Affinity Data by PubMed id=1635055

PubMed code 1635055

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholecystokinin receptor (MOUSE)	BDBM50006842 (2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropox...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) Article DOI: 10.1021/jm00092a003 BindingDB Entry DOI: 10.7270/Q2JM28MX
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (MOUSE)	BDBM50006838 (2-[2-(1H-Indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) Article DOI: 10.1021/jm00092a003 BindingDB Entry DOI: 10.7270/Q2JM28MX
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (MOUSE)	BDBM50006839 (2-[2-(1H-Indol-3-yl)-propyl]-3-(3-isopropoxy-pheny...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) Article DOI: 10.1021/jm00092a003 BindingDB Entry DOI: 10.7270/Q2JM28MX
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (MOUSE)	BDBM50006840 (2-[2-(1H-Indol-3-yl)-vinyl]-3-(3-isopropoxy-phenyl...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) Article DOI: 10.1021/jm00092a003 BindingDB Entry DOI: 10.7270/Q2JM28MX
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (MOUSE)	BDBM50006837 (2-[2-(1H-Indol-3-yl)-ethyl]-3-phenyl-3H-quinazolin...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) Article DOI: 10.1021/jm00092a003 BindingDB Entry DOI: 10.7270/Q2JM28MX
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (MOUSE)	BDBM50006836 (2-[2-(5-Bromo-1H-indol-3-yl)-vinyl]-3-(3-isopropox...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) Article DOI: 10.1021/jm00092a003 BindingDB Entry DOI: 10.7270/Q2JM28MX
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (MOUSE)	BDBM50006841 (2-[2-(1H-Indol-3-yl)-1-methyl-ethyl]-3-(3-isopropo...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Evaluated for inhibition of [125I]-CCK-8S binding to cholecystokinin CCK-B receptor from mouse brain membranes at a concentration of 10 microM (in vi...				J Med Chem 35: 2534-42 (1992) Article DOI: 10.1021/jm00092a003 BindingDB Entry DOI: 10.7270/Q2JM28MX
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%