BindingDB logo
myBDB logout

PubMed code 1671420

Compile data set for download or QSAR
Found 49 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(RAT)
BDBM22868
PNG
(11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-b...)
Show SMILES CN1CCC(CC1)=C1c2ccccc2CCc2cccnc12
Show InChI InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
3.90n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM35938
PNG
(1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...)
Show SMILES CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1
Show InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
5.5n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007464
PNG
(4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b...)
Show SMILES Clc1ccc2c(CCc3cccnc3C2=C2CCN(CC2)C=O)c1
Show InChI InChI=1S/C20H19ClN2O/c21-17-5-6-18-16(12-17)4-3-15-2-1-9-22-20(15)19(18)14-7-10-23(13-24)11-8-14/h1-2,5-6,9,12-13H,3-4,7-8,10-11H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
21n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007461
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CCC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C22H23ClN2O/c1-2-20(26)25-12-9-15(10-13-25)21-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-22(16)21/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
48n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007465
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CCCC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C23H25ClN2O/c1-2-4-21(27)26-13-10-16(11-14-26)22-20-9-8-19(24)15-18(20)7-6-17-5-3-12-25-23(17)22/h3,5,8-9,12,15H,2,4,6-7,10-11,13-14H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
51n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007454
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(C)(C)C(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C24H27ClN2O/c1-24(2,3)23(28)27-13-10-16(11-14-27)21-20-9-8-19(25)15-18(20)7-6-17-5-4-12-26-22(17)21/h4-5,8-9,12,15H,6-7,10-11,13-14H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
81n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007466
PNG
(CHEMBL140924 | [4-(8-Chloro-5,6-dihydro-benzo[5,6]...)
Show SMILES Clc1ccc2c(CCc3cccnc3C2=C2CCN(CC2)C(=O)c2ccccc2)c1
Show InChI InChI=1S/C26H23ClN2O/c27-22-10-11-23-21(17-22)9-8-19-7-4-14-28-25(19)24(23)18-12-15-29(16-13-18)26(30)20-5-2-1-3-6-20/h1-7,10-11,14,17H,8-9,12-13,15-16H2
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
190n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007470
PNG
(1-[4-(8-Methyl-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(C)cc2CCc2cccnc12
Show InChI InChI=1S/C22H24N2O/c1-15-5-8-20-19(14-15)7-6-18-4-3-11-23-22(18)21(20)17-9-12-24(13-10-17)16(2)25/h3-5,8,11,14H,6-7,9-10,12-13H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
190n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007463
PNG
(CHEMBL124466 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...)
Show SMILES CN(CC\C=C1/c2ccc(Cl)cc2CCc2cccnc12)C(C)=O
Show InChI InChI=1S/C20H21ClN2O/c1-14(24)23(2)12-4-6-19-18-10-9-17(21)13-16(18)8-7-15-5-3-11-22-20(15)19/h3,5-6,9-11,13H,4,7-8,12H2,1-2H3/b19-6+
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
290n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007473
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
320n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM22876
PNG
(CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...)
Show SMILES CCOC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

PubMed
350n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007462
PNG
(1-[4-(8-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(F)cc2CCc2cccnc12
Show InChI InChI=1S/C21H21FN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
720n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007474
PNG
(CHEMBL141432 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...)
Show SMILES CN(CC\C=C1\c2ccc(Cl)cc2CCc2cccnc12)C(C)=O
Show InChI InChI=1S/C20H21ClN2O/c1-14(24)23(2)12-4-6-19-18-10-9-17(21)13-16(18)8-7-15-5-3-11-22-20(15)19/h3,5-6,9-11,13H,4,7-8,12H2,1-2H3/b19-6-
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
850n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007472
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)C1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C22H22ClNO/c1-14(25)15-4-6-16(7-5-15)21-20-11-10-19(23)13-18(20)9-8-17-3-2-12-24-22(17)21/h2-3,10-13,15H,4-9H2,1H3/b21-16-
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
1.20E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007460
PNG
(1-[4-(9-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(Cl)ccc2CCc2cccnc12
Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
1.50E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007456
PNG
(1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1...)
Show SMILES COc1ccc2c(CCc3cccnc3C2=C2CCN(CC2)C(C)=O)c1
Show InChI InChI=1S/C22H24N2O2/c1-15(25)24-12-9-16(10-13-24)21-20-8-7-19(26-2)14-18(20)6-5-17-4-3-11-23-22(17)21/h3-4,7-8,11,14H,5-6,9-10,12-13H2,1-2H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
1.60E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007467
PNG
(1-[4-(5,6-Dihydro-benzo[5,6]cyclohepta[1,2-b]pyrid...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccccc2CCc2cccnc12
Show InChI InChI=1S/C21H22N2O/c1-15(24)23-13-10-17(11-14-23)20-19-7-3-2-5-16(19)8-9-18-6-4-12-22-21(18)20/h2-7,12H,8-11,13-14H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
2.00E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007458
PNG
(1-[4-(9-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(F)ccc2CCc2cccnc12
Show InChI InChI=1S/C21H21FN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
2.90E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007459
PNG
(1-[4-(8,9-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(Cl)c(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C21H20Cl2N2O/c1-13(26)25-9-6-14(7-10-25)20-17-12-19(23)18(22)11-16(17)5-4-15-3-2-8-24-21(15)20/h2-3,8,11-12H,4-7,9-10H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
3.10E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50406423
PNG
(CHEMBL334318)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C22H23NO/c1-16(24)23-14-12-19(13-15-23)22-20-8-4-2-6-17(20)10-11-18-7-3-5-9-21(18)22/h2-9H,10-15H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
5.00E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007469
PNG
(1-{4-[(4-Chloro-phenyl)-pyridin-2-yl-methylene]-pi...)
Show SMILES CC(=O)N1CCC(CC1)=C(c1ccc(Cl)cc1)c1ccccn1
Show InChI InChI=1S/C19H19ClN2O/c1-14(23)22-12-9-16(10-13-22)19(18-4-2-3-11-21-18)15-5-7-17(20)8-6-15/h2-8,11H,9-10,12-13H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
>6.30E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007475
PNG
(1-[4-(8-Hydroxy-5,6-dihydro-benzo[5,6]cyclohepta[1...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(O)cc2CCc2cccnc12
Show InChI InChI=1S/C21H22N2O2/c1-14(24)23-11-8-15(9-12-23)20-19-7-6-18(25)13-17(19)5-4-16-3-2-10-22-21(16)20/h2-3,6-7,10,13,25H,4-5,8-9,11-12H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
>6.30E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Histamine H1 receptor


(RAT)
BDBM50007457
PNG
(1-[4-(8,9-Difluoro-5,6-dihydro-benzo[5,6]cyclohept...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(F)c(F)cc2CCc2cccnc12
Show InChI InChI=1S/C21H20F2N2O/c1-13(26)25-9-6-14(7-10-25)20-17-12-19(23)18(22)11-16(17)5-4-15-3-2-8-24-21(15)20/h2-3,8,11-12H,4-7,9-10H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
1.00E+4n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50000714
PNG
(3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...)
Show SMILES Cc1nnc2CN=C(c3cc(CCC(=O)N4CCOCC4)sc3-n12)c1ccccc1Cl
Show InChI InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 40n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007473
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 610n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007462
PNG
(1-[4-(8-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(F)cc2CCc2cccnc12
Show InChI InChI=1S/C21H21FN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 670n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007455
PNG
(1-[4-(8-Bromo-5,6-dihydro-benzo[5,6]cyclohepta[1,2...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(Br)cc2CCc2cccnc12
Show InChI InChI=1S/C21H21BrN2O/c1-14(25)24-11-8-15(9-12-24)20-19-7-6-18(22)13-17(19)5-4-16-3-2-10-23-21(16)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 810n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007458
PNG
(1-[4-(9-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(F)ccc2CCc2cccnc12
Show InChI InChI=1S/C21H21FN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 820n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007457
PNG
(1-[4-(8,9-Difluoro-5,6-dihydro-benzo[5,6]cyclohept...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(F)c(F)cc2CCc2cccnc12
Show InChI InChI=1S/C21H20F2N2O/c1-13(26)25-9-6-14(7-10-25)20-17-12-19(23)18(22)11-16(17)5-4-15-3-2-8-24-21(15)20/h2-3,8,11-12H,4-7,9-10H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007470
PNG
(1-[4-(8-Methyl-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(C)cc2CCc2cccnc12
Show InChI InChI=1S/C22H24N2O/c1-15-5-8-20-19(14-15)7-6-18-4-3-11-23-22(18)21(20)17-9-12-24(13-10-17)16(2)25/h3-5,8,11,14H,6-7,9-10,12-13H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007467
PNG
(1-[4-(5,6-Dihydro-benzo[5,6]cyclohepta[1,2-b]pyrid...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccccc2CCc2cccnc12
Show InChI InChI=1S/C21H22N2O/c1-15(24)23-13-10-17(11-14-23)20-19-7-3-2-5-16(19)8-9-18-6-4-12-22-21(18)20/h2-7,12H,8-11,13-14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50002831
PNG
((2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahyd...)
Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007459
PNG
(1-[4-(8,9-Dichloro-5,6-dihydro-benzo[5,6]cyclohept...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(Cl)c(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C21H20Cl2N2O/c1-13(26)25-9-6-14(7-10-25)20-17-12-19(23)18(22)11-16(17)5-4-15-3-2-8-24-21(15)20/h2-3,8,11-12H,4-7,9-10H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007461
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CCC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C22H23ClN2O/c1-2-20(26)25-12-9-15(10-13-25)21-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-22(16)21/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007456
PNG
(1-[4-(8-Methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1...)
Show SMILES COc1ccc2c(CCc3cccnc3C2=C2CCN(CC2)C(C)=O)c1
Show InChI InChI=1S/C22H24N2O2/c1-15(25)24-12-9-16(10-13-24)21-20-8-7-19(26-2)14-18(20)6-5-17-4-3-11-23-22(17)21/h3-4,7-8,11,14H,5-6,9-10,12-13H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007460
PNG
(1-[4-(9-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(Cl)ccc2CCc2cccnc12
Show InChI InChI=1S/C21H21ClN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007475
PNG
(1-[4-(8-Hydroxy-5,6-dihydro-benzo[5,6]cyclohepta[1...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccc(O)cc2CCc2cccnc12
Show InChI InChI=1S/C21H22N2O2/c1-14(24)23-11-8-15(9-12-23)20-19-7-6-18(25)13-17(19)5-4-16-3-2-10-22-21(16)20/h2-3,6-7,10,13,25H,4-5,8-9,11-12H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 8.70E+3n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007464
PNG
(4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b...)
Show SMILES Clc1ccc2c(CCc3cccnc3C2=C2CCN(CC2)C=O)c1
Show InChI InChI=1S/C20H19ClN2O/c21-17-5-6-18-16(12-17)4-3-15-2-1-9-22-20(15)19(18)14-7-10-23(13-24)11-8-14/h1-2,5-6,9,12-13H,3-4,7-8,10-11H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007469
PNG
(1-{4-[(4-Chloro-phenyl)-pyridin-2-yl-methylene]-pi...)
Show SMILES CC(=O)N1CCC(CC1)=C(c1ccc(Cl)cc1)c1ccccn1
Show InChI InChI=1S/C19H19ClN2O/c1-14(23)22-12-9-16(10-13-22)19(18-4-2-3-11-21-18)15-5-7-17(20)8-6-15/h2-8,11H,9-10,12-13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007465
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CCCC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C23H25ClN2O/c1-2-4-21(27)26-13-10-16(11-14-26)22-20-9-8-19(24)15-18(20)7-6-17-5-3-12-25-23(17)22/h3,5,8-9,12,15H,2,4,6-7,10-11,13-14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50406423
PNG
(CHEMBL334318)
Show SMILES CC(=O)N1CCC(CC1)=C1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C22H23NO/c1-16(24)23-14-12-19(13-15-23)22-20-8-4-2-6-17(20)10-11-18-7-3-5-9-21(18)22/h2-9H,10-15H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a 4.10E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM35938
PNG
(1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...)
Show SMILES CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1
Show InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007466
PNG
(CHEMBL140924 | [4-(8-Chloro-5,6-dihydro-benzo[5,6]...)
Show SMILES Clc1ccc2c(CCc3cccnc3C2=C2CCN(CC2)C(=O)c2ccccc2)c1
Show InChI InChI=1S/C26H23ClN2O/c27-22-10-11-23-21(17-22)9-8-19-7-4-14-28-25(19)24(23)18-12-15-29(16-13-18)26(30)20-5-2-1-3-6-20/h1-7,10-11,14,17H,8-9,12-13,15-16H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007474
PNG
(CHEMBL141432 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...)
Show SMILES CN(CC\C=C1\c2ccc(Cl)cc2CCc2cccnc12)C(C)=O
Show InChI InChI=1S/C20H21ClN2O/c1-14(24)23(2)12-4-6-19-18-10-9-17(21)13-16(18)8-7-15-5-3-11-22-20(15)19/h3,5-6,9-11,13H,4,7-8,12H2,1-2H3/b19-6-
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM22876
PNG
(CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...)
Show SMILES CCOC(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007463
PNG
(CHEMBL124466 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...)
Show SMILES CN(CC\C=C1/c2ccc(Cl)cc2CCc2cccnc12)C(C)=O
Show InChI InChI=1S/C20H21ClN2O/c1-14(24)23(2)12-4-6-19-18-10-9-17(21)13-16(18)8-7-15-5-3-11-22-20(15)19/h3,5-6,9-11,13H,4,7-8,12H2,1-2H3/b19-6+
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007472
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)C1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C22H22ClNO/c1-14(25)15-4-6-16(7-5-15)21-20-11-10-19(23)13-18(20)9-8-17-3-2-12-24-22(17)21/h2-3,10-13,15H,4-9H2,1H3/b21-16-
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM22868
PNG
(11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-b...)
Show SMILES CN1CCC(CC1)=C1c2ccccc2CCc2cccnc12
Show InChI InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
Platelet activating factor receptor


(HUMAN)
BDBM50007454
PNG
(1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(C)(C)C(=O)N1CCC(CC1)=C1c2ccc(Cl)cc2CCc2cccnc12
Show InChI InChI=1S/C24H27ClN2O/c1-24(2,3)23(28)27-13-10-16(11-14-27)21-20-9-8-19(25)15-18(20)7-6-17-5-4-12-26-22(17)21/h4-5,8-9,12,15H,6-7,10-11,13-14H2,1-3H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...


Citation and Details
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%