro-2-(hydroxymethyl)benzene]sulfona...)
Affinity DataIC50:  1.31E+3nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8492((2R)-2-[(5-chlorothiophene-2-)sulfonamido]-N-hydro...)
Affinity DataIC50:  1.31E+3nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8489((2R)-N-hydroxy-2-[(4-hydroxy-3-methylbenzene)sulfo...)
Affinity DataIC50:  1.64E+3nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8471((2R)-N-hydroxy-2-[(4-methoxybenzene)[2-(thiophen-3...)
Affinity DataIC50:  2.10E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8475((2R)-2-[(3-fluorobenzene)sulfonamido]-N-hydroxy-3-...)
Affinity DataIC50:  2.80E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8477((2R)-N-hydroxy-3-methyl-2-[(4-methylbenzene)sulfon...)
Affinity DataIC50:  3.00E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8470((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-4-ylm...)
Affinity DataIC50:  3.10E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8481((2R)-2-[(3-fluoro-4-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  5.18E+3nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8474((2R)-2-[(2-fluorobenzene)sulfonamido]-N-hydroxy-3-...)
Affinity DataIC50:  6.60E+3nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8482((2R)-N-hydroxy-3-methyl-2-[(2-phenylethane)sulfona...)
Affinity DataIC50:  1.19E+4nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8483((2R)-2-{[(3-chlorophenyl)methane]sulfonamido}-N-hy...)
Affinity DataIC50:  1.66E+4nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8472((2R)-N-hydroxy-2-{[2-(1H-imidazol-1-yl)ethyl](4-me...)
Affinity DataIC50:  1.91E+4nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8468(N-[(3R)-1-hydroxy-2-oxopyrrolidin-3-yl]-4-methoxyb...)
Affinity DataIC50: >4.00E+4nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8467((2R)-N-hydroxy-3-methyl-2-[N-(pyridin-3-ylmethyl)a...)
Affinity DataIC50: >4.00E+4nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8487((2R)-N-hydroxy-3-methyl-2-[(4-phenylbenzene)sulfon...)
Affinity DataIC50: >4.00E+4nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8486((2R)-2-{[4-(benzyloxy)-3-methylbenzene]sulfonamido...)
Affinity DataIC50: >4.00E+4nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8485((2R)-N-hydroxy-3-methyl-2-[(4-phenoxybenzene)sulfo...)
Affinity DataIC50: >4.00E+4nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8484((2R)-2-[(4-butoxybenzene)sulfonamido]-N-hydroxy-3-...)
Affinity DataIC50: >4.00E+4nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8469((2R)-N-hydroxy-3-methyl-2-[(2,2,2-trifluoroethane)...)
Affinity DataIC50: >4.00E+4nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8480((2R)-N-hydroxy-3-methyl-2-{[4-(trifluoromethyl)ben...)
Affinity DataIC50: >4.00E+4nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed