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PubMed code 16500101

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucagon receptor


(Homo sapiens (Human))
BDBM50183179
PNG
(CHEMBL380387 | naphthalen-1-yl-[4-(3-pyrrolidin-1-...)
Show SMILES O=C(c1ccc(OCCCN2CCCC2)cc1)c1cccc2ccccc12
Show InChI InChI=1S/C24H25NO2/c26-24(23-10-5-8-19-7-1-2-9-22(19)23)20-11-13-21(14-12-20)27-18-6-17-25-15-3-4-16-25/h1-2,5,7-14H,3-4,6,15-18H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]glucagon binding to glucagon receptor


Bioorg Med Chem Lett 16: 2719-23 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.013
BindingDB Entry DOI: 10.7270/Q2NP2418
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50183180
PNG
(4-[2-(4-methoxybenzylamino-propoxy)-phenyl]-naphth...)
Show SMILES COc1ccc(NCCCOc2ccc(cc2)C(=O)c2cccc3ccccc23)cc1
Show InChI InChI=1S/C27H25NO3/c1-30-23-16-12-22(13-17-23)28-18-5-19-31-24-14-10-21(11-15-24)27(29)26-9-4-7-20-6-2-3-8-25(20)26/h2-4,6-17,28H,5,18-19H2,1H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]glucagon binding to glucagon receptor


Bioorg Med Chem Lett 16: 2719-23 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.013
BindingDB Entry DOI: 10.7270/Q2NP2418
More data for this
Ligand-Target Pair
Glucagon receptor


(Homo sapiens (Human))
BDBM50183181
PNG
(CHEMBL208053 | naphthalen-1-yl-[4-(2-pyrrolidin-1-...)
Show SMILES O=C(c1ccc(OCCN2CCCC2)cc1)c1cccc2ccccc12
Show InChI InChI=1S/C23H23NO2/c25-23(22-9-5-7-18-6-1-2-8-21(18)22)19-10-12-20(13-11-19)26-17-16-24-14-3-4-15-24/h1-2,5-13H,3-4,14-17H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.50E+4n/an/an/an/an/an/a



Central Drug Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]glucagon binding to glucagon receptor


Bioorg Med Chem Lett 16: 2719-23 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.013
BindingDB Entry DOI: 10.7270/Q2NP2418
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%