Compile Data Set for Download or QSAR
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Found 55 Enz. Inhib. hit(s) with all data for entry = 50000540
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000832(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  5nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007052(1-[3-(3-Phenyl-allyloxy)-phenyl]-1-thiazol-2-yl-pr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50:  14nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000832(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000832(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: <30nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007057(1-[3-(3-Phenyl-prop-2-ynyloxy)-phenyl]-1-thiazol-2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007051(1-[3-(Naphthalen-2-ylmethoxy)-phenyl]-1-thiazol-2-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  100nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)
Affinity DataIC50:  300nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000832(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  500nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000857(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)
Affinity DataIC50:  500nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000832(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  500nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007055(4-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  600nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007056(1-Thiazol-2-yl-1-[3-(3-o-tolyl-prop-2-ynyloxy)-phe...)
Affinity DataIC50:  600nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000832(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007052(1-[3-(3-Phenyl-allyloxy)-phenyl]-1-thiazol-2-yl-pr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000832(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  800nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007047(1-[3-(3,4-Difluoro-benzyloxy)-phenyl]-1-thiazol-2-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007060(1-(4-Methyl-thiazol-2-yl)-1-[3-(naphthalen-2-ylmet...)
Affinity DataIC50:  820nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007057(1-[3-(3-Phenyl-prop-2-ynyloxy)-phenyl]-1-thiazol-2...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007048(2-Methyl-1-[3-(naphthalen-2-ylmethoxy)-phenyl]-1-t...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007063(1-[3-(3,4-Dichloro-benzyloxy)-phenyl]-1-thiazol-2-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007058(1-Thiazol-2-yl-1-[3-(3-m-tolyl-prop-2-ynyloxy)-phe...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007062(2-{1-Methoxy-1-[3-(naphthalen-1-ylmethoxy)-phenyl]...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007053(CHEMBL73720 | [3-(Naphthalen-2-ylmethoxy)-phenyl]-...)
Affinity DataIC50:  5.10E+3nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)
Affinity DataIC50:  6.00E+3nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007043((3-Decyloxy-phenyl)-(5-methyl-1H-imidazol-2-yl)-me...)
Affinity DataIC50:  6.30E+3nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007054(5-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007050(CHEMBL71399 | [3-(Biphenyl-4-ylmethoxy)-phenyl]-(5...)
Affinity DataIC50:  7.00E+3nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007041((5-Methyl-1H-imidazol-2-yl)-[3-(naphthalen-2-ylmet...)
Affinity DataIC50:  7.60E+3nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007051(1-[3-(Naphthalen-2-ylmethoxy)-phenyl]-1-thiazol-2-...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007044(1-[3-(3-Phenyl-propoxy)-phenyl]-1-thiazol-2-yl-pro...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007042(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)
Affinity DataIC50:  1.20E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007045(2-[1-Methoxy-4-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of 5-lipoxygenase in mouse macrophages.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: >2.00E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007059(1-Thiazol-2-yl-1-[3-(3-p-tolyl-prop-2-ynyloxy)-phe...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007053(CHEMBL73720 | [3-(Naphthalen-2-ylmethoxy)-phenyl]-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007041((5-Methyl-1H-imidazol-2-yl)-[3-(naphthalen-2-ylmet...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007043((3-Decyloxy-phenyl)-(5-methyl-1H-imidazol-2-yl)-me...)
Affinity DataIC50: >3.00E+4nMAssay Description:Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007040(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007045(2-[1-Methoxy-4-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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