Affinity Data by PubMed id=1671414

PubMed code 1671414

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Opioid receptor activity in terms of inhibition of [3H]-dihydromorphine binding in rat brain membrane				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membraneto Dopamine receptor D2				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50007421 (CHEMBL59245 \| Propionic acid 1-[4-(4-fluoro-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to opioid receptor mu in rat brain membrane.				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50007421 (CHEMBL59245 \| Propionic acid 1-[4-(4-fluoro-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to Opioid receptor mu 1 in rat brain membrane.				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007421 (CHEMBL59245 \| Propionic acid 1-[4-(4-fluoro-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Neuroleptic activity in terms of [3H]-spiroperidol binding to dopamine receptor D2 in rat striatal membrane.				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007421 (CHEMBL59245 \| Propionic acid 1-[4-(4-fluoro-phenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Neuroleptic activity in terms of [3H]-spiroperidol binding to Dopamine receptor D2 in rat striatal membrane.				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007420 (CHEMBL418289 \| Propionic acid 1-[4-(4-fluoro-pheny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Neuroleptic activity in terms of [3H]-spiroperidol binding to Dopamine receptor D2 in rat striatal membrane.				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membrane to Dopamine receptor D2				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50007420 (CHEMBL418289 \| Propionic acid 1-[4-(4-fluoro-pheny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to Opioid receptor mu 1 in rat brain membrane.				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanità Curated by ChEMBL					Assay Description Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membrane to Dopamine receptor D2				J Med Chem 34: 194-7 (1991) Article DOI: 10.1021/jm00105a029 BindingDB Entry DOI: 10.7270/Q2GM867T
Istituto Superiore di Sanità Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%