Affinity Data by PubMed id=1635064

PubMed code 1635064

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Angiotensin II AT1B (RAT)	BDBM50006909 (2-Butyl-5-chloro-3-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to Angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50009714 (CHEMBL191 \| {2-Butyl-5-chloro-3-[2'-(2H-tetrazol-5...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50006911 (2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cyclop...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50006910 (2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cycloh...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50006908 (2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cycloh...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50006912 ((2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cyclo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50006914 ((2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cyclo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair
Angiotensin II AT1B (RAT)	BDBM50006913 ((2-Butyl-5-chloro-3-{4-[2-(2H-tetrazol-5-yl)-cyclo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit binding of radioligand [125I]-AII to angiotensin II receptor, type 1 in rat adrenal glomerulosa tis...				J Med Chem 35: 2658-67 (1992) Article DOI: 10.1021/jm00092a017 BindingDB Entry DOI: 10.7270/Q2930S4R
Eli Lilly and Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%