BindingDB logo
myBDB logout

PubMed code 1656043

Compile data set for download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphodiesterase 4


(Homo sapiens-Homo sapiens (Human)-Homo sapiens (hu...)
BDBM50228874
PNG
(CHEMBL102012)
Show SMILES CNNc1[nH]nc(-n2nc(C)cc2C)c2nc3ccccc3c12
Show InChI InChI=1S/C16H17N7/c1-9-8-10(2)23(22-9)16-14-13(15(19-17-3)20-21-16)11-6-4-5-7-12(11)18-14/h4-8,17,19-20H,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.18E+5n/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Inhibition of canine heart phosphodiesterase 4


J Med Chem 34: 3023-9 (1991)


Article DOI: 10.1021/jm00114a010
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(Homo sapiens-Homo sapiens (Human)-Homo sapiens (hu...)
BDBM50228875
PNG
(CHEMBL101117)
Show SMILES NNC(=O)c1n[nH]c2c3nc4ccccc4c3c(NN)nn12
Show InChI InChI=1S/C12H11N9O/c13-16-9-7-5-3-1-2-4-6(5)15-8(7)10-18-19-11(12(22)17-14)21(10)20-9/h1-4,18H,13-14H2,(H,16,20)(H,17,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.21E+5n/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Inhibition of canine heart phosphodiesterase 4


J Med Chem 34: 3023-9 (1991)


Article DOI: 10.1021/jm00114a010
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(Homo sapiens-Homo sapiens (Human)-Homo sapiens (hu...)
BDBM34651
PNG
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)
Show SMILES Nc1cc(c[nH]c1=O)-c1ccncc1
Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.26E+5n/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Inhibition of canine heart phosphodiesterase 4


J Med Chem 34: 3023-9 (1991)


Article DOI: 10.1021/jm00114a010
More data for this
Ligand-Target Pair
Phosphodiesterase 4


(Homo sapiens-Homo sapiens (Human)-Homo sapiens (hu...)
BDBM50228876
PNG
(CHEMBL555954)
Show SMILES Cl.Cc1cc(C)n(n1)-c1[nH]nc(NN)c2c1nc1ccccc21
Show InChI InChI=1S/C15H15N7.ClH/c1-8-7-9(2)22(21-8)15-13-12(14(18-16)19-20-15)10-5-3-4-6-11(10)17-13;/h3-7,20H,16H2,1-2H3,(H,18,19);1H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.48E+5n/an/an/an/an/an/a



Universidad de Navarra

Curated by ChEMBL


Assay Description
Inhibition of canine heart phosphodiesterase 4


J Med Chem 34: 3023-9 (1991)


Article DOI: 10.1021/jm00114a010
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%