Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(1A) dopamine receptor (RAT) | BDBM50007137![]() (1-Aminomethyl-3-(3-hydroxy-phenyl)-isochroman-5,6-...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007152![]() (1-Aminomethyl-3-(4-iodo-phenyl)-isochroman-5,6-dio...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007125![]() (3-Cyclohexyl-1-methylaminomethyl-isochroman-5,6-di...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007149![]() (1-Aminomethyl-3-cyclopentylmethyl-isochroman-5,6-d...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007147![]() (3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity towards alpha-2 adrenergic receptor using [3H]rauwolscine as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007123![]() (1-Aminomethyl-3-(4-bromo-phenyl)-isochroman-5,6-di...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50004822![]() ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) | PDB UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007127![]() (1-Aminomethyl-3-cyclooctyl-isochroman-5,6-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 122 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity towards alpha-2 adrenergic receptor using [3H]rauwolscine as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50453079![]() (CHEMBL2115213) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007128![]() (1-Aminomethyl-3-phenethyl-isochroman-5,6-diol | CH...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 248 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 271 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007139![]() (1-Aminomethyl-3-(3-methoxy-phenyl)-isochroman-5,6-...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007138![]() (3-Cyclohexyl-1-cyclopropylaminomethyl-isochroman-5...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 329 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007127![]() (1-Aminomethyl-3-cyclooctyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 342 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007130![]() (1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 374 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007153![]() (1-Aminomethyl-3-benzyloxymethyl-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 386 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007151![]() (1-Aminomethyl-3-prop-2-ynyl-isochroman-5,6-diol | ...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 407 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007150![]() (1-Aminomethyl-3-benzyl-isochroman-5,6-diol | CHEMB...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 443 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity towards alpha-2 adrenergic receptor using [3H]rauwolscine as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007145![]() (1-Aminomethyl-isochroman-5,6-diol spirocyclohexane...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 479 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007141![]() (1-Aminomethyl-3-benzhydryl-isochroman-5,6-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007137![]() (1-Aminomethyl-3-(3-hydroxy-phenyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007138![]() (3-Cyclohexyl-1-cyclopropylaminomethyl-isochroman-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 636 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007128![]() (1-Aminomethyl-3-phenethyl-isochroman-5,6-diol | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007146![]() (1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 704 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007125![]() (3-Cyclohexyl-1-methylaminomethyl-isochroman-5,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 724 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 736 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1C receptor using [125 I]-SCH23982 as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007139![]() (1-Aminomethyl-3-(3-methoxy-phenyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 764 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007149![]() (1-Aminomethyl-3-cyclopentylmethyl-isochroman-5,6-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 782 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 807 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007133![]() (1-Aminomethyl-3-butyl-isochroman-5,6-diol | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 825 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007133![]() (1-Aminomethyl-3-butyl-isochroman-5,6-diol | CHEMBL...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007135![]() (1-Aminomethyl-isochroman-5,6-diol | CHEMBL87958) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007152![]() (1-Aminomethyl-3-(4-iodo-phenyl)-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007151![]() (1-Aminomethyl-3-prop-2-ynyl-isochroman-5,6-diol | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1C receptor using [125 I]-SCH23982 as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007130![]() (1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007147![]() (3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007150![]() (1-Aminomethyl-3-benzyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1C receptor using [125 I]-SCH23982 as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50453080![]() (CHEMBL2114209) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007123![]() (1-Aminomethyl-3-(4-bromo-phenyl)-isochroman-5,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007153![]() (1-Aminomethyl-3-benzyloxymethyl-isochroman-5,6-dio...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007132![]() (1-(Benzylamino-methyl)-3-cyclohexyl-isochroman-5,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007142![]() (3-Cyclohexyl-1-[(methyl-prop-2-ynyl-amino)-methyl]...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007124![]() (1-[(Allyl-methyl-amino)-methyl]-3-cyclohexyl-isoch...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007141![]() (1-Aminomethyl-3-benzhydryl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007143![]() (1-Aminomethyl-3-(4-methoxy-benzyl)-isochroman-5,6-...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007143![]() (1-Aminomethyl-3-(4-methoxy-benzyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007131![]() (3-Cyclohexyl-1-[(3-hydroxy-propylamino)-methyl]-is...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007124![]() (1-[(Allyl-methyl-amino)-methyl]-3-cyclohexyl-isoch...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50453079![]() (CHEMBL2115213) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007135![]() (1-Aminomethyl-isochroman-5,6-diol | CHEMBL87958) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007145![]() (1-Aminomethyl-isochroman-5,6-diol spirocyclohexane...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007144![]() (3-Cyclohexyl-1-prop-2-ynylaminomethyl-isochroman-5...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007146![]() (1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50004822![]() ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1C receptor using [125 I]-SCH23982 as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1C receptor using [125 I]-SCH23982 as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007132![]() (1-(Benzylamino-methyl)-3-cyclohexyl-isochroman-5,6...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50453080![]() (CHEMBL2114209) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1C receptor using [125 I]-SCH23982 as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards beta-1 adrenergic receptor using [3H]-iodocyanopindolol as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards beta-1 adrenergic receptor using [3H]-iodocyanopindolol as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards beta-1 adrenergic receptor using [3H]-iodocyanopindolol as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards beta-1 adrenergic receptor using [3H]-iodocyanopindolol as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards beta-1 adrenergic receptor using [3H]-iodocyanopindolol as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards beta-1 adrenergic receptor using [3H]-iodocyanopindolol as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007142![]() (3-Cyclohexyl-1-[(methyl-prop-2-ynyl-amino)-methyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007144![]() (3-Cyclohexyl-1-prop-2-ynylaminomethyl-isochroman-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007131![]() (3-Cyclohexyl-1-[(3-hydroxy-propylamino)-methyl]-is...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | PDB Reactome pathway UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 2- receptor using [3H]ketanserin as radioligand in competitive binding assay | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity of the compound was evaluated by using [3H]-8-OH-DPAT radioligand by using competitive binding assay on 5-hydroxytryptamine 1A recep... | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.58E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007142![]() (3-Cyclohexyl-1-[(methyl-prop-2-ynyl-amino)-methyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007144![]() (3-Cyclohexyl-1-prop-2-ynylaminomethyl-isochroman-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007135![]() (1-Aminomethyl-isochroman-5,6-diol | CHEMBL87958) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 490 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007124![]() (1-[(Allyl-methyl-amino)-methyl]-3-cyclohexyl-isoch...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 650 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007137![]() (1-Aminomethyl-3-(3-hydroxy-phenyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 192 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007153![]() (1-Aminomethyl-3-benzyloxymethyl-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 204 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007139![]() (1-Aminomethyl-3-(3-methoxy-phenyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007147![]() (3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007147![]() (3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007127![]() (1-Aminomethyl-3-cyclooctyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007124![]() (1-[(Allyl-methyl-amino)-methyl]-3-cyclohexyl-isoch...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007143![]() (1-Aminomethyl-3-(4-methoxy-benzyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 237 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007150![]() (1-Aminomethyl-3-benzyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007145![]() (1-Aminomethyl-isochroman-5,6-diol spirocyclohexane...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.68E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007149![]() (1-Aminomethyl-3-cyclopentylmethyl-isochroman-5,6-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007128![]() (1-Aminomethyl-3-phenethyl-isochroman-5,6-diol | CH...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007123![]() (1-Aminomethyl-3-(4-bromo-phenyl)-isochroman-5,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 358 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007152![]() (1-Aminomethyl-3-(4-iodo-phenyl)-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.03E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50453079![]() (CHEMBL2115213) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 142 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.91E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007151![]() (1-Aminomethyl-3-prop-2-ynyl-isochroman-5,6-diol | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 286 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007130![]() (1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007146![]() (1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007130![]() (1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007142![]() (3-Cyclohexyl-1-[(methyl-prop-2-ynyl-amino)-methyl]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007147![]() (3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50453080![]() (CHEMBL2114209) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 232 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007153![]() (1-Aminomethyl-3-benzyloxymethyl-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 89 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007150![]() (1-Aminomethyl-3-benzyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007129![]() ((1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007127![]() (1-Aminomethyl-3-cyclooctyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007128![]() (1-Aminomethyl-3-phenethyl-isochroman-5,6-diol | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007130![]() (1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007132![]() (1-(Benzylamino-methyl)-3-cyclohexyl-isochroman-5,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.73E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007141![]() (1-Aminomethyl-3-benzhydryl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50453080![]() (CHEMBL2114209) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007146![]() (1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007137![]() (1-Aminomethyl-3-(3-hydroxy-phenyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007141![]() (1-Aminomethyl-3-benzhydryl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007131![]() (3-Cyclohexyl-1-[(3-hydroxy-propylamino)-methyl]-is...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.74E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007133![]() (1-Aminomethyl-3-butyl-isochroman-5,6-diol | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007135![]() (1-Aminomethyl-isochroman-5,6-diol | CHEMBL87958) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007144![]() (3-Cyclohexyl-1-prop-2-ynylaminomethyl-isochroman-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007136![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007138![]() (3-Cyclohexyl-1-cyclopropylaminomethyl-isochroman-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 52 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007149![]() (1-Aminomethyl-3-cyclopentylmethyl-isochroman-5,6-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 427 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007152![]() (1-Aminomethyl-3-(4-iodo-phenyl)-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2 | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50004822![]() ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50004822![]() ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 386 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007125![]() (3-Cyclohexyl-1-methylaminomethyl-isochroman-5,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007132![]() (1-(Benzylamino-methyl)-3-cyclohexyl-isochroman-5,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007140![]() (1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-dio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 47 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007131![]() (3-Cyclohexyl-1-[(3-hydroxy-propylamino)-methyl]-is...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007126![]() (1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007146![]() (1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 782 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50453079![]() (CHEMBL2115213) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007128![]() (1-Aminomethyl-3-phenethyl-isochroman-5,6-diol | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007145![]() (1-Aminomethyl-isochroman-5,6-diol spirocyclohexane...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 69 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007133![]() (1-Aminomethyl-3-butyl-isochroman-5,6-diol | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 359 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatum | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007134![]() (1-Aminomethyl-3-phenyl-isochroman-5,6-diol | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007123![]() (1-Aminomethyl-3-(4-bromo-phenyl)-isochroman-5,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007143![]() (1-Aminomethyl-3-(4-methoxy-benzyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007151![]() (1-Aminomethyl-3-prop-2-ynyl-isochroman-5,6-diol | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 67 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007138![]() (3-Cyclohexyl-1-cyclopropylaminomethyl-isochroman-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 124 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007139![]() (1-Aminomethyl-3-(3-methoxy-phenyl)-isochroman-5,6-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007125![]() (3-Cyclohexyl-1-methylaminomethyl-isochroman-5,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary gland | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50007148![]() (1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retina | J Med Chem 34: 2561-9 (1991) Article DOI: 10.1021/jm00112a034 BindingDB Entry DOI: 10.7270/Q2HM57DN | |||||||||||
More data for this Ligand-Target Pair |