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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007314 (CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007316 ((3,4-Dichloro-benzyl)-methyl-(2-pyrrolidin-1-yl-cy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was tested for the inhibitory activity against Sigma opioid receptor by using [3H]-(+)-3-PPP as radioligand in guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50003743 ((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50003743 ((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007312 (CHEMBL320828 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007315 (CHEMBL103065 | [2-(3,4-Dichloro-phenyl)-ethyl]-eth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007313 (CHEMBL102695 | [2-(3,4-Dichloro-phenyl)-ethyl]-eth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was tested for the inhibitory activity against Sigma opioid receptor by using [3H]-(+)-3-PPP as radioligand in guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50003747 ((+)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007322 (2-(3,4-Dichloro-phenyl)-N-(2-pyrrolidin-1-yl-cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was tested for the inhibitory activity against Sigma opioid receptor by using [3H]-(+)-3-PPP as radioligand in guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007319 (CHEMBL103849 | Cyclopropylmethyl-[2-(3,4-dichloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007321 (CHEMBL316797 | [2-(3,4-Dichloro-phenyl)-ethyl]-pro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50003749 ((2S)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007317 (CHEMBL104992 | [2-(3,4-Dichloro-phenyl)-ethyl]-pro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007318 (2-(3,4-Dichloro-phenyl)-N-(2-pyrrolidin-1-yl-cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 146 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50007320 (CHEMBL103519 | Cyclopropylmethyl-[2-(3,4-dichloro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 412 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sigma non-opioid intracellular receptor 1 (HUMAN) | BDBM50003755 ((2R)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 538 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibiton of [3H]-(+)-3-PPP binding to sigma of guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat)) | BDBM50007314 (CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was tested for the inhibitory concentration against phencyclidine by using [3H]-TCP as radioligand at PCP receptor in guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)) | BDBM50007314 (CHEMBL104834 | [2-(3,4-Dichloro-phenyl)-ethyl]-(2-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 8.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Compound was tested for the inhibitory concentration against dopamine receptor D2 by using [3H]-()-sulpiride) as radioligand in guinea pig brain | J Med Chem 34: 3058-65 (1991) Article DOI: 10.1021/jm00114a015 BindingDB Entry DOI: 10.7270/Q2VX0FGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
